Results 151 to 160 of about 93,473 (332)

Integrative Omics Defines Metabolic Biomarkers and Genetic Regulatory Mechanisms of Mortality Risk

Advanced Science, Volume 13, Issue 3, 14 January 2026.
Understanding mortality mechanisms remains a fundamental challenge. Through multi‐omics analysis of a three‐generation chicken model, are identified 45,585 mQTLs and establish a 16‐metabolite predictor of mortality. An inflammation‐growth trade‐off and evolutionarily conserved pathways involving butyrate–microbiota interactions and L‐cysteine's dual ...
Peihao Liu, Bingxing An, Jumei Zheng, Qiao Wang, Zhirui Yang, Zhengda Li, Dawei Liu, Fan Ying, Jie Wen, Lingzhao Fang, Guiping Zhao   +10 more
wiley   +1 more source

RBT‐1, a “preconditioning” agent, mitigates syndecan‐1 shedding in patients undergoing “on pump” cardiac surgery and following experimental AKI

Physiological Reports
During systemic stress, syndecan‐1 (SDC‐1) shedding into plasma results, implying endothelial damage. RBT‐1, a “preconditioning” agent, has been shown to mitigate postoperative complications following cardiac surgeries.
Ali C. M. Johnson, Richard A. Zager
doaj   +1 more source

Protective activities of silver nanoparticles containing Panax japonicus on apoptotic, inflammatory, and oxidative alterations in isoproterenol-induced cardiotoxicity [PDF]

Xu Xiao, Zhipeng Diao, Bo Zhao, Huajuan Xu, Shuying Yan, Huilin Chen   +5 more
openalex   +1 more source

Combining Adipose‐Derived Stromal Cell Spheroids and Melt Electrowritten Scaffolds for a 3D Adipose Model Mimicking Structure and Function of Fat Tissue

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
A 3D adipose tissue model is fabricated by combining melt electrowritten scaffolds with multicellular adipose‐derived stromal cell spheroids. The resulting constructs are characterized by a coherent, tissue‐like matrix. The lipid droplet size is tunable by oleic acid supplementation, reaching native‐like diameters.
Franziska Dusi, Tamara Weidemeier, Camilla Mussoni, Sabrina Stecher, Feven Berhanne, Philipp Stahlhut, Taufiq Ahmad, Jürgen Groll, Matthias Becker, Torsten Blunk, Petra Bauer‐Kreisel   +10 more
wiley   +1 more source

ISOPROTERENOL [PDF]

Anesthesiology, 1959
openaire   +1 more source

METTL1‐Mediated N7‐Methylguanosine tRNA Modification Alleviates Cardiac Ischemia/Reperfusion Injury by Modulating Mitochondrial Energy Metabolism

MedComm, Volume 7, Issue 1, January 2026.
During cardiac I/R injury, the level of METTL1 and tRNA m7G modification increases and then leads to CMs’ mitochondrial dysfunction and aggravated cardiac injury by modulating the transcription efficiency of ATPIF1. ABSTRACT Ischemic heart disease is one of the diseases with the highest morbidity and mortality in the world. The N7‐methylguanosine (m7G)
Yue Zhang, Mingyang Leng, Ruonan Wang, Xinyuan Tang, Zhenlu Cai, Liang Wang, Xiaoqi Shao, Hongtao Diao, Qinqiang Long, Xu Li, Yingzi Wu, Yuan Jiang, Haifeng Zhang, Haihai Liang, Jiao Guo   +14 more
wiley   +1 more source

Macrophage OTUD1‐CARD9 axis drives isoproterenol‐induced inflammatory heart remodelling

Clinical and Translational Medicine
Background Chronic inflammation contributes to the progression of isoproterenol (ISO)‐induced heart failure (HF). Caspase‐associated recruitment domain (CARD) families are crucial proteins for initiation of inflammation in innate immunity.
Jinfu Qian, Qinyan Wang, Jiachen Xu, Shiqi Liang, Qingsong Zheng, Xiaocheng Guo, Wu Luo, Weijian Huang, Xiaohong Long, Julian Min, Yi Wang, Gaojun Wu, Guang Liang   +12 more
doaj   +1 more source

Senescence-like Phenotype After Chronic Exposure to Isoproterenol in Primary Quiescent Immune Cells

Biomolecules
Chronic stress is associated with a higher risk for carcinogenesis as well as age-related diseases and immune dysfunction. There is evidence showing that psychological stress can contribute to premature immunosenescence.
Michael Laumann, Philipp Palombo, Judy Fieres, Mara Thomas, Gabriele Saretzki, Alexander Bürkle, Maria Moreno-Villanueva   +6 more
doaj   +1 more source

Isoproterenol-Induced Heart Failure Mouse Model Using Osmotic Pump Implantation.

Methods in molecular biology, 2018
S. Chang, Shuxun Ren, Christoph D. Rau, Jessica J Wang   +3 more
semanticscholar   +1 more source

Protective Effect of Squalene against Isoproterenol-Induced Myocardial Infarction in Rats

, 2005
K.H. Sabeena Farvin, R. Anandan, T.V. Sankar, Pullanniyil Gopalan Viswanathan Nair   +3 more
openalex   +2 more sources