Results 121 to 130 of about 53,308 (359)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Review, Properties, and Synthesis of Single-Switch Non-Isolated DC-DC Converters with a Wide Conversion Range

open access: yesSensors
The cascaded connection of power converters extends conversion ranges but requires careful consideration due to high component count and efficiency concerns, as power is processed redundantly.
Fernando Lessa Tofoli   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Multi-Port Non-Isolated DC-DC Converters and Their Control Techniques for the Applications of Renewable Energy

open access: yesIEEE Access
In recent times, the increasing demand for energy consumption on a global scale and the prevalent use of power electronics DC-DC converters in various applications, such as hybrid energy systems, hybrid vehicles, aerospace, satellites, and portable ...
R. Aravind   +4 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Waveform-level time-domain simulation comparison study of three shipboard power system architectures [PDF]

open access: yes, 2012
Detailed waveform-level modeling and simulation of three alternative shipboard power system architectures is presented herein. The three system architectures are based on conventional 60Hz medium-voltage ac (MVAC), higherfrequency 240Hz medium-voltage ac
Crider, J.   +9 more
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Overview of Bidirectional DC DC Converter for Energy Storage System in Renewable Energy Power Generation

open access: yesProtek: Jurnal Ilmiah Teknik Elektro
The integration of renewable energy sources (RES), such as wind and solar energy, has become increasingly growth in power generation systems. However, the intermittent and variable nature of these sources poses challenges, especially in maintaining the ...
Tyas Kartika Sari   +3 more
doaj   +1 more source

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