Results 151 to 160 of about 37,394 (195)

Active site modification of isocitrate lyase

Biochemical and Biophysical Research Communications, 1969
Abstract β-Bromopyruvate (BrP) alkylates isocitrate lyase at the active site as indicated by the following: (1) the irreversible alkylation shows saturation kinetics, (2) substrate, isocitrate, is a competitive inhibitor of inactivation by BrP, (3) the combination of products, glyoxylate and succinate, or a competitive inhibitor of the enzyme ...
T E, Roche, B A, McFadden
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The occurrence and assay of isocitrate lyase in algae

Archives of Biochemistry and Biophysics, 1964
Abstract A modified method of isocitrate lyase assay is described which, coupled with the phenylhydrazone assay of keto acids, allows an accurate and definitive measurement of the enzyme activity. This eliminates the ambiguity associated with the use of only one assay of a nonspecific nature, such as the semicarbazone or phenylhydrazone methods. The
W G, HAIGH, H, BEEVERS
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Genetics and function of isocitrate lyase in Coprinus

Molecular and General Genetics MGG, 1977
Thirteen chromosomal loci have been identified which affect acetate metabolism in Coprinus. Mutants at only two loci, acu-l and acu-7, are deficient in isocitrate lyase (ICL) (EC 4.1.3.1) activity. acu-1 mutants are unable to induce ICL because they lack acetyl-CoA synthetase which is required to convert acetate to the metabolic inducer of ICL.
H B, King, L A, Casselton
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Hormonal control of isocitrate lyase synthesis

Biochimica et Biophysica Acta (BBA) - General Subjects, 1967
Abstract Isocitrate lyase ( L s-isocitrate glyoxylate-lyase, EC 4.1.3.1) was present in the cotyledons of dry seeds of peanut and squash. Activity of the enzyme increased markedly in squash cotyledons during the first 3 days of germination, and over half the increase was under the control of axial tissue.
D, Penner, F M, Ashton
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The role of isocitrate lyase in the metabolism of algae

Proceedings of the Royal Society of London. Series B. Biological Sciences, 1966
Abstract The incorporation of isotope from [2-14C]ethanol by cultures of the Brannon no. 1 strain of Chlorella vulgaris, growing on ethanol aerobically in the dark, was consistent with the operation of the tricarboxylic acid and glyoxylate cycles.
L C, Harrop, H L, Kornberg
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Isocitrate lyase: Artifacts and multiple enzyme forms

Archives of Biochemistry and Biophysics, 1983
Multiple enzyme forms of isocitrate lyase from various sources have been frequently reported. Protease action after cell rupture was sporadically claimed to explain the observed multiple enzyme forms. In this communication studies which are consistent with a protease action in vitro on isocitrate lyase of Pinus pinea germinating seeds are reported ...
PINZAUTI, GIANCARLO, GIACHETTI, EUGENIO, VANNI, PAOLO   +2 more
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ISOCITRATE LYASE IN AN ALGINOLYTIC BACTERIUM

Canadian Journal of Microbiology, 1963
Glyoxylate has been discerned as an apparent intermediate in mannuronate dissimilation by A. alginicum. Isocitrate lyase was demonstrated in extracts of the bacterium, even after prolonged culture on seawater nutrient broth. Resting cells were able to oxidize glyoxylate slowly, but none of the enzymes usually accounting for glyoxylate catabolism were ...
Joy Williams, R. L. Todd, W. J. Payne
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Coexistence of isocitrate lyase and NADP-isocitrate dehydrogenase in Turbatrix aceti mitochondria

Biochemical and Biophysical Research Communications, 1978
Abstract Glyoxylate and Krebs cycle marker enzymes cobanded on sucrose gradients after isopycnic centrifugation of mitochondrial pellets. Mitochondrial heterogeneity was investigated by treating particles with a Nitro Blue Tetrazolium reaction mixture designed to specifically increase the buoyant density of mitochondria containing the Krebs cycle ...
M P, McKinley, R N, Trelease
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Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase

Journal of Structural Biology, 2021
In Saccharomyces cerevisiae, the glyoxylate cycle is controlled through the posttranslational regulation of its component enzymes, such as isocitrate lyase (ICL), which catalyzes the first unique step of the cycle. The ICL of S.cerevisiae (ScIcl1) is tagged for proteasomal degradation through ubiquitination by a multisubunit ubiquitin ligase (the ...
Keito, Hiragi, Kazuya, Nishio, Shu, Moriyama, Tasuku, Hamaguchi, Akira, Mizoguchi, Koji, Yonekura, Kazutoshi, Tani, Tsunehiro, Mizushima   +7 more
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Apparent isocitrate lyase activity in Leishmania amazonensis

Acta Parasitologica, 2017
AbstractEarly reports have demonstrated the occurrence of glyoxylate cycle enzymes in ...
Concepción, Hernández-Chinea, Laura, Maimone, Yelitza, Campos, Walter, Mosca, Pedro J, Romero   +4 more
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