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Treatment of Isolated Systolic Hypertension in the Elderly

Journal of Cardiovascular Pharmacology, 1991
Isolated systolic hypertension affects between 10 and 20% of the elderly population and carries a substantial risk of cardiovascular complications. As no prospective, randomized trials have produced scientific evidence of a treatment benefit in elderly patients with isolated systolic hypertension, opinion on when and how to treat this condition differs
J, Staessen   +6 more
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Clinical trials in isolated systolic hypertension

Current Hypertension Reports, 1999
Isolated systolic hypertension affects 8% to 15% of all people older than 60 years of age. In the elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three placebo-controlled outcome trials on antihypertensive drug treatment of this disorder have been published.
J, Gasowski, J G, Wang, J A, Staessen
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Isolated Systolic Hypertension

2017
ISH is diagnosed when systolic blood pressure is more than 140 mmHg with a normal or low diastolic pressure (less than 90 mmHg). Prevalence of ISH increases with age, and it is one of the special problems in hypertension among geriatric population. Contrary to traditional thinking, systolic hypertension is a strong predictor of cardiovascular
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Determinants of isolated systolic hypertension in the elderly

Journal of Hypertension, 1992
To study the determinants (or mechanisms) of isolated systolic hypertension in the elderly.Pulsatile blood pressure and flow (multisensor catheter) were measured in the ascending aorta and impedance spectra were calculated in 18 subjects undergoing cardiac catheterization. Nine subjects (mean +/- SEM age 58 +/- 1.4 years) had increased aortic systolic (
W W, Nichols, F A, Nicolini, C J, Pepine
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Treating Isolated Systolic Hypertension in the Elderly

Annals of Pharmacotherapy, 1994
OBJECTIVE: To review the prevalence, pathophysiology, vascular risk, and treatment of isolated systolic hypertension (ISH) in the elderly. DATA SOURCE: A MEDLINE search of the English language literature was performed to identify ...
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Management of Isolated Systolic Hypertension in the Elderly

Journal of the American Geriatrics Society, 1986
Now that the benefits of treating diastolic hypertension in the elderly have been convincingly proved, attention is turning to the need for, and the choice of, treatment of isolated systolic hypertension in this age group. The hemodynamic mechanism differs in the elderly, whose isolated systolic hypertension is likely to be accompanied by reduced ...
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Controlling isolated systolic hypertension

Postgraduate Medicine, 1999
Isolated systolic hypertension (ISH) is the most common form of hypertension in the elderly. It is an even better predictor of morbidity and mortality than is diastolic blood pressure. Several large trials have documented a clear benefit to treating ISH.
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Treatment of isolated systolic hypertension in the elderly

Expert Review of Cardiovascular Therapy, 2012
Systolic hypertension is a major health economy problem within our aging society. Increased arterial stiffness is the vascular phenotype of systolic hypertension, especially of the large arteries. Elevated systolic blood pressure is even more associated with cardiovascular morbidity and mortality than diastolic blood pressure.
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Isolated systolic hypertension

Anaesthesia, 2002
M. McSwiney, C. Mather
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Isolated systolic hypertension

DMW - Deutsche Medizinische Wochenschrift, 2005
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