Results 131 to 140 of about 28,431 (272)
Angewandte Chemie, EarlyView.The mechanically interlocked Borromean rings are stabilized by π···π stacking interactions while the [2]catenane is stabilized by solvophobic effects. While the π···π interactions in the Borromean rings lead to severe luminescence quenching, the solvophobically assembled [2]catenane effectively circumvents these interactions, simultaneously restricting
Ye Lu +5 more
wiley +2 more sources
Topology‐Aware Machine Learning for High‐Throughput Screening of MOFs in C8 Aromatic Separation
Advanced Intelligent Discovery, EarlyView.We screened 15,335 Computation‐Ready, Experimental Metal–Organic Frameworks (CoRE‐MOFs) using a topology‐aware machine learning (ML) model that integrates structural, chemical, pore‐size, and topological descriptors. Top‐performing MOFs exhibit aromatic‐enriched cavities and open metal sites that enable π–π and C–H···π interactions, serving as ...
Yu Li, Honglin Li, Jialu Li, Wan‐Lu Li
wiley +1 more source
Angewandte Chemie, EarlyView.Targeted covalent inhibitors (TCI) containing cyclic imine warheads react with tyrosine and tryptophan residues via the Mannich reaction. These cyclic imine warheads show comparable reaction kinetics to cysteine‐reactive electrophiles commonly used in TCIs.
Sijie Wang +6 more
wiley +2 more sources
Advancements in Graphdiyne‐Based Multiscale Catalysts for Green Hydrogen Energy Conversion
Advanced Intelligent Discovery, EarlyView.This review systematically explores the fundamental characteristics of graphdiyne (GDY), cutting‐edge field of GDY‐based multiscale catalysts within sustainable energy conversion systems.Special emphasis is placed on the structure‒property relationships in different reactions.
Qian Xiao, Lu Qi, Siao Chen, Yurui Xue
wiley +1 more source
A Generalized Framework for Data‐Efficient and Extrapolative Materials Discovery for Gas Separation
Advanced Intelligent Discovery, EarlyView.This study introduces an iterative supervised machine learning framework for metal‐organic framework (MOF) discovery. The approach identifies over 97% of the best performing candidates while using less than 10% of available data. It generalizes across diverse MOF databases and gas separation scenarios.
Varad Daoo, Jayant K. Singh
wiley +1 more source
The Far Side of Carboranes: Anticancer Active Monocations and Ambiently Stable Dications
Angewandte Chemie, EarlyView.This work describes the synthesis of bench‐stable dicationic carboranes. Their enhanced electrophilicity is documented by opening the clusters with weak nucleophiles or dihydrogen. The surprising stability of positively charged carboranes in water enabled a study of their in vitro antiproliferative activity, which surpassed the effects of doxorubicin ...
Vlastimil Němec +10 more
wiley +2 more sources
Angewandte Chemie, EarlyView.We here developed a molecular tool for the optical control of UGGAA repeat RNA foci, a pathological hallmark of spinocerebellar ataxia type 31 (SCA31). The photoswitchable RNA‐binding ligand enabled reversible control of the RNA foci. UV irradiation induced the growth of the RNA foci, while subsequent visible light irradiation dissolved the structure ...
Yusuke Fujiwara +2 more
wiley +2 more sources
Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant [PDF]
, 2001 Anderson, RH +6 more
core +1 more source
Angewandte Chemie, EarlyView.Parallel mass spectrometry imaging acquires high mass resolution and tandem mass spectrometry images from 108 isolation windows in a single run. Spatial similarity networking clusters product ions by spatial distribution, enabling annotation of isomers and isobars as demonstrated for phospholipids and oxidized cholesterol in mouse and human brain ...
Varun V. Sharma +5 more
wiley +2 more sources