Results 171 to 180 of about 924,610 (305)

Predictors of Mortality in Posterior Circulation Ischemic Stroke. [PDF]

Medicina (Kaunas)
Rsovac Ivanović S, Vitošević F, Bogićević D, Senji D, Nikčević Krivokapić L, Vukićević M, Rančić N, Mašulović D, Georgievski-Brkić B.   +8 more
europepmc   +1 more source

Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

Advanced Science, EarlyView.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin, Dilara Aylar, Archna Sharma, Ping Wang   +3 more
wiley   +1 more source

No-reflow in acute ischemic stroke: mechanisms, measurements, and molecular markers. [PDF]

Front Neurol
Bayona H, Granja MF, Useche JN.
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

The morphometric features derived as the predictors of acute ischemic stroke recurrence. [PDF]

Front Neurosci
Sun J, Dong P, Wang L, Long J, Qi Y, Song L.   +5 more
europepmc   +1 more source

Transient ischemic attacks: predictability of future ischemic stroke or transient ischemic attack events

, 2014
Harsh V Gupta,1 Ann M Farrell,2 Manoj K Mittal31Department of Neurology, The University of Arkansas Medical Sciences, Little Rock, AR, 2Department of Knowledge and Evaluation Research, Mayo Clinic, Rochester, MN, 3Department of Neurology, The University ...
Gupta HV, Mittal MK, Farrell AM
core  

Endothelial miR‐15a/16‐1 Regulation of SYNE1 Mediates Structural and Functional Recovery after Traumatic Brain Injury

Advanced Science, EarlyView.
Endothelial miR‐15a/16‐1 deletion promotes long‐term recovery after traumatic brain injury by restoring SYNE1 expression. Enhanced endothelial SYNE1 preserves vascular integrity, protects white and gray matter, and improves neurological function. The endothelial miR‐15a/16‐1–SYNE1 axis emerges as a key regulator of neurovascular repair and a potential ...
Shun Li, Na Qiu, Chao Zhou, Andrew Ni, Ping Sun, Jia‐Jun Liu, Xin‐Lei Huang, Tian‐Qing Xiong, Yu‐Chi Zhang, Hai‐Zhou Liu, Xiao‐Tao Xu, Rui Wang, Shi‐Qing Zhang, Yu‐Xin Zhang, Silvia Liu, C. Edward Dixon, Jun Chen, Ke‐Jie Yin   +17 more
wiley   +1 more source

Progress in Intra-Arterial Stem Cell Therapy for Ischemic Stroke: A Review. [PDF]

Stroke Vasc Interv Neurol
McMillan N, Thakkar R, Kuddannaya S, Chavda V, Desai S, Yavagal DR.   +5 more
europepmc   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Leptomeningeal Collaterals Constitute an Immune-Responsive Vascular Niche in Ischemic Stroke. [PDF]

Stroke
Ju J, Smith K, Tanchanco C, de Jager C, Svetanant T, Patel BM, Theus MH.   +6 more
europepmc   +1 more source