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Pediatric Ischemic Stroke

Continuum, 2023
Pediatric cerebrovascular disease is one of the leading causes of death and disability in children. Survivors of childhood stroke and their families are often left to cope with long-lasting sequelae, such as barriers to school reentry and long-term challenges in attaining independence as adults. Because childhood stroke is rare and providers may not be
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Acute Ischemic Stroke

AACN Advanced Critical Care, 2018
Acute ischemic stroke is a major cause of mortality and morbidity in the United States and worldwide. Despite the development of specialized stroke centers, mortality and morbidity as a result of acute ischemic strokes can and do happen anywhere. These strokes are emergency situations requiring immediate intervention.
Bryan, Boling, Katie, Keinath
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Sonothrombolysis in Ischemic Stroke

Current Treatment Options in Neurology, 2013
Acute ischemic stroke remains one of the most devastating diseases when it comes to morbidity and mortality, not to mention the personal and economic burden that occurs in long-term. Intravenous thrombolysis with tissue plasminogen activator (tPA) is the only effective acute stroke therapy that improves outcome if given up to 4.5 hours from symptom ...
Kristian, Barlinn, Andrei V, Alexandrov
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Alcohol and Ischemic Stroke

Nutrition Reviews, 2009
Stroke mortality represents the third leading cause of death after coronary artery disease and all cancers. Various studies have reported a protective effect of light to moderate alcohol consumption on ischemic stroke risk. The relationship between alcohol and ischemic stroke risk appears to be causal. Potential mechanisms and recommendations for daily
P M, Suter, W, Vetter
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Autophagy in ischemic stroke

Progress in Neurobiology, 2018
Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins, damaged organelles and misfolded proteins are degraded and recycled for the maintenance of cellular homeostasis and normal cellular functions. Autophagy plays an important homeostatic role in the regulation of cell survival.
Pei, Wang   +5 more
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Epidemiology of Ischemic Stroke

Neurologic Clinics, 2016
Ischemic stroke is a heterogeneous multifactorial disorder recognized by the sudden onset of neurologic signs related directly to the sites of injury in the brain where the morbid process occurs. The evaluation of complex neurologic disorders, such as stroke, in which multiple genetic and epigenetic factors interact with environmental risk factors to ...
Albert S, Favate, David S, Younger
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Ischemic strokes and migraine

Neuroradiology, 1985
The coincidence of migraine and ischemic strokes is rare but unequivocal. Some of the cases described are recalled and the possible mechanisms discussed.
M G, Bousser, J C, Baron, J, Chiras
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Hypothermia and Ischemic Stroke

Current Treatment Options in Neurology, 2012
OPINION STATEMENT: The use of tissue plasminogen activator (tPA) is the major treatment method for acute ischemic stroke, but it reaches only a very limited number of stroke patients. Although neuroprotectants may be useful in stroke patients in principle, promising animal data have not yet been successfully transferred to stroke patients.
Rainer, Kollmar, Stefan, Schwab
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Autophagy and Ischemic Stroke

2020
Ischemic stroke refers to brain tissue ischemia, hypoxic necrosis, and brain softening caused by the interruption of the blood supply to the brain without adequate collateral circulation, thus resulting in neurological symptoms. Autophagy is activated in various cell types in the brain, such as neurons, glial cells, and microvascular cells, upon ...
Yanlin, Zhang   +2 more
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Genetics of ischemic stroke

Current Opinion in Neurology, 1995
Advances in the study of cerebrovascular disease suggest that many risk factors for stroke are under genetic influence. Epidemiologic studies show that parental and sibling histories of cerebral ischemic events are associated with an increased risk of stroke.
T J, DeGraba, L, Penix
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