Hypertension incidence according to branched-chain amino acid intake in Brazilian adults: a six-year follow-up of the CUME study. [PDF]
da Silva FMO +4 more
europepmc +1 more source
CYCLOPENTANEGLYCINE, AN INHIBITORY ANALOGUE OF ISOLEUCINE
W M, HARDING, W, SHIVE
openaire +2 more sources
Common pathways and outliers in glucose catabolism across Trypanosomatidae
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes +5 more
wiley +1 more source
Effect of Amino Acid Substitutions at Site F397 on the Kinetic and Thermostability Properties of <i>Paenibacillus polymyxa</i> β-Glucosidase B. [PDF]
Yanes A +3 more
europepmc +1 more source
Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance
Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley +1 more source
Branched-Chain Amino Acids Mediate the Regulation of SACE_Lrp on the Aminotransferase IlvE Involved in Erythromycin Biosynthesis in Saccharopolyspora erythraea. [PDF]
Cai X +9 more
europepmc +1 more source
FTO regulates mRNA stability and translational efficiency through its m6A‐demethylation activity. GSK3 functions as an upstream regulator of FTO, leading to its inhibition via phosphorylation. In male germ cells, FTO activity is kept in check by GSK3α.
Neha Choudhari +7 more
wiley +1 more source
pCODE tRNA Expression Plasmids Compensate for Rare Codons in Recombinant Protein Production. [PDF]
Feller M +6 more
europepmc +1 more source
Targeted keratin repair: A plant‐based approach to hair strength and surface restoration
Application of Avena strigosa seed extract may reinforce keratin bonding, restoring hair fibre integrity by promoting intramolecular interactions at damaged sites of keratin proteins. Abstract Objective Chemical and thermal stress disrupts the intramolecular and intermolecular interactions that stabilize hair keratin, leading to structural degradation ...
Emina Besic Gyenge +6 more
wiley +1 more source
Trial-ready external controls for gene therapy: The MATCH cohort in maple syrup urine disease. [PDF]
Brigatti KW +9 more
europepmc +1 more source

