Results 81 to 90 of about 106,174 (376)

Myocardial ischemic effects on cardiac electro-mechanical activity [PDF]

open access: yesarXiv, 2021
In this work, we investigated the effect of varying strength of Hyperkalemia and Hypoxia, in human cardiac tissue with a local ischemic subregion, on the electrical and mechanical activity of healthy and ischemic zones of the cardiac muscle. The Monodomain model in a deforming domain is taken with the addition of mechanical feedback and stretch ...
arxiv  

Role of Implantable Cardioverter Defibrillators in the Treatment of Hypertrophic Cardiomyopathy [PDF]

open access: yes, 2005
Hypertrophic cardiomyopathy (HCM) is an important cardiovascular disease with sudden cardiac death as the most devastating presentation. Implantable cardioverter defibrillators (ICD) are the optimal therapy for prevention of sudden death from ventricular
Francis, Johnson   +2 more
core   +1 more source

Comprehensive multi-factor analysis and exploration for the pathogenesis of non-ischemic cardiomyopathy and ischemic cardiomyopathy

open access: yesCellular and Molecular Biology, 2020
Cardiomyopathy is a group of heterogeneous diseases that negatively affect cardiac function. Twenty-five years ago, clinical researchers began to realize that cardiomyopathy is an important and fairly common heart disease. Although many aspects of the pathogenesis of cardiomyopathy have been explored by biologists, the molecular mechanisms remain ...
Lin Ma, Fengling Li, Lin Cheng
openaire   +4 more sources

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

open access: yesAdvanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin   +15 more
wiley   +1 more source

Physician preferences for revascularization in patients with ischemic cardiomyopathy: Defining equipoise from web-based surveys

open access: yesAmerican Heart Journal Plus, 2023
Background: The optimal revascularization approach in patients with heart failure with reduced ejection fraction (HFrEF) and ischemic heart disease (“ischemic cardiomyopathy”) is unknown.
Amrita Mukhopadhyay   +6 more
doaj  

Evidence regarding clinical use of microvolt T-wave alternans [Accuracy of microvolt T-wave alternans testing] [PDF]

open access: yes, 2011
Background: Microvolt T-wave alternans (MTWA) testing in many studies has proven to be a highly accurate predictor of ventricular tachyarrhythmic events (VTEs) in patients with risk factors for sudden cardiac death (SCD) but without a prior history of ...
Cohen, Richard J.   +2 more
core  

Translational aspects of cardiac cell therapy. [PDF]

open access: yes, 2015
Cell therapy has been intensely studied for over a decade as a potential treatment for ischaemic heart disease. While initial trials using skeletal myoblasts, bone marrow cells and peripheral blood stem cells showed promise in improving cardiac function,
Ardehali, Reza   +3 more
core   +1 more source

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

open access: yesAdvanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Myocardial fibrosis in desmin-related hypertrophic cardiomyopathy

open access: yesJournal of Cardiovascular Magnetic Resonance, 2010
Desmin-related myopathy (DRM) is known to cause different types of cardiomyopathy. Late gadolinium enhancement cardiovascular magnetic resonance (CMR) has been shown to identify fibrosis in ischemic and non-ischemic cardiomyopathies.
Dai Qinyi   +4 more
doaj   +1 more source

Cardiotoxicity with vascular endothelial growth factor inhibitor therapy [PDF]

open access: yes, 2018
Angiogenesis inhibitors targeting the vascular endothelial growth factor (VEGF) signaling pathway (VSP) have been important additions in the therapy of various cancers, especially renal cell carcinoma and colorectal cancer.
Herrmann, Joerg, Touyz, Rhian M.
core   +2 more sources

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