Results 101 to 110 of about 1,850,478 (263)

An electromechanical Ising machine

, 2015
Solving intractable mathematical problems in simulators composed of atoms, ions, photons or electrons has recently emerged as a subject of intense interest. Here we extend this concept to phonons that are localised in spectrally pure resonances in an electromechanical system which enables their interactions to be exquisitely fashioned via electrical ...
Mahboob, I., Yamaguchi, H.
openaire   +2 more sources

A Real‐Data‐Driven Framework for Evaluating Differential Transcript Usage Methods Across Long‐Read Bulk, Single‐Cell, and Spatial Transcriptomics

Advanced Science, EarlyView.
Grounded in real biological RNA‐seq data, the framework benchmarks ten differential transcript usage (DTU) methods across short‐read bulk, long‐read bulk, long‐read single‐cell, and long‐read spatial transcriptomics. By integrating reference transcript sets with ranked DTU results, the Transcript Set Enrichment Score (TSES) identifies data‐type ...
Chenxing Zhang, Jun Liu, Qi Zhao, Huilong Yin, Angang Yang, Minhua Zheng, Rui Zhang   +6 more
wiley   +1 more source

On-demand photonic Ising machine with simplified Hamiltonian calculation by phase encoding and intensity detection

Communications Physics
The photonic Ising machine is a new paradigm of optical computing that takes advantage of the unique properties of light wave propagation, parallel processing, and low-loss transmission.
Jiayi Ouyang, Yuxuan Liao, Zhiyao Ma, Deyang Kong, Xue Feng, Xiang Zhang, Xiaowen Dong, Kaiyu Cui, Fang Liu, Wei Zhang, Yidong Huang   +10 more
doaj   +1 more source

Nonlinear Quantum Effects Drive Grotthuss Proton Conduction in Structured Electrolytes Based on Deep Eutectic Solvents

Advanced Science, EarlyView.
We demonstrate that the inverse relationship between viscosity and conductivity in structured electrolytes can be circumvented by leveraging their hydrogen bonding networks for Grotthuss proton transport. Using a mixture of imidazole and levulinic acid, we show that the existence of extended hydrogen‐bonded chains that can rapidly reorient result in ...
Benworth B. Hansen, Michael S. Chen, Giselle de A. L. e Souza, Kaylie Glynn, Alan Robledo, Emilia Pelegano‐Titmuss, Katherine Hightower, Miguel Muñoz, Rathiesh Pandian, Clemens Burda, Aikaterini Sanida, Mark Dadmun, Burcu E. Gurkan, Steve G. Greenbaum, Mark E. Tuckerman, Joshua R. Sangoro   +15 more
wiley   +1 more source

Hardware‐Native Gaussian Sampling With Probabilistic Ising Machines for Modern Communication Paradigms [PDF]

Advanced science
Probabilistic Ising machines are introduced as hardware‐native Gaussian samplers for edge communication workloads. Tunable variance and sampling density enable accurate distributions for Falcon‐class post‐quantum signatures and diffusion‐based semantic communication.
Rodrigues D, Grimaldi A, Volpe D, Bao Y, Yang S, Grassucci E, Siracusano G, Chiappini M, Carpentieri M, Yang H, Finocchio G.   +10 more
europepmc   +2 more sources

Computing the Cramer-Rao bound of Markov random field parameters: Application to the Ising and the Potts models [PDF]

, 2013
This letter considers the problem of computing the Cramer–Rao bound for the parameters of a Markov random field. Computation of the exact bound is not feasible for most fields of interest because their likelihoods are intractable and have intractable ...
Batatia, Hadj, Pereyra, Marcelo Alejandro, Hadj Batatia, Nicolas Dobigeon, Jean-yves Tourneret, Dobigeon, Nicolas, Tourneret, Jean-Yves, Marcelo Pereyra, Pereyra, Marcelo   +8 more
core   +1 more source

CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs

Advanced Science, EarlyView.
In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang, Zhenhua Hu, Jiali Liao, Lijun Huang, Jinyu Liu, Chen Tu, Yuchen Li, Lulu Xie, Shilei Bi, Xiaobo Fang, Jingsi Chen, Lili Du, Wei Sun, Haibin Wang, Shuang Zhang, Dunjin Chen, Zhaowei Tu   +16 more
wiley   +1 more source

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

An Integrated All‐Optical Ising Machine with Unlimited Spin Array Size and Coupling

Advanced Photonics Research
Artificial spin systems are used to solve combinatorial optimization problems by mapping them to the ground state search of the Ising model. Ising machines of various designs, in fields as diverse as photonics and electronics, have been proposed and ...
Yuchi Lan, Guanyu Chen, Yuan Gao, Wujie Fu, Aaron J. Danner   +4 more
doaj   +1 more source

An Area-Efficient Continuous-Time Ising Machine Featuring Dynamic Threshold Annealing

IEEE Access
Recently, Ising machines have received rising attention as efficient alternatives for solving combinatorial optimization problems (COPs), compared to von Neumann architectures with high power consumption and prolonged latencies. While prior discrete-time
Yufeng Wu, Xiaofeng Li, Jiayin Song, Yi Zhan, Shushan Qiao   +4 more
doaj   +1 more source