Results 121 to 130 of about 102,137 (247)

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

¹⁹F-NMR spectroscopy of fluorinated isoleucine analogues in a protein. [PDF]

J Biomol NMR
Welegedara AP, Tan YJ, Borgini M, Wipf P, Otting G.   +4 more
europepmc   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Construction of Escherichia coli L-isoleucine cell factories based on propionate pathway. [PDF]

J Biol Eng
Xiao Y, Li X, Jiang L, Zhao Y, Wang L, Feng Y.   +5 more
europepmc   +1 more source

Proteome Analysis of Corynebacterium diphtheriae–Macrophage Interaction

PROTEOMICS, EarlyView.
ABSTRACT Contact of Corynebacterium diphtheriae with macrophages induces adaptations on both bacterial and cellular sides. The study presented here was aiming to shed light on the simultaneous intracellular adaptation of the bacteria and changes in the proteome of the phagocytes in response to the internalization of C. diphtheriae.
Luca Musella, Jens Möller, Christopher Lischer, Julio Vera‐Gonzalez, Jörg Hofmann, Lisa Ott, Andreas Burkovski   +6 more
wiley   +1 more source

Isoleucine and valine regulate the BCAA antagonism by influencing insulin function in broiler chickens. [PDF]

J Anim Sci Biotechnol
Wang B, Zhang X, Li G, Gao M, Feng Y, He Y, Guo Y.   +6 more
europepmc   +1 more source

Reduction in Synaptic Vesicle Protein Abundance but Increased Amounts of Nsg2 and Lpcat1 in Cerebral Cortices Without the Endosomal SNARE Proteins Vti1a and Vti1b

PROTEOMICS, EarlyView.
ABSTRACT Absence of the endosomal SNAREs vti1a and vti1b results in perinatal death and severe neuronal phenotypes in mice, while lack of one of these proteins results in minor phenotypes. Proteomic differences were investigated to obtain a deeper insight into processes in which vti1a and vti1b are involved.
Julia Gottschalk, Katharina Kotschnew, Julia Hahn, Thomas Patschkowski, Gabriele von Fischer von Mollard   +4 more
wiley   +1 more source

Association and predictive value of blood branched-chain and excitatory amino acids with autism spectrum disorder severity. [PDF]

BMC Pediatr
Li J, Wang Y, Bi L, Yang X, Yang Y, Zhang Q, Mei X, Dang W, Feng G, Zhang X, Zhou R.   +10 more
europepmc   +1 more source

Engineering Crosslinker‐Free Sericin–Gelatin Hydrogels With Tunable Rheology for 3D Printing Applications

Journal of Polymer Science, EarlyView.
Gelatin derived from porcine tissue and sericin extracted from Bombyx mori cocoons are combined to form crosslinker‐free hydrogels with tunable composition, enabling extrusion‐based 3D printing and biocompatible constructs for biomedical applications. ABSTRACT Hydrogels can be processed by 3D printing to manufacture tailor made structures, broadening ...
André S. Macedo, Alaitz Etxabide, Teresa Carranza, Ricardo Brito‐Pereira, Clarisse Ribeiro, Pedro Guerrero, Koro de la Caba, Senentxu Lanceros‐Méndez   +7 more
wiley   +1 more source

Effects of <i>Astragalus membranaceus</i> and <i>Panax notoginseng</i> Saponins Extract on the Pharmacokinetics of Whey Protein Absorption, Intestinal Permeability, and Muscle Function: A Pilot Study. [PDF]

Nutrients
Zhuang SR, Yen CH, Lin KY, Shen YC.
europepmc   +1 more source