Results 161 to 170 of about 105,135 (263)

CYCLOPENTANEGLYCINE, AN INHIBITORY ANALOGUE OF ISOLEUCINE

open access: yesJournal of Biological Chemistry, 1954
W M, HARDING, W, SHIVE
openaire   +2 more sources

Common pathways and outliers in glucose catabolism across Trypanosomatidae

open access: yesThe FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes   +5 more
wiley   +1 more source

Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance

open access: yesThe FEBS Journal, EarlyView.
Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley   +1 more source

GSK3α‐mediated regulation of the RNA demethylase fat mass and obesity‐associated protein (FTO) during murine spermatogenesis

open access: yesThe FEBS Journal, EarlyView.
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari   +7 more
wiley   +1 more source

pCODE tRNA Expression Plasmids Compensate for Rare Codons in Recombinant Protein Production. [PDF]

open access: yesACS Synth Biol
Feller M   +6 more
europepmc   +1 more source

Targeted keratin repair: A plant‐based approach to hair strength and surface restoration

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge   +6 more
wiley   +1 more source

Trial-ready external controls for gene therapy: The MATCH cohort in maple syrup urine disease. [PDF]

open access: yesCell Rep Med
Brigatti KW   +9 more
europepmc   +1 more source

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