Results 161 to 170 of about 8,058 (237)

Omics GWAS: A Multi‐Omics Integrative Analysis Platform for Genome‐Wide Association Studies

Med Research, EarlyView.
ABSTRACT With the rapid advancement of genome‐wide association studies (GWAS), downstream analyses of GWAS data have become essential for elucidating the genetic mechanisms that underlie complex diseases. However, current post‐GWAS analyses face numerous challenges, including heterogeneous data formats, challenges in multi‐omics integration, and ...
Xu Zhang, Kailai Li, Yasi Zhang, Cenwen Liu, Shunyi Huang, Yingzhao Jin, Yugeng Gao, Quan Cheng, Yunyun Mei   +8 more
wiley   +1 more source

Energetic and Spectroscopic Insights into the C₃H₆O₂ Isomer Family for Astrochemical Purposes. [PDF]

ACS Earth Space Chem
Savarese A, Alessandrini S, Melosso M, Panizzi G, Nonne M, Bizzocchi L, Puzzarini C.   +6 more
europepmc   +1 more source

Quantifying Cardiac, Respiratory, and Low Frequency Components of CSF Motion From fMRI Inflow Effects

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Cerebrospinal fluid (CSF) flow oscillations have emerged as a potentially important marker related to brain clearance, but their acquisition often relies on specialized imaging MRI sequences. The purpose of this work was to enable quantitative assessment of CSF flow associated with cardiac, respiratory, and low‐frequency cycles using ...
Pontus Söderström, Cecilia Björnfot, Britt M. Andersson, Jan Malm, Anders Eklund, Anders Wåhlin   +5 more
wiley   +1 more source

Pyrrole without Life: Reaction of Aminomethylene with the Propargyl Radical. [PDF]

J Phys Chem Lett
McClish R, Schleier D, Kamer J, Kasper T, Hemberger P, Bodi A, Bouwman J.   +6 more
europepmc   +1 more source

A Sub‐Microsecond Switch Enabling SWIFT 23Na Imaging at 10.5 T

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To enable sodium SWIFT imaging, which is a zero‐echo time imaging technique, at ultra‐high magnetic fields through the development of custom electronics hardware, and to showcase this capability with in vivo imaging results. Methods The custom hardware developed consists of a high‐speed optical trigger with 10 ns resolution, an in‐bore
Russell L. Lagore, Simon Schmidt, Edward J. Auerbach, Naoharu Kobayashi, Christoph Schildknecht, Steen Moeller, Elnaz Mahmoudi Mahmoudalilou, Štefan Zbýň, Jutta Ellermann, Gregor Adriany, Gregory J. Metzger   +10 more
wiley   +1 more source

Decoding exon inclusion in the human brain reveals more divergent splicing mechanisms in neurons than glia. [PDF]

Genome Biol
Michielsen L, Hsu J, Joglekar A, Belchikov N, Reinders MJT, Tilgner HU, Mahfouz A.   +6 more
europepmc   +1 more source

Interplanetary frontiers: terraforming from an invasion science perspective

Oikos, EarlyView.
The pursuit of a multi‐planetary existence represents one of humanity's greatest frontiers. If applied justly, it offers an opportunity to extend its civilization's lifespan amid escalating sustainability crises on Earth. One approach increasingly gaining traction is terraforming, a hitherto theoretical ecological and evolutionary experiment revolving ...
Teun Everts, Ronaldo Sousa, Phillip J. Haubrock   +2 more
wiley   +1 more source

Lanthanide Tetrabromoterephthalates: Promotion of Cycloaddition Reactions of Carbon Dioxide without Preactivation, Solvent, and Co-Catalyst at Ambient Pressure through Structural Design. [PDF]

Inorg Chem
Sinchow M, Chuasaard T, Chiangraeng N, Bird SA, Nimmanpipug P, Yoshinari N, Rujiwatra A.   +6 more
europepmc   +1 more source

The transformative potential of artificial intelligence in pediatric medicine: Current applications, methodological challenges, and future directions

Pediatric Investigation, EarlyView.
Artificial intelligence (AI) offers transformative potential for paediatric diagnosis and treatment, yet implementation faces unique challenges, including data scarcity, algorithmic bias, and children's developmental physiology. This review examines current applications and charts a path toward transparent, equitable, and trustworthy AI in child health.
Ruisong Wang, Xiaoman Ding, Wanyue Zhang, Tieliu Shi   +3 more
wiley   +1 more source

Non-equilibrium preparation of (<i>E</i>)-phosphinimine (HPNH, X¹A') - a precursor to prebiotic phosphorylating agents. [PDF]

Chem Sci
Wang J, Sun BJ, Bergantini A, Wang Z, McAnally M, Marks JH, Chang AHH, Eckhardt AK, Kaiser RI.   +8 more
europepmc   +1 more source