Results 51 to 60 of about 45,019 (252)
Memorias do Instituto Oswaldo Cruz, 1993 Four cytotypes of Simulium exiguum occur in Ecuador, where this morphospecies is the primary vector of onchocerciasis. In this paper, we give the first full description of the banding pattern of the larval polytene chromosomes of the Quevedo cytotypes ...
M. Charalambous +4 more
doaj +1 more source
Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
Differential susceptibility of human alcohol dehy drogenase isoenzymes to anions
, 1984 Human liver alcohol dehydrogenase (ADH) isoenzymes β1β1, γ1γ1 from Caucasian individuals with ‘typical’ ADH and β2β2-Bern from Caucasian individuals with ‘atypical’ phenotype differed in their susceptibility to anions.
Bühler, R. +3 more
core +1 more source
Isoenzymes in Clinical Diagnosis [PDF]
Circulation, 1965 The recent literature attests to the increasing number of enzymes for which isoenzymes or subunit structure or both are known. Several symposia and reviews have been published within the past few years. 46-50 Some enzyme activities for which isoenzymes have been described are listed in table 4.
T L, Goodfriend, N O, Kaplan
openaire +2 more sources
Shikimate pathway disruption in yeast induces metabolite self‐assembly into toxic aggregates
The FEBS Journal, EarlyView.In Saccharomyces cerevisiae, shikimate pathway disruption induces toxic metabolite assemblies. Deleting ARO4 plus phenylalanine (Phe) feeding causes Phenylalanine accumulation, lowers ARO3 activity, and triggers amyloid‐like fibril formation. Deleting ARO3 plus tyrosine (Tyr) feeding leads to Tyrosine buildup and similar fibril assembly.
Hanaa Adsi +6 more
wiley +1 more source
The FEBS Journal, EarlyView.The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati +4 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Botrytis cinerea is a widespread plant pathogenic ascomycete that causes grey mould in over 1400 species and impacts global crop yields. Double‐stranded RNA (dsRNA)‐induced gene silencing is a promising technology for pest control, but efficient delivery remains a major challenge.
Mei Guan +7 more
wiley +1 more source
Scientia Agricola, 1994 No presente trabalho foram determinados o perfil isoenzimático diferencial de esterase e peroxidase, a proteína total solúvel e os sólidos solúveis (sacarose) em graus brix, de 10 cultivares de cana-de-açúcar (Saccharum spp.) atualmente cultivados no ...
M. de Almeida, O. J. Crócomo
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu +4 more
wiley +1 more source
, 2009 An investigation was conducted on the chitinase isoenzymes in various tissues of 1-week-old sorghum seedlings that had been inoculated with the fungal pathogens Fusarium thapsinum and Fusarium proliferatum.
Huang, Liandong, Backhouse, David
core +1 more source