Results 161 to 170 of about 57,276 (400)
Strategy‐Level Prodrug Synthesis
Organic synthesis uniquely provides opportunities to access molecules that serve defined purposes. Medicinal chemistry illustrates this attribute well with prodrug design, whereby a drug undergoes a late‐stage conversion to a conditionally responsive active medicinal agent (AMA), being a notable example.
Paul Geaneotes, Paul Floreancig
wiley +1 more source
This review summarizes the advances in the nanocellulose‐assisted preparation of composite films and aerogels for electromagnetic interference shielding application, highlights the significance of the microstructure design in performance enhancement, and points out the current challenges and outlook for these fascinating nanocellulose‐based composites.
Zhihui Zeng+4 more
wiley +1 more source
Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
A good range of 1,4-dihydropyridines bearing a carbamate moiety on the 4-position were synthesized from the primary reaction of different hydroxyaldehydes with phenyl isocyanates and the subsequent reaction of the obtained carbamates with methyl ...
Davood Habibi+2 more
doaj +1 more source
Development of thermally stable phosphonitrile elastomers for advanced aerospace structures [PDF]
Both high and low molecular weight, curable poly(fluoroalkoxy phosphazene) terpolymers were prepared. These terpolymers resulted from reaction of (Cl2PNn) polymer with alkoxides derived from CF3CH2OH and C3F7CH2OH, and an alkoxide derived from CH3CH(OH ...
Gerber, A. H.+3 more
core +1 more source
β‐Lactam Ylidenes: An Overlooked Class of N‐Heterocyclic Carbenes
A highly modular synthetic approach toward four‐membered β‐lactam carbenes (BLCs) is presented. BLCs feature moderate σ‐donor and strong π‐acceptor character, leading to a pronounced ambiphilic reactivity which includes the formation of olefinic dimers as well as unprecedented N2‐bridged dimers, oxirane formation with acetone, and fragmentation to ...
Leonard Karl+3 more
wiley +1 more source
A series of new derivatives was prepared by derivatisation of the 7-amino moiety present in 7-amino-3,4-dihydroquinolin-2(1H)-one, a compound investigated earlier as CAI.
Murat Bozdag+4 more
doaj +1 more source
Determination of phenylurethane and isocyanate groups in isocyanates
Reactions of phenylurethane and isocyanate groups of arylisocyanates with secondary amines are studied by IR spectrometry and potentiometric titration. It is found that the rate of the reaction between isocyanate groups and diethylamine is nearly independent of the solvent nature.
Evtushenko Yu.M.+2 more
openaire +1 more source
Medical screening of workers is one of the tools often used to assess suitability for work and to attempt to reduce worker ill-health. This article outlines the objectives of the screening process and the basic criteria to be followed in developing a ...
Gauci, Mark, Vella, Noel
core
This article describes the development of improved NEU1 inhibitors based on the 2‐deoxy‐2,3‐didehydro‐N‐acetyl neuraminic acid scaffold. A series of candidate inhibitors are designed containing bioisosteres of the C5‐amide group and evaluated for activity against NEU1‐4 enzymes.
Mostafa Radwan+2 more
wiley +1 more source