Insertion of CO<sub>2</sub>, Isocyanates, and Acetonitrile into the P-Si Bond of a Silyl-Substituted <i>N</i>‑Heterocyclic Carbene Phosphinidene. [PDF]
Hochholzer A +3 more
europepmc +1 more source
Flavonoid Oxime Carbamate Derivatives: Reversal of Multidrug Resistance in Cancer Cells
A set of 23 new flavonoid oxime carbamates was synthesized and evaluated as multidrug resistance (MDR) reversers in ABCB1‐transfected mouse lymphoma cells. All derivatives strongly inhibited P‐glycoprotein (P‐gp) efflux activity in a transport assay, while most selected compounds behaved as ATPase inhibitors. In drug combination assays, they interacted
Filipa Barbosa +5 more
wiley +1 more source
Targeted covalent inhibitors (TCI) containing cyclic imine warheads react with tyrosine and tryptophan residues via the Mannich reaction. These cyclic imine warheads show comparable reaction kinetics to cysteine‐reactive electrophiles commonly used in TCIs.
Sijie Wang +6 more
wiley +2 more sources
Substituting Fossil-Based into Bio-Based Isocyanates for Resin and Dispersion Polyurethane Coatings: Evaluation of Thermal, Mechanical, and Chemical Performance. [PDF]
Samyn P, Cosemans P.
europepmc +1 more source
The development of effective strategies for the detoxification of organophosphorus (OP) nerve agents has evolved from the early mechanistic studies of François Terrier and collaborators, who first elucidated the exceptional nucleophilicity of α‐effect species such as oximes and hydroxamates, to the modern design of supramolecular and material‐based ...
Pedro Rodríguez‐Dafonte
wiley +1 more source
Minimal N-hydroxyphthalimide-urethane bonds enable superior thermomechanical stability for covalent adaptable networks. [PDF]
Yin Y +13 more
europepmc +1 more source
Getting Started in Synthesis: A Tabular Guide to Selected Monofunctional Fluorous Compounds [PDF]
Rábai, József
core +1 more source
Back to the Electrofuture: Named Reactions Powered by Electroorganic Syntheses
Bridging classical named reactions with modern electroorganic chemistry, this review presents how electrochemical strategies can revive and reinterpret historically significant transformations, highlighting their emerging potential as sustainable alternatives in contemporary organic synthesis.
Debajit Maiti +4 more
wiley +1 more source
Effect of covalent functionalisation with isocyanates on the electrochemical properties of exfoliated black phosphorus electrodes. [PDF]
Jakóbczyk P +5 more
europepmc +1 more source
To Bend or Not to Bend: Revealing the Stereoelectronic Origin of the Distorted <i>sp</i> Carbon in Isocyanates. [PDF]
Araujo L +3 more
europepmc +1 more source

