Results 11 to 20 of about 89,475 (303)

Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction.

open access: yesPLoS ONE, 2020
Sex-related differences in cardiovascular diseases are highly complex in humans and model-dependent in experimental laboratory animals. The objective of this work was to comprehensively investigate key sex differences in the response to acute and ...
Marianne K O Grant   +4 more
doaj   +2 more sources

Evaluation of Antioxidant and Immunity Activities of Quercetin in Isoproterenol-Treated Rats

open access: yesMolecules, 2012
The present study was designed to evaluate the effect of quercetin on myocardial oxidative stress and immunity function impairment induced by isoproterenol in rats.
Shaoping Lu, Lei Zhang, Hui Liu
doaj   +2 more sources

Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model. [PDF]

open access: yesPLoS Genetics, 2016
We aimed to understand the genetic control of cardiac remodeling using an isoproterenol-induced heart failure model in mice, which allowed control of confounding factors in an experimental setting.
Avetisyan, Rozeta   +8 more
core   +4 more sources

Isoproterenol and Pulmonary Circulation [PDF]

open access: bronzeCirculation, 1971
P N, Yu   +4 more
openaire   +4 more sources

Selective HDAC8 Inhibition Attenuates Isoproterenol-Induced Cardiac Hypertrophy and Fibrosis via p38 MAPK Pathway

open access: yesFrontiers in Pharmacology, 2021
Histone deacetylase (HDAC) expression and enzymatic activity are dysregulated in cardiovascular diseases. Among Class I HDACs, HDAC2 has been reported to play a key role in cardiac hypertrophy; however, the exact function of HDAC8 remains unknown.
Tingwei Zhao   +5 more
semanticscholar   +1 more source

Type 2 MI induced by a single high dose of isoproterenol in C57BL/6J mice triggers a persistent adaptive immune response against the heart

open access: yesJournal of Cellular and Molecular Medicine, 2020
Heart failure is the common final pathway of several cardiovascular conditions and a major cause of morbidity and mortality worldwide. Aberrant activation of the adaptive immune system in response to myocardial necrosis has recently been implicated in ...
E. Forte   +11 more
semanticscholar   +1 more source

Cardioprotective effect of Ginger in a rat model of myocardial damage and its possible intervention in PERK-ATF4-CHOP-PUMA apoptotic pathway [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
For today the exact mechanisms of myocardial infarction and ischemia/reperfusion injury are still not fully understood. ER stress and integrated stress response pathways are thought to play an essential role in myocardial damage. This includes activation
M. M. Mohammed   +3 more
doaj   +1 more source

Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]

open access: yes, 2018
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J.   +4 more
core   +1 more source

Effects of Isoproterenol and Melatonin Supplementation on In vitro Development of Parthenogenetic Activated Oocytes in Pig

open access: yesJournal of Animal Reproduction and Biotechnology, 2016
In this study, to improve the in vitro development of various cells including cloned embryos, the effects that isoproterenol and melatonin have on in vitro development of porcine parthenogenetic oocytes were investigated.
Da-Un Jeong, Yun-Jin Yun, Hee-Sung Park
doaj   +1 more source

The conventional isoproterenol-induced heart failure model does not consistently mimic the diaphragmatic dysfunction observed in patients.

open access: yesPLoS ONE, 2020
Heart failure (HF) impairs diaphragm function. Animal models realistically mimicking HF should feature both the cardiac alterations and the diaphragmatic dysfunction characterizing this disease.
Ignacio Cabrera-Aguilera   +8 more
doaj   +1 more source

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