Results 51 to 60 of about 2,280,143 (327)

The impact of global environmental change on transport in Malta [PDF]

, 2015
This study addresses the impact of global environmental change, speci fically on transport in the Maltese Islands, with special attention to the economic implications of changes on: (i) employment, (ii) product or service growth/decline, (iii ...
Attard, Maria
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Avaliação da diversidade arbórea das ilhas do rio Paraguai na região de Cáceres, Pantanal Matogrossense, Brasil Assessment of tree diversity on the islands of the Paraguay River, in the Caceres region, Pantanal, Brazil

Acta Botânica Brasílica, 2011
A diversidade de plantas está associada à heterogeneidade de habitats, à ampla distribuição de espécies, ao pulso de inundação que podem estar sendo controlados pela dinâmica fluvial e diferenças na origem geomorfológica.
Solange Kimie Ikeda Castrillon, Carolina Joana da Silva, José Ricardo Castrillon Fernandez, Andrea Kyoko Ikeda   +3 more
doaj   +1 more source

Nanodot to Nanowire: A strain-driven shape transition in self-organized endotaxial CoSi2 on Si (100)

, 2012
We report a phenomenon of strain-driven shape transition in the growth of nanoscale self-organized endotaxial CoSi2 islands on Si (100) substrates. Small square shaped islands as small as 15\times15 nm2 have been observed.
Anupam Roy, B. N. Dev, Chen L. J., Debolina Das, Goswami D. K., J. C. Mahato, P. V. Satyam, R. Batabyal, R. R. Juluri   +8 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Sustainability: Suspicions Concerning Attainability, with Particular Reference to the Pacific [PDF]

, 2017
Sustainability and unsustainability are frequently deployed in discussions of intended, predicted and observed changes occurring in or impacting on Pacific islands societies.
Wolfers, Edward
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Clean Water For Small Islands In Indonesia: Case Study Of Child Diarrhea In Kelapa And Kelapa Dua Islands, Kepulauan Seribu

Jurnal Riset Kesehatan
Clean water quality/water sources are critical factors in preventing diarrhea, especially in island areas that often face challenges of limited access and infrastructure to provide adequate clean water.
Nur Ariati Mukharomah, Umar Fahmi Achmadi   +1 more
doaj   +1 more source

Distinctive Community Patterns With Exceptional Diversity of Polychaetes Around a Tectonically Active Archipelago in the Tropical Indian Ocean

Frontiers in Marine Science, 2020
Marine soft-sediments sustain functionally important benthic assemblages that are critical for remineralization of organic matter and supply of nutrients to the water column.
Aiswarya Gopal, K. U. Abdul Jaleel, Usha V. Parameswaran, V. N. Sanjeevan, A. V. Saramma, Anilkumar Vijayan, N. Saravanane, G. V. M. Gupta, M. Sudhakar   +8 more
doaj   +1 more source