Results 41 to 50 of about 1,429,184 (280)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
A diversidade de plantas está associada à heterogeneidade de habitats, à ampla distribuição de espécies, ao pulso de inundação que podem estar sendo controlados pela dinâmica fluvial e diferenças na origem geomorfológica.
Solange Kimie Ikeda Castrillon +3 more
doaj +1 more source
Sustainability: Suspicions Concerning Attainability, with Particular Reference to the Pacific [PDF]
Sustainability and unsustainability are frequently deployed in discussions of intended, predicted and observed changes occurring in or impacting on Pacific islands societies.
Wolfers, Edward
core +3 more sources
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
Nanodot to Nanowire: A strain-driven shape transition in self-organized endotaxial CoSi2 on Si (100)
We report a phenomenon of strain-driven shape transition in the growth of nanoscale self-organized endotaxial CoSi2 islands on Si (100) substrates. Small square shaped islands as small as 15\times15 nm2 have been observed.
Anupam Roy +8 more
core +1 more source
Adsorbate-induced Restructuring of Pb mesas Grown on Vicinal Si(111) in the Quantum Regime [PDF]
Using scanning tunneling microscopy and spectroscopy, we demonstrate that the adsorption of a minute amount of Cs on a Pb mesa grown in the quantum regime can induce dramatic morphological changes of the mesa, characterized by the appearance of populous ...
Eisele, Holger +6 more
core +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Clean water quality/water sources are critical factors in preventing diarrhea, especially in island areas that often face challenges of limited access and infrastructure to provide adequate clean water.
Nur Ariati Mukharomah +1 more
doaj +1 more source
Marine soft-sediments sustain functionally important benthic assemblages that are critical for remineralization of organic matter and supply of nutrients to the water column.
Aiswarya Gopal +8 more
doaj +1 more source
Physical and Biogeochemical Studies in the Subtropical and Tropical Atlantic [PDF]
Maria S. Merian Cruise Report MSM18/L2 Cruise No.
Alevara Martinez, D. +21 more
core

