Results 121 to 130 of about 56,118 (235)

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, Volume 3, Issue 1, Page 47-68, March 2026.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Rutin-Activated Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Attenuates Corneal and Heart Damage in Mice

Pharmaceuticals
Background: Corneal degeneration is a form of progressive cell death caused by multiple factors, such as diabetic retinopathy. It is the most well-known neural degenerative disease caused by macular degeneration in the aged and those with retinitis ...
Promise M. Emeka, Lorina I. Badger-Emeka, Krishnaraj Thirugnanasambantham, Abdulaziz S. Alatawi   +3 more
doaj   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, Volume 46, Issue 2, Page 445-474, March 2026.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

mTORC1 hyperactivation and resultant suppression of macroautophagy contribute to the induction of cardiomyocyte necroptosis by catecholamine surges

Physiological Reports
Previous studies revealed a controversial role of mechanistic target of rapamycin complex 1 (mTORC1) and mTORC1‐regulated macroautophagy in isoproterenol (ISO)‐induced cardiac injury.
Mingqi Cai, Penglong Wu, Wei Ni, Dong Huang, Xuejun Wang   +4 more
doaj   +1 more source

Temporal Characteristics and Management of Prolonged Sinus Pause Following Atrial Fibrillation Termination After Catheter Ablation—A Preliminary Study

Annals of Noninvasive Electrocardiology, Volume 31, Issue 2, March 2026.
Twelve of the 1330 patients who underwent AF catheter ablation showed PSP ≥ 3 s after AF termination post ablation. The temporal characteristics of PSP were described. Nine of the 12 patients had no need for permanent pacing. We concluded that a ‘watch‐and‐wait’ strategy could be adopted in these patients.
Yi Guo, Cheng Cai, Hongwu Chen, Kai Gu, Weizhu Ju, Gang Yang, Jiaojiao Shi, Zidun Wang, Hailei Liu, Xiaohong Jiang, Chang Cui, Mingfang Li, Minglong Chen   +12 more
wiley   +1 more source

Differential effects of isoproterenol on the activity of angiotensin-converting enzyme in the rat heart and aorta

Brazilian Journal of Medical and Biological Research, 1999
The excessive stimulation of beta-adrenergic receptors in the heart induces myocardial hypertrophy. There are several experimental data suggesting that this hypertrophy may also depend, at least partially, on the increase of local production of ...
Busatto V.C.W., Cunha V., Cicilini M.A., Mill J.G.   +3 more
doaj  

ISOPROTERENOL [PDF]

Anesthesiology, 1959
openaire   +1 more source

Coumarins and Their Derivatives in Animal Models of Asthma: A Systematic Review

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
Mast cells drive early allergic asthma by releasing histamine, interleukins and prostaglandins, causing airway hyperresponsiveness, mucus overproduction and inflammation. These events sustain symptoms and promote structural remodelling, contributing to the progression of the disease.
Iêda Maria dos Santos, João Lázaro de Oliveira Rocha, Edilson Beserra de Alencar Filho, Fabrício Souza Silva   +3 more
wiley   +1 more source

Bachmann's Bundle‐Related Atrial Tachycardias Following Catheter Ablation of Persistent Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, Volume 37, Issue 3, Page 561-571, March 2026.
ABSTRACT Background Atrial tachycardias (AT) after radiofrequency ablation (RFA) of atrial fibrillation (AF) may utilize Bachmann's bundle (BB). Due to their epicardial location, these ATs remain poorly understood. Objective To describe the electrophysiologic and anatomic basis of BB‐related ATs.
Nate Christian‐Miller, Mohammed Al‐Sadawi, Muazzum Shah, Kelly Arps, Amrish Deshmukh, Jackson J. Liang, Krit Jongnarangsin, Fred Morady, Hakan Oral, Aman Chugh, Michael Ghannam   +10 more
wiley   +1 more source

RBT‐1, a “preconditioning” agent, mitigates syndecan‐1 shedding in patients undergoing “on pump” cardiac surgery and following experimental AKI

Physiological Reports
During systemic stress, syndecan‐1 (SDC‐1) shedding into plasma results, implying endothelial damage. RBT‐1, a “preconditioning” agent, has been shown to mitigate postoperative complications following cardiac surgeries.
Ali C. M. Johnson, Richard A. Zager
doaj   +1 more source