Results 201 to 210 of about 228,231 (339)

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source

Isoflurane preconditioning induced genomic changes in mouse cortex

BJA Open
Background: Altered patterns of genetic expression induced by isoflurane preconditioning in mouse brain have not yet been investigated. The aim of our pilot study is to examine the temporal sequence of changes in the transcriptome of mouse brain cortex ...
Umeshkumar Athiraman, Tusar Giri
doaj  

Effect of Tapentadol on Dogs' Minimum Alveolar Concentration (MAC) of Isoflurane. [PDF]

Animals (Basel)
Ibancovichi-Camarillo JA, Chávez-Monteagudo JR, De Paz-Campos MA, Gutiérrez-Olvera L, Sumano-López HS.   +4 more
europepmc   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

Impact of Mechanical Ventilation and Anesthesia on PET Tracer Kinetics for Combined PET/fMRI Studies in Rats. [PDF]

Mol Imaging Biol
Ma Y, Kuebler L, Haas S, Maurer A, Herfert K.   +4 more
europepmc   +1 more source

LAPAROSCOPY: BLOOD-GAS VALUES AND MINOR SEQUELAE ASSOCIATED WITH THREE TECHNIQUES BASED ON ISOFLURANE

, 1987
J.P. KENEFICK, Arthur Leader, J. R. Maltby, Patrick J. Taylor   +3 more
openalex   +1 more source

Regional Blood Flow and Tissue Oxygen Pressures of the Collateral-Dependent Myocardium during Isoflurane Anesthesia in Dogs [PDF]

, 1989
P. Conzen, Jonny Hobbhehn, Alwin E. Goetz, P. Gonschior, Gabriele Seldi, Klaus Peter, W. Brendel   +6 more
openalex   +1 more source

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

Advanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang, Bo Cheng, Chenyue Zhang, Chenglong Zhao, Ruiqing Wang, Xun Zhang, Dizhi Jiang, Xinyu Zhang, Xinyue Ma, Hongyuan Mao, Zerun Li, Chenhan Huang, Tianzi Wang, Kaiyue Guo, Liwen Wang, Ning Tang, Haiyong Wang   +16 more
wiley   +1 more source

Baseline CBV-normalized BOLD fMRI of visual stimulation in awake vs. anesthetized mice. [PDF]

J Cereb Blood Flow Metab
Choi SH, Im GH, Le TT, Lee CH, Kim SG.
europepmc   +1 more source

SINGLE BREATH INDUCTION OF ANAESTHESIA WITH ISOFLURANE

, 1987
John Lamberty, Iain H. Wilson
openalex   +1 more source