Results 41 to 50 of about 2,849,118 (307)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Island Studies Journal 3(1), Book Reviews

open access: yesIsland Studies Journal, 2008
_Island Studies Journal_ 3(1), Book ...
Island Studies Journal
doaj   +1 more source

Unmet Needs: Superstorm Sandy and Immigrant Communities in the Metro New York Area [PDF]

open access: yes, 2012
[Excerpt] More than a month after Superstorm Sandy, many New Yorkers continue to struggle with the devastation of their homes, neighborhoods and livelihoods. One group that has faced particular challenges, but has received little attention are the region’
Make the Road New York
core   +1 more source

Shear Alfven wave continuous spectrum within magnetic islands

open access: yes, 2010
The radial structure of the continuous spectrum of shear Alfven waves is calculated in this paper within the separatrix of a magnetic island. Geometrical effects due to the noncircularity of the flux surface's cross section are retained to all orders. On
Biancalani, Alessandro   +3 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3 - Implications for the evolution of staphylococcal pathogenicity islands [PDF]

open access: yes, 2002
We describe the complete sequence of the 15.9-kb staphylococcal pathogenicity island 3 encoding staphylococcal enterotoxin serotypes B, K, and Q. The island, which meets the generally accepted definition of pathogenicity islands, contains 24 open reading
Kapur, Vivek   +5 more
core  

Dynamic Island Model based on Spectral Clustering in Genetic Algorithm

open access: yes, 2017
How to maintain relative high diversity is important to avoid premature convergence in population-based optimization methods. Island model is widely considered as a major approach to achieve this because of its flexibility and high efficiency.
Ellisy, John   +3 more
core   +1 more source

Pyroclastic deposits and volcanic history of Mayor Island [PDF]

open access: yes, 1981
The emergent summit of Mayor Island, Bay of Plenty, New Zealand, is a peralkaline rhyolite volcano constructed by: a sequence of lava flows, the Tutaretare Rhyolite Formation new; and pyroclastic deposits, the Oira Pyroclastite Formition (new).
Briggs, Roger M.   +2 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Island Studies Journal, 2(1), Book Reviews

open access: yesIsland Studies Journal, 2007
_Island Studies Journal_, 2(1), Book ...
Island Studies Journal
doaj   +1 more source

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