Results 41 to 50 of about 237,326 (288)

Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein

open access: yesJournal of Lipid Research, 2013
Therapeutic agents that suppress apolipoprotein B (apoB) and microsomal triglyceride transfer protein (MTP) levels/activity are being developed in the clinic to benefit patients who are unable to reach target LDL-C levels with maximally tolerated lipid ...
Richard G. Lee   +8 more
doaj   +1 more source

Target Optimisation Studies for Surface Muon Production [PDF]

open access: yes, 2014
The current paper discusses possible designs for a stand alone muon target for MuSR studies of condensed matter science. Considering the ISIS 7 mm graphite target as a reference, Geant4 simulations have been performed in order to optimize the target ...
Bungau, Adriana   +4 more
core   +2 more sources

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

open access: yesAdvanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali   +4 more
wiley   +1 more source

Interspike intervals within retinal spike bursts combinatorially encode multiple stimulus features.

open access: yesPLoS Computational Biology, 2020
Neurons in various regions of the brain generate spike bursts. While the number of spikes within a burst has been shown to carry information, information coding by interspike intervals (ISIs) is less well understood.
Toshiyuki Ishii, Toshihiko Hosoya
doaj   +1 more source

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

open access: yesAdvanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin   +18 more
wiley   +1 more source

ISIS in America: A Sociohistorical Analysis [PDF]

open access: yes, 2017
During the summer of 2014, the terrorist organization Islamic State (commonly referred to as Islamic State in Iraq and Syria, or ISIS) garnered international attention after its unprecedented territorial acquisitions and violence in the Middle East ...
Ratcliff, Kathryn Joanne
core   +2 more sources

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan   +17 more
wiley   +1 more source

Epidemic growth and Griffiths effects on an emergent network of excited atoms

open access: yesNature Communications, 2021
The emergent excitation dynamics of an ultracold gas of Rydberg atoms exhibits features analogous to epidemic spreading on networks. Wintermantel et al.
T. M. Wintermantel   +7 more
doaj   +1 more source

COVER, DAFTAR ISI

open access: yesTeknobiz : Jurnal Ilmiah Program Studi Magister Teknik Mesin, 2021
COVER, DAFTAR ...
openaire   +1 more source

XOR‐Logic Phase Coding Programmable Metasurface for Low Power‐Consumption Systems

open access: yesAdvanced Science, EarlyView.
By leveraging XOR logic, the biasing‐network complexity of 2D programmable metasurfaces is reduced from m×n to m+n through efficient row‐column control. This enables versatile functions including beam deflection and beamforming, facilitating applications in wireless communications and beyond.
Ruichao Zhu   +10 more
wiley   +1 more source

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