Results 21 to 30 of about 837,284 (297)
Island Studies Journal 1(2), Book Reviews
Island Studies Journal, 2006 _Island Studies Journal_, 1(2), Book reviews.
Island Studies Journal
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Architecture Image Studies Scientific Journal, 2021 The ‘Making Genus’ project comes as a multi-faceted response to an unassuming, mono-directional quest – creating genderless utopia. Spanning across several mediums of expression such as graphics, the moving image and fiction writing, the work ...
Dariana Nistor
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Annals of the American Association of Geographers, 2023 Islandness is a contested concept, not just between disciplines but also cultures, entangled with what islands, island studies, and island identity are understood to be. The purpose of this article is to explore some of these different meanings, without necessarily unifying or reconciling them, with the aim of keeping multiple understandings of ...
Aideen Foley +11 more
openaire +4 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Architecture Image Studies Scientific Journal, 2021 This text offers a writerly experiment aimed at developing a possible method of critical speculative fiction. The subject is an imaginary island modelled on the Cycladic island of Amorgos, Greece, which is depicted here as an all-encompassing design ...
Marko Jobst
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Island Transport Challenges: Four Island Jurisdictions; Seven Island Perspectives
Island Studies JournalIsland transport systems are as unique as the islands themselves, shaped by geography, politics, and community needs. Transport development raises key questions: does increased connectivity enhance or diminish islandness? Can large-scale projects balance economic goals with environmental sustainability and community needs?
Abraham Leung, Stefan Baumeister
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source