Results 1 to 10 of about 13,088 (227)

JAK3 as an Emerging Target for Topical Treatment of Inflammatory Skin Diseases. [PDF]

PLoS ONE, 2016
The recent interest and elucidation of the JAK/STAT signaling pathway created new targets for the treatment of inflammatory skin diseases (ISDs). JAK inhibitors in oral and topical formulations have shown beneficial results in psoriasis and alopecia ...
Ana Karina Alves de Medeiros, Reinhart Speeckaert, Eline Desmet, Mireille Van Gele, Sofie De Schepper, Jo Lambert   +5 more
doaj   +5 more sources

ISDS and Its Transformations [PDF]

Journal of International Economic Law, 2023
ABSTRACT Like the Journal of International Economic Law, which we celebrate with this special 25th Anniversary issue, investor-state dispute settlement (ISDS) came to life in the second half of the 1990s. The aim of this contribution is to ask whether ISDS has gone through any ‘transformation’, that is any ‘complete’ or ‘radical’ change,
exaly   +3 more sources

Intelligent real-life key-pixel image detection system for early Arabic sign language learners [PDF]

PeerJ Computer Science
Lack of an effective early sign language learning framework for a hard-of-hearing population can have traumatic consequences, causing social isolation and unfair treatment in workplaces.
Faten S. Alamri, Amjad Rehman, Sunusi Bala Abdullahi, Tanzila Saba   +3 more
doaj   +3 more sources

Assessing Sun Protection Policies in Texas School Districts Located in Counties With the Lowest and Highest Melanoma Risk: Content Analysis and Cross-Sectional Study [PDF]

Cancer Control
Introduction School policy can encourage sun safe habits, such as wearing hats and applying sunscreen. However, sun safety policies (SSP) have not been formally assessed for Texas independent school districts (ISDs), particularly in counties with the ...
Nabeel Ahmad MD, MSEd, Brooke Bartley MD, Stephanie Zhang BS, Madison M. Taylor MD, Karl Schrader BS, Kehe Zhang MS, Hung Quoc Doan MD, PhD, Cici Bauer PhD, MS, Kelly C. Nelson MD, Jennifer Cofer DrPH, MPH, CHES   +9 more
doaj   +2 more sources

Integrative Multi-Omics Analysis Reveals Critical Molecular Networks Linking Intestinal-System Diseases to Colorectal Cancer Progression [PDF]

Biomedicines
Background/Objectives: Colorectal cancer (CRC) frequently co-occurs with intestinal system diseases (ISDs), yet their molecular interplay remains poorly understood.
Shiliang Ji, Haoran Hu, Ruifang Zhu, Dongkai Guo, Yujing Liu, Yang Yang, Tian Li, Chen Zou, Yiguo Jiang, Guilai Liu   +9 more
doaj   +2 more sources

Development and validation of the Ibadan Simplified Developmental Screening chart [PDF]

Frontiers in Pediatrics, 2023
BackgroundDevelopmental assessment remains an integral part of the routine evaluation of the wellbeing of every child. Children in resource-poor countries are not routinely assessed for signs of developmental delay and developmental disorders are ...
I. A. Lagunju, Y. Adeniyi, A. E. Orimadegun, D. Fernandez-Reyes   +3 more
doaj   +2 more sources

Use of Pharmacogenetics to Optimize Immunosuppressant Therapy in Kidney-Transplanted Patients

Biomedicines, 2022
Immunosuppressant drugs (ISDs) are routinely used in clinical practice to maintain organ transplant survival. However, these drugs are characterized by a restricted therapeutic index, a high inter- and intra-individual pharmacokinetic variability, and a ...
Valentina Urzì Brancati, Carmelo Scarpignato, Letteria Minutoli, Giovanni Pallio   +3 more
doaj   +1 more source

Is It Time to Say Farewell to the ISDS System?; Comment on “The Trans-Pacific Partnership: Is It Everything We Feared for Health?” [PDF]

International Journal of Health Policy and Management, 2017
Investor-state dispute settlement (ISDS) continues to plague health-oriented government regulation. This is particularly reflected in recent challenges to tobacco control measures through bilateral investment agreements.
Raphael Lencucha
doaj   +1 more source

Influence of In-Situ Oil Sands Development on Caribou (Rangifer tarandus) Movement. [PDF]

PLoS ONE, 2015
In-situ oil sands development (ISD) involves a network of facilities, wells, roads and pipelines to extract and transport subsurface bitumen. This technology is rapidly expanding and there is uncertainty whether ISDs restrict animal movement, leading to ...
Tyler Muhly, Robert Serrouya, Eric Neilson, Haitao Li, Stan Boutin   +4 more
doaj   +1 more source

The Right of Access to Water in the Context of Investment Disputes in Argentina: Urbaser and Beyond

Utrecht Law Review, 2020
The privatisation of water through foreign investment has become a common occurrence throughout the world. In developing economies like Argentina, many people depend on their water supply from private companies, including foreign investors.
Yulia Levashova
doaj   +1 more source