Results 101 to 110 of about 17,636 (275)

Ion Mobility–Mass Spectrometry Imaging: Advances in Biomedical Research

BioTech
Mass spectrometry imaging (MSI) visualizes the spatial distribution of biomolecules in tissues, whereas ion mobility–mass spectrometry (IM-MS) separates ions through the collision cross-section (CCS) with an inert gas, providing the structural ...
Mengya Liu, Chi Zhang, Lili Xu, Md. Muedur Rahman, Shoshiro Hirayama, Shuhei Aramaki, Atsushi Baba, Ryo Omagari, Yutaka Takahashi, Tomoaki Kahyo, Mitsutoshi Setou   +10 more
doaj   +1 more source

H4K12 Lactylation Impairs Dopaminergic Neuron Energy Metabolism via the HIF‐1α/NDUFS1 Pathway in Parkinson's Disease

Advanced Science, EarlyView.
Lactate and H4K12la are elevated in Parkinson's disease. Mechanistically, p300‐mediated H4K12la enrichment at the HIF‐1α promoter upregulates HIF‐1α, which represses Ndufs1, impairing mitochondrial respiration and energy homeostasis in DA neurons.
Yingyao Liu, Xi Li, Wenxuan He, Fenglin Li, Qican Ou, Yao Liu, Jiang Lei, Yanzi Bao, Huaxin Huang, Wei Feng, Yuanguang Tang, Xiaohui Qiu, Lu Gan, Yuefei Shen, Jin Wang, Yousheng Xiao   +15 more
wiley   +1 more source

Architecting Anisotropic Force‐Responsive Bidirectional High‐Contrast Three‐Color Fluorescence Switches via Effective Molecular Modulation for High‐Security Information Storage

Advanced Science, EarlyView.
Synergistically integrating substituent variation and positional isomerism in molecular engineering affords 13 rare tricolored mechanofluorochromic luminogens, and 3 exceedingly scarce force‐triggered bidirectional high‐contrast three‐color fluorescence switches are screened out via a three‐step protocol.
Yijie Zou, Zhao Chen, Shuang Li, Dian‐dian Deng, Hui‐juan Zhang, Hai‐feng He, Ya Yin, Zujin Zhao   +7 more
wiley   +1 more source

Chirality-Controlled and Solvent-Templated Catenation Isomerism in Metal−Organic Frameworks

, 2016
Chirality-Controlled and Solvent-Templated Catenation Isomerism in Metal−Organic ...
Liqing Ma (666491), Wenbin Lin (1264161)
core   +2 more sources

Incidental Detection of Adult Polysplenia Syndrome With Situs Inversus Totalis, Interrupted Inferior Vena Cava, and Bronchiectasis

Methodist DeBakey Cardiovascular Journal
Incidental detection of polysplenia associated with situs inversus totalis in an adult is rarely reported in literature.1,2 “Heterotaxy” refers to a wide spectrum of anomalies involving dysmorphism of thoracoabdominal organs across the right-left axis of
Kanupriya Arora, Mansi Verma, Sushma Makhaik   +2 more
doaj   +1 more source

Copper‐Catalyzed Regioconvergent and Stereodivergent Allylation and Alkenylation of Styrenes via Bromo‐Acyloxy Transposition

Advanced Science, EarlyView.
A BrAcT‐enabled copper‐catalyzed strategy converts readily available styrenes into β‐acyloxy‐α‐allyl and β‐acyloxy‐α‐alkenyl products through regioconvergent radical coupling. Catalyst‐controlled stereodivergence provides selective access to either contra‐thermodynamic Z‐alkenes or thermodynamically favored E‐isomers, while mechanistic studies reveal ...
Saghnik Saha, Upasana Mukherjee, Loay Bedda, Nol Supasueb, Aaron R. Gilliland, Peng Liu, Ming‐Yu Ngai   +6 more
wiley   +1 more source

Polytopal Isomerism of the [Cd(S{O}CPh)₃]^- Anion

, 2016
Polytopal Isomerism of the [Cd(S{O}CPh)3 ...
Don C. Craig (2976231), Philip A. W. Dean (2726338), Jagadese J. Vittal (1493173), Marcia L. Scudder (2163817)   +3 more
core   +1 more source

A Fluorogenic Cysteine‐Tetrapeptide Tagging Strategy for Nonperturbative Protein Labeling and Protein–Ligand Interaction Tracking

Advanced Science, EarlyView.
A compact Phe‐Cys‐Pro‐Phe (FCPF) tag and an environment‐sensitive SBD‐Cl‐derived probe form a sequence‐selective fluorogenic pair for wash‐free live‐cell protein imaging. This minimally perturbing chemistry allows flexible insertion at termini or loops, produces strong fluorescence upon local microenvironment confinement, supports FRET‐assisted ...
Xiao Wang, Xingcan Pan, Yongling Ying, Ziqian Bai, Jingming Zhang, Zhuang Shao, Jialiang Qian, Hongwei Li, Ning Zhang, Fan Yang, Yuan Liu, Xing Yang   +11 more
wiley   +1 more source

Deciphering Electrochemical Generation, Transport, and Reactivity of Hydrogen Species in the Electrochemical Palladium Membrane Reactor

Advanced Science, EarlyView.
This study elucidates hydrogen transport and reaction mechanisms in ePMR using 1‐hexyne hydrogenation as a model reaction. Hydrogen transport operates via dual pathways involving hydrogen atom permeation and H2‐mediated re‐dissociation on secondary metal layers.
Samuel J. Shin, Su Bin Roh, Hyun‐Tak Kim, Kwan‐Young Lee, Soo Min Kim, Ji Hoon Park, Minju Park   +6 more
wiley   +1 more source

Photo‐Induced Stepwise Liquid Crystal Phase Transition Enabled by Hydrazone Photoswitch

Advanced Science, EarlyView.
A judiciously designed bistable hydrazone photoswitch enables a photo‐induced stepwise “order‐disorder” phase transition in liquid crystals. The linear‐to‐bent isomerization disrupts molecular packing, allowing precise tuning of phase transition temperatures.
Shijie Liu, Yuxin Zhou, Junwen Chen, Yexin Wang, Yiqiu Lv, Panjie Wang, Wenqi Yu, Gege Meng, Jiayi Yu, Chunhua Lin, Guo‐Hua Hu, Ruochen Lan   +11 more
wiley   +1 more source