Results 11 to 20 of about 11,505 (132)

A novel selective stabilizer of the ryanodine receptor 2 prevents stress‐induced ventricular arrhythmias without impairing cardiac function

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Aberrant activation of type 2 ryanodine receptors (RyR2) causes lethal arrhythmias, such as catecholaminergic polymorphic ventricular tachycardia (CPVT). Developing drugs that suppress RyR2 hyperactivation may be key to novel arrhythmia treatments.
Nagomi Kurebayashi, Masami Kodama, Hana Inoue, Masato Konishi, Masami Sugihara, Takashi Murayama, Ryosuke Ishida, Koichiro Ishii, Shuichi Mori, Yukari Endo, Xi Zeng, Yukiko U. Inoue, Takayoshi Inoue, Satoru Noguchi, Hajime Nishio, Eri Nakashima, Norio Suzuki, Noriko Nakaya, Ryushi Sato, Yuya Otori, Ayuna Tsutsumi, Mirei Takahashi, Takayuki Oka, Haruo Ogawa, Kayoko Kanamitsu, Hiroyuki Kusuhara, Utako Yokoyama, Junko Kurokawa, Hiroyuki Kagechika, Takashi Sakurai   +29 more
wiley   +1 more source

Mitral regurgitation and decompensated heart failure in a young pregnant pony mare: An aetiological challenge

Equine Veterinary Education, EarlyView.
Summary A 4‐year‐old, 6‐month pregnant, Welsh pony mare presented with severe acute clinical signs including depression, anorexia, pale mucous membranes, tachycardia with a grade 4/6 holosystolic murmur and moderate expiratory dyspnoea with diffuse wheezes. There was no evidence of placentitis or fetal distress.
M. F. David, L. Cannon, A. Tortereau, A. Thomas‐Cancian, I. Desjardins   +4 more
wiley   +1 more source

Demographic and Clinical Features in Patients with Mitral Insufficiency of Ischemic Genesis

Ukrainian journal of cardiovascular surgery, 2020
Myocardial infarction is often associated with ischemic mitral regurgitation. In most patients, ischemic mitral regurgitation develops gradually due to remodeling of the ischemic myocardium and changes in hemodynamics in the left ventricle. Ischemic mitral regurgitation is associated with heart diseases and mortality and is therefore considered an ...
S. A. Rudenko, S. V. Potashev, A. V. Rudenko   +2 more
openaire   +3 more sources

Identification of the individual cardiac contraction threshold during high‐frame‐rate stress echocardiography

Experimental Physiology, EarlyView.
Abstract The clinical assessment of cardiovascular function during exercise using stress echocardiography is essential for accurate cardiac diagnosis. However, normal limitations of cardiac deformation responses to increasing physical exertion remain poorly understood.
Fabian Spahiu, Max Hagemann, Michelle Ottlik, Moritz Lampkemeyer, Eric J. Stöhr   +4 more
wiley   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson, Maria Teresa Fiorenza   +1 more
wiley   +1 more source

Two Cases of Post‐Operative Coronary–Cameral Fistulas After Unusual Myectomy Procedures

Clinical Case Reports, Volume 14, Issue 6, June 2026.
Post‐surgical coronary–cameral fistulas (CCF) can occur after various myectomy procedures. Here we present one case of CCF after resection of the hypertrophied RV muscle bundle in double‐chambered RV (DCRV) and one case of CCF after subaortic web resection.
Neda Toofaninejad, Arezoo Hajiali, Mahtab Hatami, Saba Mohammadzadeh   +3 more
wiley   +1 more source

Impact of mitral insufficiency on reoperative coronary artery surgery in ischemic cardiomyopathy patients? [PDF]

European Journal of Cardio-Thoracic Surgery, 2004
To determine the impact of mitral insufficiency on survival after reoperative coronary artery bypass grafting (CABG) in ischemic cardiomyopathy patients.We retrospectively studied 891 (Initial 708, Redo 183) consecutive CABG patients (1993-2002) with ejection fraction (EF) 35% or less.mean age=67.0+/-10.5 yrs, men=77.1%, EF=26.4+/-7.4%, mean CCS=3.47+/-
Nan, Wang, Saida, Campwala, Saied, Habibipour, Darren, Hodgins, Ramdas, Pai, Anees, Razzouk   +5 more
openaire   +2 more sources

Efficacy and Safety of Catheter Ablation in Very Elderly Patients With Atrial Fibrillation: Short‐ To Mid‐Term Outcomes From a Multicenter Study

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
Patients aged ≥ 80 years with atrial fibrillation underwent catheter ablation. At 2 years, the recurrence‐free survival rate was 85.8% in paroxysmal AF and 63.6% in persistent AF (p = 0.024), and periprocedural complications occurred in 12.0%, including severe complications in 3.3%.
Takumi Tamura, Yoshihisa Naruse, Taro Narumi, Yuki Tokonami, Yasukazu Takazawa, Kazuki Ito, Yutaro Kaneko, Makoto Sano, Ryosuke Takeuchi, Natsuko Hosoya, Masahiro Muto, Ryuta Henmi, Ryo Sugiura, Keisuke Miyajima, Yuichiro Maekawa   +14 more
wiley   +1 more source

Electrophysiological Substrate and Ablation Outcomes in Atrial Fibrillation With Hypertrophic Cardiomyopathy: A Propensity‐Matched Multicenter Study

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
Multicentre retrospective propensity‐score‐matched cohort study (n = 286; 3 centres, Pakistan; 2015‐2023) comparing electrophysiological substrate and 12‐month ablation outcomes in patients with atrial fibrillation and hypertrophic cardiomyopathy (HCM‐AF, red) versus lone atrial fibrillation (Lone AF, green; 1:1 PSM on 14 covariates).
Umair Abrar, Fazal Ghaffar, Muhammad Zuhaid, Huzaifa Bin Afzaal, Palwasha Abbasi, Muhammad Hasnain Iqbal, Moʻminov Jahongir Zokirjon oʻgʻli, Sifat Ullah Safi   +7 more
wiley   +1 more source

Efficacy of a Novel Ablation Index Algorithm for Cavotricuspid Isthmus Ablation Using a Flexible‐Tip Ablation Catheter

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
AutoMark Index (AI) is a novel ablation algorithm that combines contact force, radiofrequency current, and application to provide real‐time lesion formation. AI‐guided CTI ablation protocol is efficient in shortening RF duration for acute bidirectional CTI block and CTI procedure time compared to the conventional 40 W ablation protocol.
Koji Sudo, Kenji Kuroki, Tetsuya Asakawa, Kazuya Nakagawa, Jumpei Saito, Chisa Asahina, Takeaki Goto, Maoko Atsumi, Tomoaki Hasegawa, Yasuteru Yamauchi, Kazutaka Aonuma, Akira Sato   +11 more
wiley   +1 more source