Results 81 to 90 of about 1,922,635 (306)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Current-Fed Isolated DC/DC Converter for Future Aerospace Microgrids [PDF]

, 2019
High-performance power conversion equipment is currently gaining an increasing interest for aircraft applications. In particular, isolated bidirectional dc/dc converters are often proposed for modern aircraft distribution systems.
Tarisciotti, Luca, Galea, Michael, Chen, Linglin, Walker, Adam, Costabeber, Alessandro   +4 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Isolated, multiple-output voltage dc-to-dc converter [PDF]

, 1969
Isolated, multiple output voltage dc-to-dc converter provides power for television transmitter used in space vehicles. The isolation is accomplished by using a single-end switching transformer circuit.

core  

Comparison between two VSC-HVDC transmission systems technologies : modular and neutral point clamped multilevel converter [PDF]

, 2009
The paper presents a detail comparison between two voltage source converter high voltage dc transmission systems, the first is based on neutral point-clamped (also known as HVDC-Light) and the second is based on innovative modular multilevel converter ...
Anaya-Lara, O., Finney, S.J., Burt, G.M., Adam, G.P., Williams, B.W., McDonald, J.R.   +5 more
core   +2 more sources

An Extensive Overview and Analysis of Recent Advancements in Multiport Converter Topologies and Control Techniques

IEEE Access
The evolution of renewable energy-based power systems and smart grids has posed challenges in the development of innovative power conversion systems. The fluctuating load demands coupled with the intermittent nature of RES necessitate the combination of ...
Laishram Nikita Chanu, Balaji Subramanian   +1 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Study of non-isolated CD – DC CUK converter with multiple outputs

, 2015
The 6th International Engineering Invention & Innovation Exhibition 2015 (i-ENVEX 2015) was organized by ENVEX Young Researcher Club (EYReC), University Malaysia Perlis (UniMAP) and Ministry of Higher Education (MOHE), Malaysia on 17th - 19th April 2015,
Lian, Chai Wei
core  

Analysis, Design, and Hardware Implementation of Phase Shifted Isolated DC–DC Converter for Low Voltage Electric Vehicle Battery Charging Applications

IEEE Access
Electric vehicles are gaining importance due to their clean and environmentally friendly nature, contributing to the reduction of pollution and global warming caused by the fossil fuels.
Pulipaka Srikanth, G. Arunkumar
doaj   +1 more source