Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
Neuronal spiking in the mammalian forebrain is dominated by a heterogeneous ground state. [PDF]
Levenstein D +10 more
europepmc +1 more source
ABSTRACT Background Elinzanetant, a novel, dual neurokinin‐targeted therapy, has been approved in various geographies for the treatment of moderate‐to‐severe vasomotor symptoms (VMS) associated with menopause. Objective To compare the efficacy of elinzanetant with non‐hormonal pharmaceutical treatments (nHT) in alleviating VMS.
Piotr Wojciechowski +8 more
wiley +1 more source
Do Hyperlaxity, Sex, and Number of Dislocations Have an Impact on the Characteristics of Patients With Chronic Anterior Shoulder Instability? [PDF]
Barret H +4 more
europepmc +1 more source
Monetary Policy, Investor Sentiment and Stock Price Bubble: Evidence From China
ABSTRACT The empirical results indicate that an increase in interest rates may stimulate a significant and persistent stock price bubble, which is consistent with rational asset price bubble theory. This finding suggests that central banks should implement anti‐turbulent monetary policy with caution, since inappropriate tightening may unintentionally ...
Jiahao Gong +3 more
wiley +1 more source
The iCre-DTA176 Mouse Exhibits Canonical Spontaneous Network Activity Associated With Retinal Degeneration. [PDF]
Fifield-Smith SW +5 more
europepmc +1 more source
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
Augmented and prematurely occurring H-reflex recovery curve shows enhanced spinal network excitability in ALS patients when employing the double stimulation paradigm. [PDF]
Wölk SA, Prudlo J, Walter U, Patejdl R.
europepmc +1 more source
Place Matters at Work: A Systematic Review of Workplace Attachment and Environmental Factors
ABSTRACT The topic of workplace attachment has garnered significant attention in academic studies since the early 2010s. However, due to its inherently interdisciplinary scope, research on workplace attachment remains notably fragmented and lacks cohesion, resulting in numerous unresolved questions.
Rubinia Celeste Bonfanti +3 more
wiley +1 more source

