Results 11 to 20 of about 91,861 (319)

Cardioprotective effects of compound ALM-802 on subendocardial ischemia models

Фармакокинетика и Фармакодинамика, 2021
The investigation purpose. N1-(2,3,4-trimethoxybenzyl)-N2-{2-[(2,3,4-trimethoxybenzyl)amino]ethyl}-1,2-ethanediamine (ALM-802 compounds) cardioprotective effect has been studied in rat models of subendocardial ischemia caused by isoproterenol and ...
I. B. Tsorin, V. V. Barchukov, M. B. Vititnova, A. M. Likhosherstov, G. V. Mokrov, S. A. Kryzhanovskii   +5 more
doaj   +1 more source

Type 2 MI induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart

Journal of Cellular and Molecular Medicine, 2020
Heart failure is the common final pathway of several cardiovascular conditions and a major cause of morbidity and mortality worldwide. Aberrant activation of the adaptive immune system in response to myocardial necrosis has recently been implicated in ...
E. Forte, M. Panahi, N. Baxan, F. Ng, J. Boyle, Jane A. Branca, Olivia Bedard, M. Hasham, Lindsay Benson, S. Harding, N. Rosenthal, S. Sattler   +11 more
semanticscholar   +1 more source

Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol. [PDF]

PLoS ONE, 2015
This study evaluated the chronotropic and inotropic responses to glucagon in spontaneously beating isolated right atria of rat heart. For comparison, we also investigated the effects resulting from stimulating β-adrenoceptors with isoproterenol in this ...
Beatriz Merino, Ivan Quesada, Jesús Hernández-Cascales   +2 more
doaj   +1 more source

Adrenergic Control of P2Y6 Receptor-Dependent Phagocytosis in Rodent and Human Microglia. [PDF]

Glia
Main Points Adrenergic signaling through ADRB2 modulates phagocytosis in microglia Crosstalk between ADRB2 and P2Y6 receptors conserved in rodent and human microglia ADRB2 activation inhibits both P2Y6 function and gene expression ABSTRACT Microglia, the resident immune cells of the central nervous system (CNS), are in constant survey of their ...
Deluc T, Ase A, Dorion MF, Maussion G, Tang Y, Lo RTM, Shlaifer I, Piscopo VE, Durcan TM, Stifani S, Séguéla P.   +10 more
europepmc   +2 more sources

Chemical chaperon 4-phenylbutric acid improves cardiac function following isoproterenol-induced myocardial infarction in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): 4-Phenyl butyric acid (4-PBA) is a chaperone-mediated autophagy (CMA) inducer, which eliminates unnecessary and damaged cellular components through lysosomal enzymes. It could reduce misfolded and unfolded proteins produced after myocardial
Fatemeh Vatankhah, Alireza Garjani, Haleh Vaez   +2 more
doaj   +1 more source

Cardioprotective Effect of Flibanserin against Isoproterenol-Induced Myocardial Infarction in Female Rats: Role of Cardiac 5-HT2A Receptor Gene/5-HT/Ca²⁺ Pathway

Pharmaceuticals, 2023
Myocardial infarction (MI) is a life-threatening ischemic disease and is one of the leading causes of morbidity and mortality worldwide. Serotonin (5-HT) release during myocardial ischemia plays an important role in the progression of myocardial cellular
Mohamed I. Ahmed, Heba M. A. Abdelrazek, Yasser M. Moustafa, Samar Z. Alshawwa, Maysa A. Mobasher, Basel A. Abdel-Wahab, Fathy Elsayed Abdelgawad, Dina M. Khodeer   +7 more
doaj   +1 more source

Effects of Isoproterenol and Melatonin Supplementation on In vitro Development of Parthenogenetic Activated Oocytes in Pig

Journal of Animal Reproduction and Biotechnology, 2016
In this study, to improve the in vitro development of various cells including cloned embryos, the effects that isoproterenol and melatonin have on in vitro development of porcine parthenogenetic oocytes were investigated.
Da-Un Jeong, Yun-Jin Yun, Hee-Sung Park
doaj   +1 more source

Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

BMC Cardiovascular Disorders, 2021
Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD.
Rachel T. Sullivan, Ngoc T. Lam, Margaret Haberman, Margaret J. Beatka, Muhammad Z. Afzal, Michael W. Lawlor, Jennifer L. Strande   +6 more
doaj   +1 more source

Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]

, 2018
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J., Patel, Jyoti Kandlikar, Patel, Parin J., Prystowsky, Eric N., Segar, Rachel   +4 more
core   +1 more source

Low-dose l-isoproterenol versus salbutamol in hospitalized pediatric patients with severe acute exacerbation of asthma: A double-blind, randomized controlled trial

Allergology International, 2019
Background: Although the guidelines in most countries do not recommend continuous inhalation of l-isoproterenol to treat pediatric patients with acute severe exacerbation of asthma, lower dose of l-isoproterenol has been widely used in Japan.
Toshio Katsunuma, Takao Fujisawa, Takanobu Maekawa, Kenichi Akashi, Yukihiro Ohya, Yuichi Adachi, Koji Hashimoto, Mihoko Mizuno, Takanori Imai, Mari S. Oba, Mayumi Sako, Yasuo Ohashi, Hidefumi Nakamura   +12 more
doaj   +1 more source