Results 141 to 150 of about 600,406 (349)
Advanced Science, EarlyView.MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang +12 more
wiley +1 more source
Differential Features of Culprit Intracranial Atherosclerotic Lesions: A Whole-Brain Vessel Wall Imaging Study in Patients With Acute Ischemic Stroke. [PDF]
, 2018 BackgroundIntracranial atherosclerotic disease tends to affect multiple arterial segments. Using whole-brain vessel wall imaging, we sought to study the differences in plaque features among various types of plaques in patients with a recent unilateral ...
Bi, Xiaoming +12 more
core
Advanced Science, EarlyView.Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl +12 more
wiley +1 more source
Improving the quality of life an empowerment of our patients with ischemic heart disease [PDF]
, 2022 Bárbara González Batista +7 more
openalex +1 more source
Statistical methods of SNP data analysis with applications [PDF]
, 2011 Various statistical methods important for genetic analysis are considered and developed. Namely, we concentrate on the multifactor dimensionality reduction, logic regression, random forests and stochastic gradient boosting.
Bulinski, Alexander +3 more
core +2 more sources
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Advanced Science, EarlyView.Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source
Scientific ReportsRecent studies reported the long-term cardiovascular risk of preeclampsia. However, only a few studies have investigated the association between preeclampsia and long-term cardiovascular disease in Asian populations, although there could be racial/ethnic
Eun-Saem Choi +8 more
doaj +1 more source
Association between types of physical activity and risk of ischemic heart disease based on US Guidelines: A systematic review and meta-analysis [PDF]
, 2023 Jaewoo Cha, Jeehyun Kim, Kwan Hong
openalex +1 more source
MRI and MSCT for the Assessment of Myocardial Function and Viability [PDF]
, 2006 MRI is a versatile non-invasive imaging modality that can be applied in patients and in experimental models of ischemic heart disease ...
Baks, T. (Timo)
core +2 more sources
Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes
Advanced Science, EarlyView.Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis +9 more
wiley +1 more source