Results 61 to 70 of about 37,394 (195)

Iron‐Sulfur Cluster Targeting: A Novel Perspective for Treating Alcohol‐Related Lipid Metabolic Diseases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Alcohol metabolism induces structural instability of iron‐sulfur clusters through ROS‐mediated oxidative damage and direct covalent modification of acetaldehyde. The iron‐sulfur cluster deficiency drives metabolic reprogramming by inactivating aconitase, accumulating succinate, and impairing tRNA thiolation, thereby promoting hepatic steatosis ...
Li Xu, Zhenyang Xu, Chenli Su, Yanqian Zhao, Linjing Qiang, Xiayong Jing, Yuxiang Sun   +6 more
wiley   +1 more source

Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli

Molecular Systems Biology, 2014
Although protein acetylation is widely observed, it has been associated with few specific regulatory functions making it poorly understood. To interrogate its functionality, we analyzed the acetylome in Escherichia coli knockout mutants of cobB, the only
Sara Castaño‐Cerezo, Vicente Bernal, Harm Post, Tobias Fuhrer, Salvatore Cappadona, Nerea C Sánchez‐Díaz, Uwe Sauer, Albert JR Heck, AF Maarten Altelaar, Manuel Cánovas   +9 more
doaj   +1 more source

Bromopyrrole Alkaloids from the Sponge Agelas kosrae

Marine Drugs, 2018
Two new sceptrin derivatives (1,2) and eight structurally-related known bromopyrrole-bearing alkaloids were isolated from the tropical sponge Agelas kosrae.
Oh-Seok Kwon, Donghwa Kim, Heegyu Kim, Yeon-Ju Lee, Hyi-Seung Lee, Chung J. Sim, Dong-Chan Oh, Sang Kook Lee, Ki-Bong Oh, Jongheon Shin   +9 more
doaj   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Localization and targeting of isocitrate lyases in Saccharomyces cerevisiae [PDF]

Biochemical Journal, 1996
Native isocitrate lyase from castor bean and a C-terminally truncated variant were expressed in Saccharomyces cerevisiae under the control of a galactose-inducible promoter. Both forms of isocitrate lyase were targeted to the yeast peroxisomes. They co-fractionated with catalase on sucrose-density-gradient centrifugation of a post-nuclear supernatant ...
K M, Taylor, C P, Kaplan, X, Gao, A, Baker   +3 more
openaire   +2 more sources

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Investigating GERMs: how genotype, environment, and rhizosphere microbiome interactions underlie heat response in maize and sorghum

New Phytologist, Volume 251, Issue 4, Page 2152-2167, August 2026.
Three genotypes – a heat‐resistant maize (Zea mays), a heat‐susceptible maize, and a sorghum (Sorghum bicolor) variety – were grown to the V4 stage in growth chambers under optimal conditions or subjected to heat stress. Plants were grown in soil containing a complex microbial community, or in the same soil with a depleted microbiome.
Nate Korth, Isabella Borrero, Katelyn Rumley, Alex L. Woodley, Mallory J. Choudoir, Joseph L. Gage   +5 more
wiley   +1 more source

The Control of the Synthesis of Isocitrate Lyase in a Thermophilic Bacillus [PDF]

Journal of General Microbiology, 1979
From a strain of Bacillus stearothermophilus, devoid of active pyruvate carboxylase, a mutant (NG-15) was selected that grew on acetate in the presence of glucose. This mutant differed from its parent organism in possessing high activities of isocitrate lyase when grown on all carbon sources tested except nutrient broth, in possessing unusually low ...
openaire   +2 more sources

Elektroenzymatische CO2‐Fixierung

Angewandte Chemie, Volume 138, Issue 28, 6 July 2026.
Die elektroenzymatische CO2‐Fixierung ermöglicht eine energieeffiziente, hochselektive Synthese komplexer Moleküle. Um ihr volles Potenzial auszuschöpfen, ist ein grundlegendes Verständnis von elektrodengekoppelten Reduktasen und Carboxylasen erforderlich.
Leonardo Castañeda‐Losada, Michael Richter, Christophe Léger, Vincent Fourmond, Nicolas Plumeré   +4 more
wiley   +1 more source

Purification and regulatory properties of isocitrate lyase from Escherichia coli ML308

, 1988
Isocitrate lyase was purified to homogeneity from Escherichia coli ML308. Its subunit Mr and native Mr were 44,670 +/- 460 and 17,000-180,000 respectively.
Nimmo, H. G., MacKintosh, C.; id_orcid, Nimmo, H.G., MacKintosh, C.   +3 more
core   +1 more source