Results 51 to 60 of about 1,941,377 (263)
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. [PDF]
, 2011 The prevalence of hypertension in African Americans (AAs) is higher than in other US groups; yet, few have performed genome-wide association studies (GWASs) in AA.Keating, BJ, Boehnke, M., Lawrence, Robert W, Ridker, P.M., Alexander, M., Elosua, R., Zukowska-szczechowska, E., Philip Howard, Boerwinkle, E., Dong, Y., Parker, A.N., van der Schouw, Y.T., Hicks, Andrew A, Palmer, L.J., Zukowska-Szczechowska, Ewa, Palmer, N.D., Chris O'Donnell, Mangino, M., Colin A. McKenzie, Milaneschi, Yuri, Yen-Pei C. Chang, Toshiko Tanaka, Young, J. Hunter, Martin, Lisa W., Rettig, Rainer, Sudha Seshadri, Polak, J. F., Lathrop, Mark, Marmot, M. G., Josef F. Polak, Maciej Tomaszewski, Longstreth, Will T, Cooper, Richard S, Hedblad, Bo, Kuznetsova, T., Groop, L., Steve E. Humphries, Cooper, Richard S., Barroso, Inês, Rick Twee-Hee Ong, Cooper, J. A., Yoshikuni Kita, Ong, R.T., Loos, Ruth J F, Hugh Watkins, Vinay, D G, Chambers, John C, Schwartz, Steven M, Tai, E.S., Charles S. Janipalli, Janos Terzic, Mika Ala-Korpela, Altshuler, D., Keating, B., Maris Laan, Hofman, A., Igl, W., Daniel L. Dries, Smith, Albert V, Ongen, Halit, Thomas H. Mosley, Grassler, J., Seielstad, Mark, Heyo K. Kroemer, Miki, T., Vartiainen, Erkki, Steinle, N.I., Markku Laakso, EchoGen consortium, [Unknown], Keating, Brendan J, Ludwig, Barbara, Chang, Yen-Pei C, Bergman, R.N., Salako, T., Brand, E., Iwai, N., Salomaa, Veikko, Joel N. Hirschorn, Collins, Francis S, Go, M.J., Johnson, T, Wichmann, H.- E., Farlow, Deborah N., Hopewell, J. C., Hunt, S.C., Sue Shaw-Hawkins, Kurt K. Lohman, Orru, Marco, Najjar, S., Lehtimäki, Terho, Lori L. Bonnycastle, Tripathy, Vikal, Abbas Dehghan, Solomon K. Musani, Uitterlinden, Andre G, et al., Cuno S.P.M. Uiterwaal, Andrew D. Johnson, Valur Emilsson, Wong, T. Y., Larson, M. G., Mosley, Thomas H, Benjamin F. Voight, Laan, M., Navis, G., Michiel L. Bots, Farlow, D. N., Nalls, M.A., Zhang, W., Rice, K.M., Gyllensten, Ulf B, Mani, K Radha, Wyatt, S. B., Vitart, Veronique, Emilsson, V., Johannes Kettunen, Hercberg, S., Brown, Morris J, Nguyen, Khanh-Dung Hoang, Michael G. Marmot, Rao, D. C., John C. Chambers, Voight, B. F., Franceschini, N, Aravinda Chakravarti, Scuteri, Angelo, Lucas, Gavin, Sun, Y.V., Khanh-Dung Hoang Nguyen, Santhi Ganesh, Dominiczak, Anna F, Caulfield, M.J., Wright, A.F., Talmud, Philippa J, Forrester, Terrence, Kooner, J.S., Robert W. Lawrence, Cooper, M. N., Hadley, D., Gaunt, T.R., Lyon, HN, Fernando Rivadeneira, Jaakko Tuomilehto, Talmud, P.J., Gyllensten, U. B., George Davey Smith, Ulf B. Gyllensten, Lyon, Helen N, Longstreth, W.T., Shih-Jen Hwang, Wareham, N.J., Eaton, C. B., Li, Y., Toshio Ogihara, Kooner, Jaspal S, Giuseppe Matullo, Peter P. Pramstaller, Pihur, V., Steinle, N. I., Burton, P.R., Heath, S., Mariacorsi, A., Verwoert, G. C., Erdmann, Jeanette, Nicholas J. Wareham, Eva Brand, Samani, N. J., Artigas, M.S., Sharma, Pankaj, Xiaofeng Zhu, Galan, P., Li, YL, van Gilst, Wiek H, Van Der Harst, P., Vineis, P., Collins, F.S., Tai, E Shyong, Jackson, A.U., Grässler, Jürgen, Wilson, James F, Palmer, Lyle J, Danish Saleheen, Whincup, P.H., Lee, J.-y., Tukiainen, T., Okamura, T., Garcia, M., Dong, Yanbin, Dorairajan Prabhakaran, Judith A. Hoffman Bolton, Kang, S.J., Casas, J. P., Dehghan, Abbas, Kroemer, H. K., KidneyGen consortium, [Unknown], Penman, Alan D., Bamidele O. Tayo, Melissa Garcia, Verwoert, Germaine C, Perola, Markus, Cristian Pattaro, Köttgen, Anna, Rice, K. M., Alex N. Parker, Vinay, DG, Islam, M., McKenzie, Colin A, Van Der Schouw, Y. T., Toby Johnson, Meschia, James F, Hercberg, Serge, Longstreth, W. T., Pramstaller, P. P., Parker, A. N., Bornstein, S. R., Beckmann, Jacques S, Hicks, A.A., Min JinGo, Volker, U., Susana Eyheramendy, Fox, Ervin R., Hartikainen, A.-l., Will T. Longstreth, Townsend, R.R., Brand, Eva, Jacques S. Beckmann, Anna-Liisa Hartikainen, Polasek, Ozren, Kumari, M., Nish Chaturvedi, Lynne E. Wagenknecht, Polak, J., Louise V. Wain, Tzoulaki, I., Jing Hua Zhao, Soininen, P., Penman, A. D., Sehmi, J.S., Anna Köttgen, Mosley, Thomas H., Luan, J., Cristiano Fava, Rotter, J.I., Steven C. Hunt, Psaty, B. M., Alanna C. Morrison, Ehret, Georg B, Gavin Lucas, Debbie A. Lawlor, Hoffman Bolton, Judith A, Heckbert, S. R., Umemura, Satoshi, Mosley, T.H., Wild, Sarah H, Jackson, Anne U, Townsend, RR, Raitakari, Olli, JinGo, Min, Rudan, I., Snieder, Harold, Stephan J.L. Bakker, Thomas J. Wang, Annika Rosengren, Stancakova, A., Fabsitz, R. R., Connell, John M, Kangas, A.J., Eyheramendy, Susana, Tim D. Spector, Palmas, W, Dag S. Thelle, Megan E. Rudock, Van Gilst, W. H., Stancáková, Alena, Thor Aspelund, Shaw-hawkins, S., Ehret, G. B., Hernandez, Dena, Shrine, N.R., Ramachandran, Vasan S, Oostra, Ben A, Andrew Taylor, Kivimaki, M., Chen, M.H., Hyung-Lae Kim, Keating, B. J., Kooner, J. S., Zhao, J. H., Yajnik, C. S., Volzke, H., Wilmar Igl, Dominiczak, A. F., Laakso, Markku, Peden, J. F., Ewa Zukowska-Szczechowska, Jaspal S. Kooner, Polak, JF, Smita R. Kulkarni, Thomas Meitinger, Coresh, J., Hadley, David, Zhu, Haidong, Kardia, S. L. R., Elliott, P., O'Connell, Jeffrey R, Laitinen, J., Veldre, G., Palmer, L. J., Nanette I. Steinle, Casas, J.P., Palmas, W., Hilton, Gina, Helen N. Lyon, Swift, A. J., Bornstein, Stefan R, Altshuler, David, Matthias Olden, Chen, M.-h., Rotimi, C. N., Doumatey, AP, Newton-cheh, C., Francis S. Collins, Hwang, Shih-Jen, Uiterwaal, C.S., Luan, Jian'an, Chandak, G. R., Launer, Lenore, Salako, Tunde, Panos Deloukas, Stringham, Heather M, Najaf Amin, Farlow, DN, Beilby, John P, Vinay, D. G., Smith, N.L., Jennifer L. Bragg-Gresham, Elosua, Roberto, Caulfield, Mark J., Dries, D. L., Tuomilehto, J., Swift, Amy J, Uiterwaal, C. S. P. M., Taylor, Herman A, Munroe, Patricia B, Serge Hercberg, Morrison, Alanna C, Fadi J. Charchar, Arfan Ikram, M., Germaine C. Verwoert, Bok-Ghee Han, Sharon B. Wyatt, Soininen, Pasi, Kardia, Sharon L R, Carl D. Langefeld, Andrew A. Hicks, Farlow, D., Bis, Joshua C, Kang, Sun J., Roberto Elosua, Andre G. Uitterlinden, Curb, J. David, Ehret, G.B., Albert W. Dreisbach, Prabhakaran, D., Salomaa, V., Parsa, Afshin, Dreisbach, AW, Dries, DL, Mohlke, K.L., Campbell, Harry, Platou, C. G. P., Kinra, S., Nguyen, K.-d. H., Hirschorn, J.N., Kivimaki, Mika, Narisu, Narisu, Hingorani, A.D., Afshin Parsa, Johnson, A.D., Fabsitz, R.R., Vollenweider, P., Rasheed, Asif, Linda S. Adair, Voight, Benjamin F, Kardia, SLR, Scott, J., Cho, Y. S., Guo, X., Newton-Cheh, Christopher, Mcardle, W. L., Kuh, Diana, Leena Peltonen, Arking, D.E., McKenzie, C.A., Bochud, M., Wain, L. V., Dries, D., Plump, A., Kulkarni, Smita R, Nilsson, Peter, Meitinger, T., Doumatey, Ayo P, Ozren Polasek, Dreisbach, A., Jeanette Erdmann, Mario A. Morken, Parsa, A., Takayoshi Ohkubo, Kardia, Sharon L.R., Han, Bok-Ghee, Shrine, N. R. G., Albert V. Smith, Smith, A.V., Gonçalo R. Abecasis, Yajnik, C.S., Rosengren, A., Inga Prokopenko, David P. Strachan, Nora Franceschini, Wareham, Nicholas J, Young, J.H., Stringham, H. M., Adeyemo, A, Barroso, I., Smith, G.D., Jan A. Staessen, Kita, Y., Franceschini, N., Nalls, M. A., Vilmundur Gudnason, Tetsuro Miki, Smith, G. D., Lohman, K.K., Guangju Zhai, Young, J Hunter, Mattace-Raso, Francesco U S, Tom R. Gaunt, Alexander, Myriam, Zhu, X, Hingorani, A. D., Langefeld, C.D., Ramachandran, V.S., Lyytikäinen, Leo-Pekka, Wang, Thomas J, Doumatey, Ayo P., Bis, J.C., Wilson, J.F., Okamura, Tomonori, Myriam Alexander, Gerjan Navis, Mattace-raso, F. U. S., Raitakari, O., Rudock, Megan E, International Consortium for Blood Pressure Genome-Wide Association Studies, Connell, J. M., Feng Zhang, Adair, L. S., Beckmann, J. S., Lyytikäinen, L.P., Wong, Tien Y, Gina Hilton, E. Shyong Tai, Scott, Laura J, Peltonen, Leena, Lohman, K. K., Soranzo, N., John F. Peden, Dominiczak, A.F., Charchar, F. J., Tayo, B.O., Dreisbach, Albert W., Lawlor, D.A., Rotter, J. I., Kahonen, M., Boehnke, Michael, Ian N.M. Day, Palmas, Walter, Campbell, H., Eaton, CB, Coresh, Josef, Scott, James, Barbara Ludwig, Heather M. Stringham, Isaacs, A., O'reilly, P. F., Bergman, R. N., CARDIoGRAM consortium, [Unknown], Zitting, Paavo, Hwang, S.J., Levy, D, Wilson, James F; id_orcid, Corsi, Anna Maria, Shuldiner, A. R., O'Reilly, P.F., Lawrence, R. W., Bergmann, S., Pattaro, C., Khaw, K.-t., Stefan R. Bornstein, Collins, R., Frayling, Timothy M, Farrall, M., Teumer, Alexander, Umemura, S., Matullo, G., Martin, Lisa W, Pattaro, Cristian, Leo-Pekka Lyytikäinen, Li, Y, Ehret, Georg B., Nicole L. Glazer, Aroon D. Hingorani, Abecasis, Gonçalo R, Emilsson, Valur, Gaunt, T. R., Tomonori Okamura, Heckbert, S.R., Ming-Huei Chen, Ramachandran, V. S., Gang Shi, Wendy L. McArdle, Collins, F. S., Jutta Palmen, Nilesh J. Samani, Lakatta, Edward G, Veikko Salomaa, Townsend, R. R., Fava, C., Wang, T.J., Lawlor, D. A., Morrison, A., Chambers, J.C., Khaw, Kay-Tee, Yurii Aulchenko, Wu, Ying, Wain, L.V., Chandak, Giriraj R, Muhammad Islam, Viigimaa, M., Day, I.N., Raffel, Leslie J, Kristian Hveem, Taylor, A., Liu, Yongmei, Gerald R. Fowkes, Musani, Solomon K, Soler Artigas, Maria, Samani, Nilesh J, Sekar Kathiresan, Kardia, S.L., Musani, Solomon K., Alan B. Weder, Hirschhorn, J.N., McArdle, W.L., Vollenweider, Peter, Melander, O., Meneton, P., Cooper, J.A., Wong, T.Y., Morrison, AC, Soranzo, Nicole, Hayward, Caroline, Palmer, N. D., Albert Hofman, Ohkubo, T., O'Donnell, Chris, Zelenika, Diana, Voight, B.F., Redline, Susan, Yali Li, Igl, Wilmar, Wild, S. H., Kottgen, A., Morris J. Brown, Farlow, D.N., Iwai, Naoharu, Würz, Peter, Gieger, Christian, Yao, Jie, Kroemer, H.K., Ala-Korpela, Mika, Rotimi, C.N., Viikari, Jorma, Penman, Alan D, Caulfield, MJ, Sim, X., Simonetta Guarrera, Bonnycastle, L.L., Bakker, S. J. L., Mosley, T. H., Kranthi Kumar, M. J., Lyle J. Palmer, M.J. Kranthi Kumar, Fox, E.R., Liu, Kiang, Chakravarti, Aravinda, Fredrik Nyberg, Schwartz, S.M., John M. Connell, Kuusisto, Johanna, Wagenknecht, L.E., Morken, M.A., Adeyemo, A., Alexander Teumer, Alan R. Shuldiner, Grobbee, D. E., Morris, Richard W, Lakatta, E.G., Amin, N., Nyberg, Fredrik, Dreisbach, A.W., Oostra, B.A., Mika Kivimaki, Watkins, Hugh, Morrison, A.C., Harris, T. B., Meschia, J. F., Christian Gieger, Sijbrands, E. J. G., Bergman, Richard N, J. David Curb, Polak, Josef F., Thelle, Dag S, Morken, Mario A, Ioanna Tzoulaki, Raymond R. Townsend, Jafar, T.H., Aspelund, Thor, Polak, J.F., Michael Boehnke, Redline, S., Jackson, A. U., Viigimaa, Margus, Saleheen, Danish, Kim, H.-l., Hardy, Rebecca, Spector, T.D., Sijbrands, E.J., Forrester, T., Navis, Gerjan, Howard, P., Isaacs, Aaron, Verwoert, G.C., Rice, Kenneth M, Kathiresan, Sekar, Larson, Martin G, Tomaszewski, M., Hingorani, Aroon D, Lakatta, E. G., Markus Perola, Loos, R.J., Gyllensten, U.B., Alena Stančáková, Perola, M., Peter Nilsson, Jemma C. Hopewell, Alan D. Penman, Ruth J.F. Loos, Staessen, J. A., Ala-korpela, M., Haidong Zhu, Fabsitz, Richard R, Francesco U.S. Mattace-Raso, Musani, S.K., Abecasis, G. R., Tien Y. Wong, Aulchenko, Yurii, Robert Clarke, Maria SolerArtigas, Jafar, Tazeen H, Arora, P., Chasman, D.I., Janipalli, C. S., Karen L. Mohlke, Kangas, Antti J, Dabeeru C. Rao, Hwang, S.-j., Adair, Linda S, N. Charlotte Onland-Moret, Richard S. Cooper, Anne U. Jackson, Kulkarni, S.R., Gaunt, Tom R, Kutlar, A., Sõber, Siim, Lee, N.R., Leif Groop, Wain, Louise V, Yan V. Sun, Hopewell, J.C., Prabhakaran, Dorairajan, Palmen, J., Staessen, Jan A, Bragg-gresham, J. L., Lucas, G., Terho Lehtimäki, Nanette R. Lee, Fowkes, G. R., Tuomilehto, Jaakko, Paolo Vineis, Solerartigas, M., Richard W. Morris, Kumari, Meena, Eric J.G. Sijbrands, Eaton, C.B., Asif Rasheed, Vartiainen, E., Uda, M., Kroemer, Heyo K, Susan R. Heckbert, Connell, J.M., Ehret, GB, Eaton, Charles B., Morken, M. A., Harris, Tamara B, Kathiresan, S., O'Reilly, Paul F, Amin, Najaf, Kettunen, Johannes, Ganesh, S., Chang, Y.-p. C., H.-Erich Wichmann, Langefeld, Carl D, Elliott, Paul, Zhai, G., Siim Sõber, Dorr, M., Shi, Gang, Shrine, Nick R G, Zhu, H., Kenneth M. Rice, Humphries, S.E., Kardia, SL, Laan, Maris, J. Hunter Young, Bots, M. L., Pankaj Sharma, Vikal Tripathy, Cooper, Matthew N, Samani, N., Peter Vollenweider, Hicks, A. A., Terzic, J., Ganesh, S, Yoon Shin Cho, Ben A. Oostra, Swift, A.J., Eaton, Charles B, Schwarz, P. E. H., Manuela Uda, Matullo, Giuseppe, Sehmi, J. S., Palmer, Nicholette D, Demirkan, A., Bochud, Murielle, Weder, A.B., Boerwinkle, Eric, Humphries, Steve E, Jacqueline C.M. Witteman, Beilby, J.P., Wyatt, Sharon B, Wichmann, H.E., Martin Farrall, Hveem, K., Martin D. Tobin, Paul R. Burton, Mooser, Vincent, Mohlke, K. L., Curb, J David, Cooper, M.N., Heckbert, Susan R, Eyheramendy, S., Bandinelli, S., Taylor, HA, Orru, M., Tayo, BO, Hunt, S. C., Ervin R. Fox, Aspelund, T., Liu, K, Morrison, A. C., Levy, Daniel, Tamara B. Harris, oel, Anuj, Wichmann, H-Erich, Cooper, RS, Bonnycastle, L. L., Wong, A., Taylor, H. A., Xueling Sim, Watkins, H., Charchar, F.J., Nicholette D. Palmer, Wagenknecht, L. E., Wright, Alan F, Diederick E. Grobbee, ICBP Consortium (Meitinger, T. ; Wichmann, H.-E.), Vineis, Paolo, Brown, M.J., Narisu, N., Mark J. Caulfield, Yuri Milaneschi, Ueshima, Hirotsugu, Jerome I. Rotter, Lee, J.Y., Danesh, J., Bots, Michiel L, Sanjay Kinra, Paul M. Ridker, Campbell, Harry; id_orcid, Wiggins, K.L., Kuznetsova, Tatiana, Chandak, G.R., Chasman, Daniel I, Johnson, A. D., Peter S. Braund, Singleton, Andrew, Lehtimaki, T., Ridker, P. M., Johnson, T., Tazeen H. Jafar, ?, ?, Zhao, Jing Hua, Kao, W. H. L., O'donnell, C., Kao, Wen Hong Linda, Witteman, Jacqueline C M, Townsend, Raymond R., Martin G. Larson, Shuldiner, A.R., Rudock, M.E., Rotimi, Charles N, Mark Lathrop, Arking, Dan E, Musani, SK, Musani, S., Seshadri, S., Platou, C.G., Tzoulaki, Ioanna, Hilton, G., Fowkes, F Gerald R, Mark Seielstad, Caulfield, M. J., Wiggins, Kerri L, Uda, Manuela, John P. Beilby, Ying Wu, Guo, Xiuqing, Bandinelli, Stefania, Bakker, S.J., Prokopenko, Inga, International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), Fulvio Ricceri, Dena Hernandez, Narisu Narisu, Ikram, M Arfan, Bergmann, Sven, Daniel I. Chasman, Rasheed, A., Tobin, M.D., Richard R. Fabsitz, Adair, L.S., Martin, LW, Scuteri, A., Palmen, Jutta, Adebowale Adeyemo, Abecasis, G.R., Sun J. Kang, Rao, Dabeeru C, Dreisbach, Albert W, Chittaranjan S. Yajnik, Peter Würz, Rotimi, CN, Taru Tukiainen, Ueshima, H., Wurz, P., Rotter, Jerome I, Chen, Ming-Huei, Alan F. Wright, Kang, S. J., Kuh, D., Franceschini, Nora, Andrew Wong, Goel, A., Stringham, H.M., Lyon, H. N., Marco Orru, Janipalli, C., Vincent Mooser, Curb, J. D., Fox, E., Kardia, Sharon LR, Andrew Singleton, Curb, J.D., Laakso, M., Hunt, Steven C, Dörr, Marcus, Juan P. Casas, Terzic, Janos, Erdmann, J., Arora, Pankaj, Murielle Bochud, Vasyl Pihur, Kuusisto, J., van Duijn, C.M., Philippa J. Talmud, Wagenknecht, Lynne E, Levy, D., Chambers, J. C., Parker, Alex N, Sjögren, Marketa, Simon Heath, Paavo Zitting, Fowkes, F.G., Raffel, L.J., Hirschorn, Joel N., Anders Hamsten, Bornstein, S.R., Adeyemo, Adebowale, van der Harst, Pim, Loos, R. J. F., Jafar, T. H., Sun, Yan V, Luigi Ferrucci, Ludwig, B., Corsi, A.M., Schwarz, P.E., Kähönen, Mika, Tobin, Martin D, Anuj Goel, Paul Elliott, Sun, Yan V., Mika Kähönen, Witteman, J. C. M., Jie Yao, Uitterlinden, A. G., Stefan-Martin Brand, Deloukas, P., Wang, T. J., Fox, ER, Weder, Alan B, Frayling, T. M., Dehghan, A., CKDGen consortium, [Unknown], Guarrera, Simonetta, Teumer, A., Pim van der Harst, Joban S. Sehmi, James Scott, Andrew Plump, Wareham, N. J., Sjogren, M., Beckmann, J.S., Bragg-Gresham, J.L., Kao, W.H., Kinra, Sanjay, Shuldiner, Alan R, Plump, Andrew, Daniel Levy, Polasek, O., Lohman, Kurt K, Hirschorn, J. N., Wyatt, S.B., International Consortium for Blood Pressure Genome-wide Associat, Munroe, P.B., Kita, Yoshikuni, Amy J. Swift, Kutlar, Abdullah, Wild, Sarah H; id_orcid, Jackie A. Cooper, Taylor, Andrew, Grobbee, Diederick E, Nalls, Michael A, Seielstad, M., Ayo P. Doumatey, Wu, Y., Zhang, Feng, Glazer, N. L., David Altshuler, Marmot, Michael G, Deloukas, Panos, Rosengren, Annika, Twee-hee Ong, R., Ohkubo, Takayoshi, Margus Viigimaa, O'Connell, J.R., Steinle, Nanette I, Laura J. Scott, Saleheen, D., Laitinen, Jaana, Rory Collins, Jarvelin, M.-r., Burton, P. R., Go, Min Jin, Collins, Rory, Talmud, P. J., Kim, H.L., Hofman, Albert, Zhao, J.H., Yongmei Liu +999 morecore +2 more sourcesIntegrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue +10 morewiley +1 more sourcePhenotypes of Hypertension: Impact of Age and Sex on Hemodynamic Mechanisms
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Essential hypertension is often treated as a uniform condition. However, it encompasses distinct patterns of blood pressure elevation such as isolated systolic, systolic diastolic, and isolated diastolic hypertension, which vary in prevalence ...Domonkos Cseh, Yasmin, Barry J. McDonnell, Kaisa M. Mäki‐Petäjä, Taylor Simonian, John R. Cockcroft, Ian B. Wilkinson, Carmel M. McEniery +7 moredoaj +1 more sourceRe‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT
Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil +9 morewiley +1 more source
