Results 21 to 30 of about 1,646 (102)

Familial isolated congenital asplenia: case report and literature review

European Journal of Pediatrics, 2009
Congenital asplenia is a rare life-threatening condition, often presenting with pneumococcal sepsis. It may arise as part of situs abnormalities or result from an unrelated specific defect of spleen development. The mode of inheritance is usually autosomal dominant, though sporadic cases are also reported.
Ahmed, SA, Zengeya, S, Kini, U, Pollard, A   +3 more
openaire   +2 more sources

Childhood Morgagni hernia: report of two cases

Journal of Pediatric and Neonatal Individualized Medicine, 2017
Morgagni diaphragmatic hernia is a rare congenital anomaly to be seen in the pediatric age group. We are reporting two cases of Morgagni hernia, which presented with non-specific symptoms and posed a diagnostic dilemma.
Kamal Nain Rattan, Jasbir Singh, Poonam Dalal   +2 more
doaj   +1 more source

TRANSPOSITION OF GREAT ARTERIES: NEW INSIGHTS INTO THE PATHOGENESIS

Frontiers in Pediatrics, 2013
Transposition of great arteries (TGA) is one of the most common and severe congenital heart diseases (CHD). It is also one of the most mysterious CHD because it has no precedent in phylogenetic and ontogenetic development, it does not represent an ...
Marta eUnolt, Carolina ePutotto, Lucia Martina Silvestri, Dario eMarino, Alessia eScarabotti, Valerio eMassaccesi, Angela eCaiaro, Paolo eVersacci, Bruno eMarino, Bruno eMarino   +9 more
doaj   +1 more source

Bleeding Disorders in Children With Genetic Diseases: A Narrative Review. [PDF]

Acta Paediatr
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Cagol R, Sbeity Barakat M, Willems M, Akbaraly T, Christine BA, Diaz I, Theron A.   +6 more
europepmc   +2 more sources

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Laparoscopic Splenectomy for a Completely Infarcted Wandering Spleen After Prolonged Positional Abdominal Pain: A Case Report and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 19‐year‐old woman had a 7–8‐year history of positional abdominal pain, a mobile mass and transient thrombocytopenia. Computed tomography showed a completely infarcted wandering spleen with pedicle torsion. Fully laparoscopic splenectomy succeeded despite total infarction.
Toufic Awwad, Ahmad Jradi, Riwa Deghaim, Mohamad Khalife   +3 more
wiley   +1 more source

Asplenia in a patient with Fanconi's anemia-like congenital aplastic anemia

The Turkish Journal of Pediatrics, 2000
Fanconi's anemia (FA) is an autosomal recessive disease manifested by pancytopenia resulting from bone marrow failure, variable physical anomalies and cancer susceptibility.
E Erduran, A Okten, G Kaya, A Yildiran
doaj  

EHA Guidelines on the management of children and adults with hemoglobin SC disease

HemaSphere, Volume 10, Issue 10, October 2026.
Abstract HbSC disease is the second most common type of sickle cell disease (SCD) in populations of African origin. Although it is often grouped together with other types of SCD, particularly sickle cell anemia (HbSS), it has unique pathophysiology and a different spectrum of laboratory and clinical features.
David C. Rees, Valentine Brousse, Mariane de Montalembert, Bart J. Biemond, Lucia De Franceschi, Eugene Oteng‐Ntim, Pagona Flevari, Valeria Pinto, John James, Elena Cela, Stefan Eber, Rachel Kesse‐Adu, Jennifer Knight‐Madden, France Pirenne, Aline Santin, Andreas Glenthøj   +15 more
wiley   +1 more source

Influenza Vaccination Effectiveness in Preventing Hospitalization of Adults With Underlying Medical Conditions: A Multicentre Case–Control Study

Influenza and Other Respiratory Viruses, Volume 20, Issue 9, September 2026.
ABSTRACT Background Seasonal influenza, especially in persons with underlying medical conditions, is a substantial global burden. Influenza vaccination effectiveness (VE) varies annually, requiring continuous evaluation due to evolving viruses and vaccination coverages. Our aim was to investigate influenza VE in preventing hospitalization for confirmed
Diana Toledo, Núria Soldevila, Juan Carlos Galan, Pere Godoy, María Morales‐Suarez‐Varela, Marta Rodriguez‐Suárez, María Grau, Tania Fernández‐Villa, Aurea Morillo, Gemma Navarro, Judith Chamorro, Angela Domínguez, Project PI19/00354 Working Group, Raquel Valencia, María Amelia Fernández‐Sierra, María Mar Rodríguez, José Antonio Marín, Gerardo Rubiera, Vicente Martín, Graciela López‐Muñiz, Carmen Fernández Martínez de Septien, Silvia Fernández, Núria Torner, Carles Vilaplana, Lluís Forcadell, Cristina Rius, Anna Vilella, Silvia Simó‐Nebot, Eva del Amo, Magda Campins, Xavier Martínez, José Angel Rodrigo, Judith Martínez, Ramon Boixeda, Julia Jaumandreu, Jenaro Astray, Concepción Prados‐Sánchez, Alberto Mangas‐Moro, Amaranta McGee‐Laso, Laura Moreno‐Galarraga, Nerea Díaz‐Sánchez, Idaira Fernandez‐Rodriguez, Cristina Llonch, Itziar Casado, Fernando Baigorria‐Feltrin, Alba Gasque, Sara Marquínez‐Noriega, Mikel Egurrola‐Izquierdo, Patricia García, Isabel Peraita‐Costa, Francisco Sanz   +50 more
wiley   +1 more source