Results 11 to 20 of about 39,402 (215)

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi-Target Inhibitors of Cholinesterases and Carbonic Anhydrases. [PDF]

open access: yesJ Biochem Mol Toxicol
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Ünlü S   +3 more
europepmc   +2 more sources

Current status and future perspectives of platelet function-guided precision antiplatelet therapy for patients with cerebral infarction. [PDF]

open access: yesNeuroprotection
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Zhu G   +7 more
europepmc   +2 more sources

Seleção de genótipos de aceroleira assistida por marcadores isoenzimáticos visando à resistência a Meloidogyne incognita raça 2 Genotype selection of Barbados cherry using iso-enzymatic markers for resistance to Meloidogyne incognita race 2

open access: yesRevista Brasileira de Fruticultura, 2008
A cultura da aceroleira despertou um grande interesse do mercado consumidor, tendo em vista o alto teor de vitamina C (ácido ascórbico), que varia entre 1.325 a 2.250 mg por 100 mL de suco.
Jackeline Gadé de Araujo Rossiter   +4 more
doaj   +1 more source

Aspartate aminotransferase isoenzymes in cucumber roots as depending upon the mineral composition of the medium

open access: yesActa Societatis Botanicorum Poloniae, 2014
Aspartate aminotransferase (GOT) isoenzymes separated by means of electrophoresis on cellulose acetate gel were examined. Five GOT isoenzymes were discovered in cucumber roots after several days of their growth.
Genowefa Kubik-Dobosz
doaj   +1 more source

Kinetic and thermodynamic Studies Of Alanine Aminopeptidase(AAP) Isoenzymes I,II Partially Purified From Patient's Urine With Urinary Tract Cancer

open access: yesمجلة بغداد للعلوم, 2014
The activity of Alanine aminopeptidase( AAP ) was measured in the urine of healthy and urinary tract cancer patients , the results showed higher activity of (AAP) in patients compared to healthy .
Baghdad Science Journal
doaj   +1 more source

Kinetic studies of AST isoenzymes I,II,III,IV partially purified from patient,s urine with chroinc renal failure

open access: yesمجلة بغداد للعلوم, 2010
In this research, the kinetic studies of four isoenzymes of Asprtate aminotransferase, which partially purified from the urine of chronic renal failure patients were carried out .The four isoenzymes were obeyed Michaelis-Menton's equation and the ...
Baghdad Science Journal
doaj   +1 more source

Superoxide dismutase activity as a function of culture aging of B-16 mouse melanoma cells [PDF]

open access: yesJournal of the Serbian Chemical Society, 2004
The C3 clone of B-16 mouse melanoma was cultured for 1, 6 and 9 days and analysed. The changes which are not directly linked to melanogenesis in the B-16 / C3 cultures during their maturation were characterized. Early (1 day), confluent (6 days) and old (
JOVANA B. SIMIC-KRSTIC   +4 more
doaj  

Urinary N-acetyl-beta -D-glucosaminidase and its isoenzymes A & B in workers exposed to cadmium at cadmium plating

open access: yesJournal of Occupational Medicine and Toxicology, 2007
Objective The present study was carried out to determine the effect of cadmium exposure on Urinary N-acetyl-beta -D-glucosaminidase and its isoenzymes A and B in workers exposed at cadmium plating. Methods 50 subjects using cadmium during cadmium plating
Rajan BK   +3 more
doaj   +1 more source

Extraction, purification and characterization of invertase from Candida guilliermondii isolated from peach solid wastes

open access: yesRevista Brasileira de Fruticultura, 2022
The best conditions for in vitro sucrose hydrolysis based on invertase from Candida guilliermondii (ICg) were studied and the kinetic parameters KM,Vmax, and thermal stability of ICg were determined.
Tariani Lemos Avila   +5 more
doaj   +1 more source

The Hydrolysis Rate of Paraoxonase-1 Q and R Isoenzymes: An In Silico Study Based on In Vitro Data

open access: yesMolecules, 2022
Human serum paraoxonase-1 (PON1) is an important hydrolase-type enzyme found in numerous tissues. Notably, it can exist in two isozyme-forms, Q and R, that exhibit different activities. This study presents an in silico (QSAR, Docking, MD and QM/MM) study
Sedat Karabulut   +4 more
doaj   +1 more source

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