Results 31 to 40 of about 50,359 (250)

Frequency distributions of (Spearman’s rank) correlations for fast- and slow-evolving isoenzymes.

open access: yes, 2017
Each isoenzyme in an isoenzyme gene set was categorized as one of: fast-evolving (highest evolutionary rate within the isozyme set), slow-evolving (lowest rate), or neutral.
Christopher Jacobs (3687193)   +3 more
core   +1 more source

Unmasking Glycoforms: Lectin‐Based Profiling and Functional Implications of Targeted Glycosylation Knockouts in Chinese Hamster Ovary Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Monoclonal antibody (mAb) glycosylation is a critical quality attribute that is difficult to rationally engineer and rapidly assess during cell line development. Here, we investigate whether cell‐surface glycosylation can serve as a surrogate readout of mAb product glycosylation following targeted glycogene engineering in CHO cells.
Cristina Abascal Ruiz   +6 more
wiley   +1 more source

Higher genetic variation estimated by microsatellites compared to isoenzyme markers in Aedes aegypti from Rio de Janeiro

open access: yesMemorias do Instituto Oswaldo Cruz, 2006
Aedes aegypti populations from five districts in Rio de Janeiro were analyzed using five microsatellites and six isoenzyme markers, to assess the amount of variation and patterns of gene flow at local levels.
Magda Clara Vieira da Costa-Ribeiro   +2 more
doaj   +1 more source

CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]

open access: yes, 2004
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L.   +9 more
core   +1 more source

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul   +5 more
wiley   +1 more source

Some important aspects in Moringa oleifera Lam. micropropagation

open access: yesActa Agriculturae Slovenica, 2019
Type and source of explant as well as the type of cytokinin were important factors for successful moringa micropropagation. Explants obtained from in vitro grown plant materials were better than others obtained from soil growing seedlings.
Abdullah EL-NAGISH   +3 more
doaj   +1 more source

Genetic developmental and epileptic encephalopathies in adulthood: Gaps in evidence and care

open access: yesEpilepsia Open, EarlyView.
Abstract Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of the most severe epilepsies, characterized by seizure onset and neurodevelopmental delay in infancy or childhood, often with additional neurological and systemic comorbidities.
Alex M. Dudley   +5 more
wiley   +1 more source

The isoenzymes of isocitrate dehydrogenase in Acinetobacter lwoffi.

open access: yes, 1969
Preliminary results had indicated that the isocitric dehydrogenase (IDH) of the bacterium Acinetobacter lwoffi 4B was activated by low levels of glyoxylate. Furthermore, in the presence of glyoxylate the enzyme had been found to be more stable to heat or
Colin Henry. Self (7633358)
core   +3 more sources

STUDIES OF ACID PHOSPHATASE ISOENZYMES IN HUMAN LEUKOCYTES

open access: yes, 1970
Seven acid phosphatase isoenzymes, namely 0, 1, 2, 3, 3b, 4 and 5, in human leukocytes have been separated both by acrylamide gel electrophoresis and by ion exchange chromatography.
L. T. YAM, C. Y. LI, K. W. LAM
core   +1 more source

Analgesic use, safety and pharmacokinetics of acetaminophen in equids: A structured scoping review

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Despite its frequent use in equine clinical practice, scientific data on the use of acetaminophen in horses remain limited. Objective To map and critically appraise the available evidence on the analgesic use, safety and pharmacokinetics of acetaminophen in horses. Study Design Structured scoping review.
Francisco Medina‐Bautista   +2 more
wiley   +1 more source

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