Results 101 to 110 of about 87,203 (297)

Hypertension [PDF]

, 2004
Hypertension is a rapidly moving clinical field with frequent developments in new pharmacologic agents and management strategies. Perhaps more importantly, there have been substantial improvements in our understanding of how best to use the drugs ...
Farrugia, Emanuel
core  

Decreased soluble guanylate cyclase contributes to cardiac dysfunction induced by chronic doxorubicin treatment in mice [PDF]

, 2017
Aims: The use of doxorubicin, a potent chemotherapeutic agent, is limited by cardiotoxicity. We tested the hypothesis that decreased soluble guanylate cyclase (sGC) enzyme activity contributes to the development of doxorubicin-induced cardiotoxicity ...
Allen, Kaitlin, Bartunek, Jozef, Beerens, Manu, Bloch, Donald B, Bloch, Kenneth D, Brouckaert, Peter, Buys, Emmanuel S, Caluwe, Ellen, Gillijns, Hilde, Janssens, Stefan P, Nathan, Daniel I, Scherrer-Crosbie, Marielle, Swinnen, Melissa, Tainsh, Robert E, Vandenwijngaert, Sara, Walravens, Ann-Sophie   +15 more
core   +1 more source

Synergistic Effects of Normal‐Range Serum Sodium and Potassium on Mortality: The Modifying Role of Inflammation From a NHANES Cohort Analysis

Chronic Diseases and Translational Medicine, EarlyView.
Nonlinear associations of serum sodium levels with cardiovascular (A) and all‐cause mortality (B)among 32,837 adults. Nonlinear associations of serum potassium levels with cardiovascular (C) and all‐cause mortality (D) among 32,837 adults. ABSTRACT Background This study aimed to investigate the associations of serum sodium and potassium levels within ...
Haofeng Zhang, Fudong He, Zhenger Fang, Guangjun Zheng, Biying Zhou, Xia Chen, Mingliang Liu, Guang Hao   +7 more
wiley   +1 more source

P.15 Isolated Systolic Hypertension and Central Blood Pressure: Implications from the National Nutrition and Health Survey in Taiwan

Artery Research, 2020
Objectives: We aimed to investigate the association between isolated systolic hypertension (ISH) and central blood pressure (BP) in a nationally representative population.
Shao-Yuan Chuang, Hsing-Yi Chang, Hao-Min Cheng, Wen-Harn Pan, Chen-Huan Chen   +4 more
doaj   +1 more source

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Association analysis of blood pressure with incident risks for thoracic and abdominal aortic aneurysms: an observational study of the UK Biobank cohort

Open Heart
Background The specific relationship between different blood pressure measures and the risk of aortic aneurysms (AA) remains unclear. Elucidating these associations would be conducive to identifying high-risk individuals and developing more effective ...
Xun Tang, Xiaofei Liu, Pei Gao, Ke Lu, Yuan Wang   +4 more
doaj   +1 more source

Nocturnal Hypertension and Attenuated Nocturnal Blood Pressure Dipping is Common in Pediatric Lupus [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2015
Hypertension is an important manifestation of systemic lupus erythematosus (SLE) but reports of prevalence vary between 20-70% in published reports of adult and pediatric patients.
J. Fallon Campbell, Sarah J. Swartz, Scott E. Wenderfer   +2 more
doaj   +1 more source

Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life. [PDF]

, 2019
Rationale: The incidence of gestational diabetes mellitus (GDM) is increasing worldwide. However, whether and how GDM exposure induces fetal programming of adult cardiac dysfunctional phenotype, especially the underlying epigenetic molecular mechanisms ...
Chen, Zewen, Gong, Lei, Li, Yong, Liu, Bailin, Xiao, Daliao, Zhang, Lubo, Zhang, Peng, Zhuang, Jian   +7 more
core  

Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath [PDF]

, 2015
BACKGROUND: Many patients have unexplained persistent dyspnea after negative computed tomographic pulmonary angiography (CTPA). We hypothesized that many of these patients have isolated right ventricular (RV) dysfunction from treatable causes.
Beam, Daren M., Courtney, D. Mark, Kabrhel, Christopher, Kline, Jeffrey A., Mastouri, Ronald, Moore, Christopher L., Nordenholz, Kristen E., O’Neil, Brian J., Plewa, Michael C., Richman, Peter B., Russell, Frances M., Smithline, Howard A.   +11 more
core   +1 more source

Comprehensive exploration of unexplained dyspnoea in subjects with normal ejection fraction and low natriuretic peptides

ESC Heart Failure, Volume 12, Issue 2, Page 879-887, April 2025.
Abstract Background Unexplained exertional dyspnoea without significant elevation of natriuretic peptides is common. One of the causes might be early heart failure with preserved ejection fraction (HFpEF). Aims This study aimed to characterize patients with exertional dyspnoea and normal/near‐to‐normal N‐terminal pro‐brain natriuretic peptide (NT ...
Emmanuelle Berthelot, Tarek Laouar, Antoine Beurnier, Nataliya Hrynchynshyn, Jean Christophe Eicher, Jean‐Michel Tartière, Patrick Jourdain, Olivier Lairez, Barnabas Gellen   +8 more
wiley   +1 more source