Results 181 to 190 of about 51,654 (310)

Force fluctuations regulation and the role of neurophysiological mechanisms throughout different isometric contraction intensities. [PDF]

Sci Rep
Oliveira JH, Gomes JS, Bauer P, Pezarat-Correia P, Vaz JR.   +4 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

British Journal of Pharmacology, EarlyView.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu, Zengbing Lu, Julia Yuen Hang Liu, Man Piu Ngan, Kai‐Hei Tse, John Anthony Rudd   +5 more
wiley   +1 more source

Gβγ subunit activation of KV7 and BKCa channels underlies calcitonin gene‐related peptide vasorelaxation in myogenic rat coronary resistance arteries

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose CGRP is a potent, clinically relevant coronary vasodilator known to play a role in cardioprotection. Here, we investigated the precise intracellular signalling pathways leading to vasodilation in small coronary arteries.
Lucy A. Donovan, JinHeng Lin, Milind Khashu, Christopher J. Garland, Kim A. Dora   +4 more
wiley   +1 more source

Effects of short- and long-term vibration therapy on maximum voluntary isometric contraction and muscle activity in quadriceps and antagonist muscles. [PDF]

J Phys Ther Sci
Miyara K, Yoshizato Y, Imai T, Nagamatsu T, Etoh S.   +4 more
europepmc   +1 more source

Fast Injective Mesh Parameterization via Beltrami Coefficient Prolongation

Computer Graphics Forum, EarlyView.
Abstract We present a highly efficient and robust method for free boundary injective parameterization of disk‐like triangle meshes with low isometric distortion. Harmonic function–based approaches, grounded in a strong mathematical framework, are widely employed.
G. Fargion, O. Weber
wiley   +1 more source

Acute effects of rapid versus sustained isometric contraction durations on countermovement jump performance in national level young male soccer players. [PDF]

Sci Rep
Grzyb W, Jarosz J.
europepmc   +1 more source

Non‐Rigid 3D Shape Correspondences: From Foundations to Open Challenges and Opportunities

Computer Graphics Forum, EarlyView.
Abstract Estimating correspondences between deformed shape instances is a long‐standing problem in computer graphics; numerous applications, from texture transfer to statistical modelling, rely on recovering an accurate correspondence map. Many methods have thus been proposed to tackle this challenging problem from varying perspectives, depending on ...
A. Zhuravlev, L. Bastian, D. Cao, N. El Amrani, P. Roetzer, V. Ehm, R. Marin, H. Nishizawa, S. Morishima, C. Theobalt, N. Navab, D. Cremers, F. Bernard, Z. Lähner, V. Golyanik   +14 more
wiley   +1 more source

Criterion Validity of the Isometric Contraction Test for Diagnosis of Axis I DC/TMD Considering Specific Muscles. [PDF]

J Oral Rehabil
Iglesias-Peón M, Mesa-Jiménez J, Fernández-de-Las-Peñas C, Peón CI, Iglesias NG, Villalba MB, Rodrigues-de-Souza DP, Alburquerque-Sendín F.   +7 more
europepmc   +1 more source

Handwriting speed in left‐handed children with right‐sided neonatal brachial plexus palsy

Developmental Medicine &Child Neurology, EarlyView.
This observational study investigated whether left‐handed children with right‐sided neonatal brachial plexus palsy (NBPP) exhibit reduced handwriting speed compared with typically developing left‐handed peers and explored determinants of any observed differences.
Rani De Pauw, Laura Tack, Anke Van Bladel, Ruth Van der Looven   +3 more
wiley   +1 more source