Results 91 to 100 of about 18,230 (249)

RNA-seq data and surprisal analysis of icl mutant and control strain of the green microalga Chlamydomonas reinhardtii during day/night cycles

Data in Brief, 2018
The data presented in this article are associated to the research article “Surprisal analysis of the transcriptomic response of the green microalga Chlamydomonas to the addition of acetate during day/night cycles” (Willamme et al., 2018) [1].
R. Willamme, K.A. Bogaert, F. Remacle, C. Remacle   +3 more
doaj   +1 more source

Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays.

, 2013
Campylobacter jejuni is the leading cause of human bacterial gastroenteritis worldwide, but source attribution of the organism is difficult. Previously, DNA microarrays were used to investigate isolate source, which suggested a non-livestock source of ...
Altschul, Brandl, Champion, Dingle, Dingle, Dorrell, Ethelberg, Francisco, French, Gundogdu, Harris, Hepworth, Hepworth, Hinchliffe, Howard, Huelsenbeck, Jensen, Jorgensen, Joshua, Kalendar, Karenlampi, Katoh, Katoh, Kemp, Kim, Kim, King, Kwan, Kwan, Manning, McCarthy, Mellmann, Miller, Moen, Murphy, Ogden, On, Park, Pearson, Petersen, Ronquist, Rosef, Rosef, Sails, Sanad, Schonberg-Norio, Skirrow, Skirrow, Stabler, Staden, Staden, Taboada, Taboada, Tam, Tam, Wilson   +55 more
core   +1 more source

Role of central metabolism in the osmoadaptation of the halophilic bacterium chromohalobacter salexigens [PDF]

, 2013
Bacterial osmoadaptation involves the cytoplasmic accumulation of compatible solutes to counteract extracellular osmolarity. The halophilic and highly halotolerant bacterium Chromohalobacter salexigens is able to grow up to 3 M NaCl in a minimal medium ...
Argandoña Bertrán, Montserrat, Bernal, Vicente, Csonka, Laszlo N., Cánovas, Manuel, Iborra, José Luis, Nieto Gutiérrez, Joaquín José, Pastor, José M., Salvador de Lara, Manuel, Sevilla, Ángel, Vargas Macías, Carmen   +9 more
core   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, Volume 103, Issue 7, Page e436-e455, November 2025.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

The endocytosis gene END3 is essential for the glucose-induced rapid decline of small vesicles in the extracellular fraction in Saccharomyces cerevisiae

Journal of Extracellular Vesicles, 2014
Background: Protein secretion is a fundamental process in all living cells. Gluconeogenic enzymes are secreted when Saccharomyces cerevisiae are grown in media containing low glucose.
Bennett J. Giardina, Kathryn Stein, Hui-Ling Chiang   +2 more
doaj   +1 more source

Understanding the impact of the cofactor swapping of isocitrate dehydrogenase over the growth phenotype of Escherichia coli on acetate by using constraint-based modeling. [PDF]

PLoS ONE, 2018
It has been proposed that NADP+-specificity of isocitrate dehydrogenase (ICDH) evolved as an adaptation of microorganisms to grow on acetate as the sole source of carbon and energy. In Escherichia coli, changing the cofactor specificity of ICDH from NADP+
Erick Armingol, Eduardo Tobar, Ricardo Cabrera   +2 more
doaj   +1 more source

Elucidation of Beta-Oxidation Pathways in Ralstonia Eutropha H16 by Examination of Global Gene Expression [PDF]

, 2010
Ralstonia eutropha H16 is capable of growth and polyhydroxyalkanoate production on plant oils and fatty acids. However, little is known about the triacylglycerol and fatty acid degradation pathways of this bacterium. We compare whole-cell gene expression
Brigham, Christopher J., Budde, Charles F., Holder, Jason W., Mahan, Alison E., Rha, ChoKyun, Sinskey, Anthony J., Zeng, Qiandong   +6 more
core   +2 more sources

Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories

Advanced Science, Volume 12, Issue 40, October 27, 2025.
This review presents state‐of‐the‐art metabolic engineering strategies to balance microbial cell growth and product synthesis in biorefineries. It surveys pathway engineering, dynamic genetic circuits, orthogonal control systems, synthetic microbial consortia, and fermentation optimization, alongside integrative modeling approaches.
Linxia Liu, Dongqin Ding, Huiying Wang, Xinyi Ren, Sang Yup Lee, Dawei Zhang   +5 more
wiley   +1 more source

Exploring prospects of novel drugs for tuberculosis [PDF]

, 2012
Tuberculosis remains a disease with an enormous impact on public health worldwide. With the continuously increasing epidemic of drug-resistant tuberculosis, new drugs are desperately needed. However, even for the treatment of drug-sensitive tuberculosis,
Grobusch, M. P., Janssen, S., Jayachandran, R., Khathi, L., Pieters, J., Zinsstag, J.   +5 more
core   +1 more source

Epi‐Immunotherapy in Cancer Treatment: Mechanisms, Clinical Progress, and Future Directions

Cancer Innovation, Volume 4, Issue 5, October 2025.
Epigenetic regulation of tumor immune evasion and synergistic anticancer strategies via epigenetic‐immunotherapy integration. ABSTRACT Cancer immunotherapy is a groundbreaking therapeutic strategy, yet it continues to face significant challenges, including limited overall response rates and treatment resistance.
Nannan Lu, Guanghua Rong, Weidong Han
wiley   +1 more source