Latar Belakang dan Tujuan: Pasien dengan tumor otak sering mengalami gangguan fungsi kognitif yang berdampak terhadap fungsi fisik, psikologis, sosial, dan vokasional.
Caroline Wullur +2 more
doaj +2 more sources
The inhibitory SAPS3-AMPK interaction detected in HEK293 cells is not detectable in muscle or liver from humans or mice. [PDF]
This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Birk JB +3 more
europepmc +2 more sources
Case Report of Ultrasonographic and Computed Tomography Findings of Presumed Traumatic Ocular Globe and Lens Rupture in a Cat. [PDF]
A 5‐year‐old female spayed domestic short hair cat was presented 2 weeks after a history of unknown trauma. The examination of the head revealed facial asymmetry. Vision tests, including menace responses, were negative. Pupillary light reflexes and dazzle reflexes were negative in both eyes.
Klever J, Koch C, Fischer MC.
europepmc +2 more sources
Prevalence and degree of orotracheal intubation-related tracheal lesions in horses. [PDF]
Abstract Background Orotracheal intubation is commonly performed for inhalation anaesthesia in horses to ensure safe and reliable administration of volatile anaesthetics and to secure the airways. In human and equine medicine, the occurrence of intubation‐associated complications has been described, which can range from mild mucosal irritation to ...
Parente A +4 more
europepmc +2 more sources
Trigeminal Nerve Asymmetry in Horses With Idiopathic Trigeminal-Mediated Headshaking: A Retrospective Case-Control Magnetic Resonance Imaging Study. [PDF]
ABSTRACT Background Nerve atrophy results in trigeminal nerve (TN) asymmetry detectable by magnetic resonance imaging (MRI) in humans, but similar studies have not been performed in horses with idiopathic trigeminal‐mediated headshaking (ITMHS). Hypothesis Horses with ITMHS show greater MRI‐detected trigeminal‐nerve asymmetry than controls.
Heun F +3 more
europepmc +2 more sources
Two Coupled Continuous-Flow Ventricular Assist Devices as a Novel BIVAD With One Driveline: Acute Animal Study Results. [PDF]
The DuoCor BiVAS, a novel biventricular assist system, demonstrated successful implantation and stable hemodynamic support in an acute large animal model. The study highlights the system's potential for treating severe heart failure, with promising implications for patient mobilization and quality of life, warranting further clinical investigation ...
Knigge S +13 more
europepmc +2 more sources
Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery. [PDF]
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Samaridou E +4 more
europepmc +2 more sources
An Evaluation of Genotoxicity and 90-Day Repeated-Dose Oral Toxicity in Rats of DracoBelle Nu sd. [PDF]
A powdered water extract of D. moldavica, DracoBelle Nu sd, did not induce gene mutations in a bacterial reverse mutation assay, did not induce genotoxicity in an mammalian micronucleus test (MMT), and did not cause adverse effects in male or female Han:WIST rats after 90/91 consecutive days of oral gavage administration of 250, 500, and 1000 mg/kg bw ...
Choi B +7 more
europepmc +2 more sources
Wild‐type mice inoculated with B16BL6 or B16‐NC cells developed large tumors and exhibited autophagy, neuroinflammation, and pain hypersensitivity. In contrast, the ablation of Snca, either globally (Snca−/− mice inoculated with B16BL6 cells) or locally (wild‐type mice inoculated with B16‐Snca−/− cells), reduced tumor growth and tumor‐induced ...
Ellen Niederberger +7 more
wiley +1 more source
Laparoskopi Hemihepatektomi pada Hepatoseluler Karsinoma Hemiliver Dextra Et Causa Hepatitis B
Latar Belakang: Reseksi hati untuk karsinoma hepatoseluler (HCC) saat ini dikenal sebagai prosedur yang lebih aman daripada sebelumnya karena kemajuan teknis dan perbaikan dalam manajemen pasien pascaoperasi dan tetap menjadi pengobatan lini pertama ...
Ika Jati Setya Andriani +1 more
doaj +1 more source

