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Autophagy and Ischemic Stroke

2020
Ischemic stroke refers to brain tissue ischemia, hypoxic necrosis, and brain softening caused by the interruption of the blood supply to the brain without adequate collateral circulation, thus resulting in neurological symptoms. Autophagy is activated in various cell types in the brain, such as neurons, glial cells, and microvascular cells, upon ...
Yanlin, Zhang   +2 more
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Genetics of ischemic stroke

Current Opinion in Neurology, 1995
Advances in the study of cerebrovascular disease suggest that many risk factors for stroke are under genetic influence. Epidemiologic studies show that parental and sibling histories of cerebral ischemic events are associated with an increased risk of stroke.
T J, DeGraba, L, Penix
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Ischemic Stroke Therapy

Annual Review of Medicine, 2002
▪ Abstract  Stroke is the most common life-threatening neurologic disease and the leading cause of serious long-term disability. The advent of new treatment options for selected patients suffering ischemic stroke (such as systemic administration of tissue plasminogen activator or catheter-guided intra-arterial thrombolysis), the structural ...
C, Stapf, J P, Mohr
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Phytochemicals in Ischemic Stroke

NeuroMolecular Medicine, 2016
Stroke is the second foremost cause of mortality worldwide and a major cause of long-term disability. Due to changes in lifestyle and an aging population, the incidence of stroke continues to increase and stroke mortality predicted to exceed 12 % by the year 2030.
Joonki, Kim   +5 more
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Ischemic stroke

Critical Care Medicine, 1994
To review selected aspects of the current treatment of acute ischemic stroke and provide an overview of basic neuroscience research in cerebral ischemia that may be applicable to future therapies.Selected recent references dealing with current therapy of acute stroke and basic neuroscience developments in cerebrovascular disease from the past several ...
R J, Wityk, B J, Stern
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Acute Ischemic Stroke

New England Journal of Medicine, 2020
Key Clinical Points Acute Ischemic Stroke Treatment for patients with acute ischemic stroke is guided by the time from the onset of stroke, the severity of neurologic deficit, and findings on neuro...
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Ischemic stroke prevention

Current Treatment Options in Neurology, 1999
More than 700,000 strokes occur annually in the United States--one every 40 to 50 seconds. Although stroke is one of the nation's most expensive diseases to treat, costing $41 billion per year, most strokes (perhaps as many as two thirds) are preventable.
, Chaturvedi, , Hickenbottom, , Levine
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Sonothrombolysis in Ischemic Stroke

Current Treatment Options in Neurology, 2013
Acute ischemic stroke remains one of the most devastating diseases when it comes to morbidity and mortality, not to mention the personal and economic burden that occurs in long-term. Intravenous thrombolysis with tissue plasminogen activator (tPA) is the only effective acute stroke therapy that improves outcome if given up to 4.5 hours from symptom ...
Kristian, Barlinn, Andrei V, Alexandrov
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Pericytes in Ischemic Stroke

2019
Recent stroke research has shifted the focus to the microvasculature from neuron-centric views. It is increasingly recognized that a successful neuroprotection is not feasible without microvascular protection. On the other hand, recent studies on pericytes, long-neglected cells on microvessels have provided insight into the regulation of ...
DALKARA, TURGAY   +2 more
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Ischemic stroke nanomedicine

Biomaterials
With the changes in lifestyle and the intensification of population aging, the incidence of stroke has been increasing annually, making it a global public health concern. Early diagnosis and precise treatment remain critical factors in improving patient outcomes.
Lan Luo   +4 more
openaire   +2 more sources

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