Results 101 to 110 of about 20,442 (252)
Cyclic butylene terephthalate (CBT®) is an interesting matrix material for the preparation of nanocomposites due to its very low, water-like melt viscosity which favours clay exfoliation. Nevertheless, polymerized CBT (pCBT) is inherently brittle.
T. Abt, J. J. Bou, M. Sanchez-Soto
doaj +1 more source
Ueber das Verhalten aromatischer Aldoxime gegen Isocyanate [PDF]
Heinrich Goldschmidt+1 more
openalex +1 more source
A Sydnonimine‐based Click‐and‐Release Approach to Cyclic Products
Macrocyclick‐and‐release: The combination of a chemoselective Cu‐catalyzed click‐and‐release reaction and pyrene tags allows efficient synthesis of macrocycles and easy isolation by simple filtration through graphitic material. Abstract Herein, we report a general, efficient, and practical methodology for the macrocyclization of compounds based on the ...
Guillaume Force+5 more
wiley +1 more source
PECULIARITIES OF ISOCYANATES INTERACTION WITH HYDRAZINE DERIVATIVES
The results of studies on chemical transformations of organic and organosilicon isocyanates in their interaction with hydrazine derivatives have been summarized in this review.
A. D. Kirilin+4 more
doaj +1 more source
Strategy‐Level Prodrug Synthesis
Organic synthesis uniquely provides opportunities to access molecules that serve defined purposes. Medicinal chemistry illustrates this attribute well with prodrug design, whereby a drug undergoes a late‐stage conversion to a conditionally responsive active medicinal agent (AMA), being a notable example.
Paul Geaneotes, Paul Floreancig
wiley +1 more source
This review summarizes the advances in the nanocellulose‐assisted preparation of composite films and aerogels for electromagnetic interference shielding application, highlights the significance of the microstructure design in performance enhancement, and points out the current challenges and outlook for these fascinating nanocellulose‐based composites.
Zhihui Zeng+4 more
wiley +1 more source
β‐Lactam Ylidenes: An Overlooked Class of N‐Heterocyclic Carbenes
A highly modular synthetic approach toward four‐membered β‐lactam carbenes (BLCs) is presented. BLCs feature moderate σ‐donor and strong π‐acceptor character, leading to a pronounced ambiphilic reactivity which includes the formation of olefinic dimers as well as unprecedented N2‐bridged dimers, oxirane formation with acetone, and fragmentation to ...
Leonard Karl+3 more
wiley +1 more source
This article describes the development of improved NEU1 inhibitors based on the 2‐deoxy‐2,3‐didehydro‐N‐acetyl neuraminic acid scaffold. A series of candidate inhibitors are designed containing bioisosteres of the C5‐amide group and evaluated for activity against NEU1‐4 enzymes.
Mostafa Radwan+2 more
wiley +1 more source
ROR1 kinase is an underexplored promising target for the development of novel anticancer drugs, being strongly expressed in several cancer cell lines, but poorly in non‐tumor cells. This property, together with the scarce number of molecules effective against ROR1, led us to design and develop a research program aimed to the discovery of new chemical ...
Gerardina Smaldone+17 more
wiley +1 more source