Results 141 to 150 of about 93,473 (332)

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

mTORC1 hyperactivation and resultant suppression of macroautophagy contribute to the induction of cardiomyocyte necroptosis by catecholamine surges

Physiological Reports
Previous studies revealed a controversial role of mechanistic target of rapamycin complex 1 (mTORC1) and mTORC1‐regulated macroautophagy in isoproterenol (ISO)‐induced cardiac injury.
Mingqi Cai, Penglong Wu, Wei Ni, Dong Huang, Xuejun Wang   +4 more
doaj   +1 more source

A587 NALOXONE POTENTIATES INOTROPIC BUT NOT CHRONOTROPIC EFFECTS OF ISOPROTERENOL IN VITRO [PDF]

, 1990
R. B. Lechner
openalex   +1 more source

Type II Alveolar Epithelial Cells Promote Sepsis‐Induced Immunosuppression in Alveolar Macrophages via Exosomal lncRNA Rmrp Release

Advanced Science, Volume 13, Issue 1, 5 January 2026.
The S100A4/STAT3 axis promotes Rmrp transcription in AEC‐IIs and Rmrp expression in AEC‐II‐derived exosomes. Upon entry into AMs, Rmrp binds to and blocks the ubiquitination and degradation of ZFP36. Increased ZFP36 induced Pfkfb3 mRNA decay by binding to AREs in the 3′ UTR, curbing glycolysis and immune responses of AMs and aggravating SII and ...
Chengxi Liu, Weixia Xuan, Song Cao, Huayun Jia, Qian Wu, Xiaowu Tan, Qijie Wang, Xiaojun Li, Lisha Ding, Yaru Xiong, Meiyun Zhao, Longcheng Zheng, Yunzhu Xi, Jianhua Tan, Rong Li, Xulong Zhang, Wenjie Liu, Xu Wu   +17 more
wiley   +1 more source

Differential effects of isoproterenol on the activity of angiotensin-converting enzyme in the rat heart and aorta

Brazilian Journal of Medical and Biological Research, 1999
The excessive stimulation of beta-adrenergic receptors in the heart induces myocardial hypertrophy. There are several experimental data suggesting that this hypertrophy may also depend, at least partially, on the increase of local production of ...
Busatto V.C.W., Cunha V., Cicilini M.A., Mill J.G.   +3 more
doaj  

Time-dependent responses of rat troponin I and cardiac injury following isoproterenol administration [PDF]

Medicinski Glasnik, 2011
Aim To develop a rat model of myocardial infarction induced by isoproterenol (ISO). We investigated a type of histological myocardial changes and cardiac troponin I (TnI) kinetic. Methods The study has used adult, male, Wistar strain rats.
Sabaheta Hasić, Radivoj Jadrić, Emina Kiseljaković, Amina Valjevac, Zakira Mornjaković, Mira Winterhalter-Jadrić   +5 more
doaj  

Isoproterenol Increases BIS and Arousal during Catheter Ablation for Atrial Fibrillation [PDF]

, 2016
O’Neill DK, Anthony Aizer, Bloom Mj, Kline RP, Larry A. Chinitz, Patrick Linton, Thomas J. J. Blanck   +6 more
openalex   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun, Miriayi Alimujiang, Wenfei Li, Shuqin Chen, Yingying Su, Tingting Hu, Xuhong Lu, Yafen Ye, Ningning Bai, Fan Hu, Xiaoya Li, Rongrong Xu, Jun Xu, Jiarui Zhao, Yan Lu, Xiaojing Ma, Ying Yang   +16 more
wiley   +1 more source

Possible mechanism for changes in glycogen metabolism in unloaded soleus muscle [PDF]

Carbohydrate metabolism has been shown to be affected in a number of ways by different models of hypokinesia. In vivo glycogen levels in the soleus muscle are known to be increased by short-term denervation and harness suspension.
Henriksen, E. J., Tischler, M. E.
core   +1 more source

The role of CaMKII-dependent augmented INa,L in arrhythmias during acute β-adrenergic stimulation [PDF]

, 2018
The heart has evolved elaborate pathways for adapting function to acute stress stimuli [e.g. sympathetic stimulation of β-adrenergic receptors (β-ARs)].
Lane, Cemantha
core