Results 121 to 130 of about 183,864 (337)
Journal of the agricultural chemical society of Japan, 1962 不飽和カルボン酸に対するグリニヤール試薬の1, 4付加反応をイソロイシンの合成に応用し,新合成法を確立した.すなわち,クロトン酸およびそのsec-ブチルエステルにエチルマグネシウムブロミドを作用せしめた後,その反応コンプレックスにハロゲンを付加し,得られたα-ハロゲンカルボン酸をアミノ化してイソロイシンを合成した.なお,この際グリニヤールコンプレックスへのヨウ素付加においてスレオ型が優先して生ずることより,その付加が隣接基の立体効果をうける現象を認めた.
openaire +2 more sources
Advanced Science, EarlyView.ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin +9 more
wiley +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study investigates the prognostic utility of a novel volumetric indicator—psoas volume index (PVI)—for assessing sarcopenia in elderly rectal cancer patients. Sarcopenia classified by our proposed PVI cut‐off values was associated with poor nutritional and inflammatory status, and patients with low PVI showed significantly worse long‐term outcomes.
Gen Tsujio +8 more
wiley +1 more source
Investigating the biological relevance in trained embedding representations of protein sequences [PDF]
, 2019 As genome sequencing is becoming faster and cheaper, an abundance of DNA and protein sequence data is available. However, experimental annotation of structural or functional information develops at a much slower pace.
De Neve, Wesley +4 more
core +1 more source
Hydrogen bonds and asymmetrical heat diffusion in a-Helices. A Computational Analysis
, 2015 In this work, we report the heat rectifying capability of a-helices. Using molecular dynamics simulations we show an increased thermal diffusivity in the C-Terminal to N-Terminal direction of propagation.
Gutierrez, Gonzalo +1 more
core +2 more sources
Animal Research and One Health, EarlyView.Palatability enhancers modulate taste and smell, increasing feed acceptance, reducing weaning stress, and improving piglet performance. ABSTRACT The continuous growth of global agribusiness stimulates the search for alternatives that can enhance the performance and quality of life of production animals.
Luana Specht +3 more
wiley +1 more source
The Oxylipin Signal Jasmonic Acid Is Activated by an Enzyme That Conjugates It to Isoleucine in Arabidopsis[W] [PDF]
, 2004 Paul Staswick, İskender Tiryaki
openalex +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Isobutanol is a fusel alcohol that can be produced microbially for use as a biofuel or upgraded into sustainable aviation fuel (SAF). A key enzyme in the isobutanol biosynthetic pathway is 2‐ketoacid decarboxylase (KDC), which irreversibly decarboxylates 2‐ketoisovalerate (KIV) to yield isobutyraldehyde.
Joshua J. Dietrich +6 more
wiley +1 more source
Uptake of branched-chain alpha-keto acids in \u3ci\u3eBacillus subtilis\u3c/i\u3e [PDF]
, 1976 Bacillus subtilis has a constitutive system for the uptake of alpha-keto-beta-methylvalerate, alpha-ketoisovalerate, and (probably) alpha-ketoisocaproate.
Goldstein, Barry J., Zahler, Stanley A.
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The Effect of Branched Chain Amino Acids on the Synthesis of Isoleucine from Threonine and Pyruvate in Crude Extracts from Escherichia coli. [PDF]
, 1970 Raimo Raunio +4 more
openalex +1 more source