Results 151 to 160 of about 491,178 (273)

Dose- and Time-Dependent Transcriptional Response of Ishikawa Cells Exposed to Genistein.

Toxicological Sciences, 2016
J. Naciff, Zubin S Khambatta, G. Carr, J. Tiesman, D. Singleton, Sohaib A. Khan, G. Daston   +6 more
semanticscholar   +1 more source

Corticotropin‐Releasing Hormone (CRH) in Murine Narcolepsy: What Do Genetic and Immune Models Tell Us?

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou, S. Melzi, A. L. Morel, B. Georges, T. E. Scammell, G. J. Lammers, R. Fronczek, C. Peyron   +7 more
wiley   +1 more source

Intraspecific Variation in Reproductive Aspects of Female Soldier Crabs, Mictyris guinotae, Between the River Mouth and Upper Reach Habitats

Marine Ecology, EarlyView.
ABSTRACT The soldier crab, Mictyris guinotae, is a dominant intertidal crustacean associated with sand flats in the vicinity of the Urauchi River estuary on Iriomote Island, Japan. We compared various aspects of its reproductive biology at two sites (the river mouth and upper reach) on exposed bare sand flats 300 m and 3000 m upstream from the mouth ...
Masaki Jinno, Wataru Doi, Akira Mizutani, Hiroyoshi Kohno   +3 more
wiley   +1 more source

A quality improvement initiative to reduce inappropriate plasma transfusions across community hospitals in the Niagara region

Vox Sanguinis, EarlyView.
Abstract Background and Objectives Plasma transfusion is indicated for patients with coagulopathy and active bleeding or those undergoing major surgery. Appropriate use is defined by an international normalized ratio (INR) >1.7 and a dose of 3–4 units for adults.
Krista Walter, Ismael Ahmad, Tanja Groeneveld, Ankush Chander, Mohammad Refaei   +4 more
wiley   +1 more source

Plain Language Summary Publication: Efficacy and safety of rimegepant for the preventive treatment of migraine in Japan: A double‐blind, randomized controlled trial

Headache: The Journal of Head and Face Pain, EarlyView.
Shigekazu Kitamura, Yasuhiko Matsumori, Toshimasa Yamamoto, Tomofumi Ishikawa, Yuko Hoshino, Hiroki Yoshimatsu, Alexandra Thiry, Akio Arakawa, Robert Croop, Terence Fullerton, Fumihiko Sakai, Takao Takeshima   +11 more
wiley   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

Experimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris, Anton Trask‐Marino, Alemayehu Jufar, Ashenafi H. Betrie, Adam Southon, Sally G. Hood, Rinaldo Bellomo, Abraham H. Hulst, Clive N. May, Connie P. C. Ow, Yugeesh R. Lankadeva   +10 more
wiley   +1 more source

Mapping the variability of in vivo rat uterine electrical properties throughout the oestrous cycle

Experimental Physiology, EarlyView.
Abstract After reaching sexual maturity, uterine function is driven by cyclical variations in hormone levels. The electrical and mechanical activity in the uterus varies during the menstrual cycle, contributing to essential functions such as sperm transport and shedding the menstrual lining.
Mathias W. Roesler, Amy S. Garrett, Leo K. Cheng, Alys R. Clark   +3 more
wiley   +1 more source

Whole‐body hot water immersion effect on cerebral haemodynamics and subsequent cerebrovascular reactivity to carbon dioxide

Experimental Physiology, EarlyView.
Abstract To test the hypothesis that hot water immersion (HWI) improves cerebrovascular function via shear‐mediated mechanisms, this study determined cerebrovascular reactivity to carbon dioxide (CVRCO2${\mathrm{CV}}{{\mathrm{R}}_{{\mathrm{C}}{{\mathrm{O}}_2}}}$) before and after 60 min of 39°C HWI and a 21°C air control (CON) in 15 healthy ...
Samuel F. Leaney, Ester Tommasini, Guto W. Hughes, Alison M. Shepherd, Nyah D. Kingdon, Justin S. Lawley, Geoff B. Coombs, Jonathan P. Moore, Samuel J. Oliver   +8 more
wiley   +1 more source

Mitonucleons formed during differentiation of Ishikawa endometrial cells generate vacuoles that elevate monolayer syncytia: Differentiation of Ishikawa domes, Part 1

, 2016
H. Fleming
semanticscholar   +1 more source

Artemisinin triggers a G1 cell cycle arrest of human Ishikawa endometrial cancer cells and inhibits cyclin-dependent kinase-4 promoter activity and expression by disrupting nuclear factor-&kgr;B transcriptional signaling

Anti-Cancer Drugs, 2014
K. Q. Tran, Antony S. Tin, G. Firestone
semanticscholar   +1 more source