Results 211 to 220 of about 18,230 (249)
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Hormonal control of isocitrate lyase synthesis
Biochimica et Biophysica Acta (BBA) - General Subjects, 1967Abstract Isocitrate lyase ( L s-isocitrate glyoxylate-lyase, EC 4.1.3.1) was present in the cotyledons of dry seeds of peanut and squash. Activity of the enzyme increased markedly in squash cotyledons during the first 3 days of germination, and over half the increase was under the control of axial tissue.
Floyd M. Ashton, Donald Penner
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Coexistence of isocitrate lyase and NADP-isocitrate dehydrogenase in Turbatrix aceti mitochondria
Biochemical and Biophysical Research Communications, 1978Abstract Glyoxylate and Krebs cycle marker enzymes cobanded on sucrose gradients after isopycnic centrifugation of mitochondrial pellets. Mitochondrial heterogeneity was investigated by treating particles with a Nitro Blue Tetrazolium reaction mixture designed to specifically increase the buoyant density of mitochondria containing the Krebs cycle ...
Richard N. Trelease, Michael P. McKinley
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Isocitrate lyase: Artifacts and multiple enzyme forms
Archives of Biochemistry and Biophysics, 1983Multiple enzyme forms of isocitrate lyase from various sources have been frequently reported. Protease action after cell rupture was sporadically claimed to explain the observed multiple enzyme forms. In this communication studies which are consistent with a protease action in vitro on isocitrate lyase of Pinus pinea germinating seeds are reported ...
PINZAUTI, GIANCARLO +2 more
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Advances in Mycobacterial Isocitrate Lyase Targeting and Inhibitors
Current Medicinal Chemistry, 2012Isocitrate lyase plays a key role for survival of Mycobacterium tuberculosis in the latent form during a chronic stage of infection. This enzyme is important for M. tuberculosis during steady stage growth when it converts isocitrate to succinate and glyoxylate. Then, the glyoxylate is condensed with acetyl-CoA to form malate by malate synthase.
Martin Krátký, Jarmila Vinšová
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Stimulation of isocitrate lyase biosynthesis by hydroxylamine and hydrazine
Molecular and Cellular Biochemistry, 1977Recently it has been demonstrated that hydroxylamine is an activator of triglyceride catabolism. We have studied the effect of hydroxylamine on isocitrate lyase activity and lipid catabolism and have noted a stimulation of isocitrate lyase biosynthesis by 5 mM hydroxylamine.
VANNI, PAOLO +3 more
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Isolation and properties of watermelon isocitrate lyase
Phytochemistry, 1984Abstract The glyoxylate cycle enzyme, isocitrate lyase (EC 4.1.3.1) was purified from cotyledons of Citrullus vulgaris (watermelon). The final preparation, which had been 97-fold purified with a specific activity of 16.1 units/mg protein in a yield of 36%, was homogeneous by gel- and immunoelectrophoretic criteria.
Bruce A. McFadden +2 more
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Determination of isocitrate lyase activity in polyacrylamide gels
Analytical Biochemistry, 1972Abstract Isocitrate lyase (EC 4.1.3.1), the first enzyme of the glyoxylate cycle, catalyzes the aldol cleavage of threo- d s(+)-isocitric acid to succinic and glyoxylic acids. The enzyme plays a key role in the metabolism of short-chain fatty acids and has been found to be essential both in microbial growth on C2-compounds and in gluconeogenesis in ...
Henry C. Reeves, Marva J. Volk
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Targeting isocitrate lyase for the treatment of latent tuberculosis
Drug Discovery Today, 2017Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that can remain dormant for many years before becoming active. One way to control and eliminate TB is the identification and treatment of latent TB, preventing infected individuals from developing active TB and thus eliminating the subsequent spread of the disease ...
Ram Prasad Bhusal +4 more
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1969
Publisher Summary The anaplerotie function of isocitrate lyase and malate synthase during microbial growth on acetate is well documented. Catalysis by these enzymes is also vital in the conversion of lipid reserves to carbohydrates, as found, for example, early in the germination of fatty plant seedlings.
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Publisher Summary The anaplerotie function of isocitrate lyase and malate synthase during microbial growth on acetate is well documented. Catalysis by these enzymes is also vital in the conversion of lipid reserves to carbohydrates, as found, for example, early in the germination of fatty plant seedlings.
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Apparent isocitrate lyase activity in Leishmania amazonensis
Acta Parasitologica, 2017AbstractEarly reports have demonstrated the occurrence of glyoxylate cycle enzymes in ...
Laura Maimone +4 more
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