Results 201 to 210 of about 274,178 (292)

Passive thigh heating improves peak force production in younger adults and early isokinetic force production in younger and older adults

open access: yesExperimental Physiology, EarlyView.
Abstract Older adults often suffer from reduced physical capability relative to young adults, in part due to impaired muscle function. This study investigated the ergogenic effects of passive thigh heating on knee extensor torque production in healthy older versus younger adults.
Desmond Denny   +2 more
wiley   +1 more source

Lower limb blood flow responses during higher‐ and lower‐load bilateral leg press exercise

open access: yesExperimental Physiology, EarlyView.
Abstract The local blood flow response to resistance exercise (RE) is complicated by local muscular contractions and large swings in perfusion pressure. The magnitude of these responses might vary according to exercise intensity, number of sets and number of repetitions, and as a result, the local shear environment during RE remains uncharacterized. We
Eudoxia Zafiris   +3 more
wiley   +1 more source

Changes in motor unit conduction velocity after unilateral lower‐limb suspension and active recovery are correlated with muscle ion channel gene expression

open access: yesExperimental Physiology, EarlyView.
Abstract The effects of muscle disuse on the propagation of action potentials along motor unit (MU) muscle fibres, a key process for effective muscle activation and force generation, remain poorly understood. The aim of this study was to investigate changes in action potential propagation and to identify biological factors influencing these changes ...
Giacomo Valli   +12 more
wiley   +1 more source

Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats

open access: yesExperimental Physiology, EarlyView.
Abstract Serial sarcomere number (SSN) is reduced following immobilization of a muscle in a shortened position in male rodents thereby impairing muscle contractile function. However, in female rodents the effects of oestrogen on SSN and mechanical changes following immobilization and re‐ambulation are unknown.
Alexandra Q. Kirkup   +3 more
wiley   +1 more source

VEGF inhibitor‐induced vascular dysfunction involves redox‐sensitive PARP activation and SIRT1 disruption

open access: yesExperimental Physiology, EarlyView.
Abstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Karla B. Neves   +3 more
wiley   +1 more source

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

open access: yesExperimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin   +8 more
wiley   +1 more source

Small muscle mass aerobic exercise in health and disease: Unique insights into muscle vascular and metabolic control and performance

open access: yesExperimental Physiology, EarlyView.
Abstract Studies of small muscle mass exercise (SMME) have revealed that the peripheral O2 transport–utilization cascade is a dynamically regulated system in which perfusive and diffusive components can be selectively amplified, redistributed and mechanically limited depending on contraction pattern, recruitment strategy and intramuscular pressure ...
Shunsaku Koga   +4 more
wiley   +1 more source

Long‐term endurance running training and testosterone daily variation in ageing men; a comparative cross‐sectional study

open access: yesExperimental Physiology, EarlyView.
Abstract The aim of this study was to assess the relationship between long‐term endurance running training and daily variation in testosterone, which is known to diminish during ageing, in a comparative, cross‐sectional study. We recruited 45 male participants into four groups [young athletes (YA), young sedentary (YS), master athletes (MA) and elderly
Barbora Bartko   +7 more
wiley   +1 more source

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