NEW APPROACH TO TREATMENT OF ONCOLOGICAL DISEASES
Oncological diseases are the second leading cause of deaths. Immune system disorders and enzymatic imbalances undoubtedly play a role in the development of tumors.
V.G. Dorofeichuk +2 more
doaj +4 more sources
Identification of mouse H-2 antigens by mixed lymphocyte culture in the presence of PHA. 3. Blastformation of mouse lymphocytes according to the difference in non- H-2 antigens [PDF]
It has been demonstrated that by the mixed cultures in the presence of PHA the combination of those cells whose H-2 antigens differ from each other shows a higher rate and more significant difference of blastformation than in the combination where non-H ...
Kaneda, Shoken
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The Expression of the Epithelial Blood-group Substances: Normal and Malignant Tissues [PDF]
The blood-group isoantigens are macromolecules localized to the plasma membranes of certain epithelial tissues.2,11-15 These substances are not detectable on the epithelium once it has undergone malignant transformation.2,9,13 Results of this ...
C.T. Hanks, D.E. Lopatin, D.I. George
core +2 more sources
Employing the indirect immunoperoxidase technique, monoclonal antisera against blood group antigens A and B were used to localize the corresponding tissue isoantigens in normal ureter and transitional cell carcinoma of the ureter and renal pelvis in 29 ...
E P Allhoff +3 more
core +1 more source
Allogeneic inhibitory activity of regional lymph node cells in the mouse isografted with methylcholanthrene-induced tumor [PDF]
In mouse bearing progressive cancer a decrease was present in the allogeneic inhibitory activity of T-lymphocytes, which constitutes the core of immunological surveillance system in mammalians.
Orita, Kunzo +4 more
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Intratumor heterogeneity is a major problem in immunodiagnosis and treatment of carcinomas. To elucidate the well-known heterogeneity in transitional-cell carcinomas of the ability to express blood group ABO isoantigens, a stereological estimate of the ...
T F Orntoft, K Nielsen
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Are blood group isoantigens lost from malignant prostatic epithelium? Immunohistochemical support for the preservation of the H isoantigen [PDF]
Previous studies while demonstrating the presence of blood group isoantigens on normal prostatic epithelium have failed to identify such antigens on malignant prostatic tissue. Using a series of blood group specific monoclonal antibodies directed towards the A, B, H and Y antigens we have reinvestigated blood group isoantigen expression in both benign ...
P, Vowden +3 more
openaire +2 more sources
Fluorometric quantitation of fluorescein-coupled antibodies attached to the cell membrane.
A method was devised which allows the measurement, by direct and indirect fluorescence assay, of the binding of fluorescein-coupled antibodies directed against cell-membrane antigens.
Strom, R +4 more
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ABO(H) isoantigens in bladder tumours : a new technique of quantitative analysis
Bladder tumours are the second most common urological malignancy seen and twenty-five percent of all superficial tumours ultimately become invasive. -- The Specific Red Cell Adherence Test (SRCA) appears most promising with a potential to predict which ...
Srinivas, V.(Varadarchary)
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Blood group isoantigens can be demonstrated immune-histologically on normal urothelium of the urinaty bladder by means of the specific red cell adherence test. In preneoplastic and reactive changes of the urothelium and in dysplasia and carcinoma in situ,
Jakse, G., Hofstädter, Ferdinand
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