Results 11 to 20 of about 93,473 (332)

Cardioprotective effects of compound ALM-802 on subendocardial ischemia models

Фармакокинетика и Фармакодинамика, 2021
The investigation purpose. N1-(2,3,4-trimethoxybenzyl)-N2-{2-[(2,3,4-trimethoxybenzyl)amino]ethyl}-1,2-ethanediamine (ALM-802 compounds) cardioprotective effect has been studied in rat models of subendocardial ischemia caused by isoproterenol and ...
I. B. Tsorin, V. V. Barchukov, M. B. Vititnova, A. M. Likhosherstov, G. V. Mokrov, S. A. Kryzhanovskii   +5 more
doaj   +1 more source

Glucagon Increases Beating Rate but Not Contractility in Rat Right Atrium. Comparison with Isoproterenol. [PDF]

PLoS ONE, 2015
This study evaluated the chronotropic and inotropic responses to glucagon in spontaneously beating isolated right atria of rat heart. For comparison, we also investigated the effects resulting from stimulating β-adrenoceptors with isoproterenol in this ...
Beatriz Merino, Ivan Quesada, Jesús Hernández-Cascales   +2 more
doaj   +1 more source

Effects of Isoproterenol and Melatonin Supplementation on In vitro Development of Parthenogenetic Activated Oocytes in Pig

Journal of Animal Reproduction and Biotechnology, 2016
In this study, to improve the in vitro development of various cells including cloned embryos, the effects that isoproterenol and melatonin have on in vitro development of porcine parthenogenetic oocytes were investigated.
Da-Un Jeong, Yun-Jin Yun, Hee-Sung Park
doaj   +1 more source

Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]

, 2018
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J., Patel, Jyoti Kandlikar, Patel, Parin J., Prystowsky, Eric N., Segar, Rachel   +4 more
core   +1 more source

The conventional isoproterenol-induced heart failure model does not consistently mimic the diaphragmatic dysfunction observed in patients.

PLoS ONE, 2020
Heart failure (HF) impairs diaphragm function. Animal models realistically mimicking HF should feature both the cardiac alterations and the diaphragmatic dysfunction characterizing this disease.
Ignacio Cabrera-Aguilera, Bryan Falcones, Alicia Calvo-Fernández, Begoña Benito, Esther Barreiro, Joaquim Gea, Ramon Farré, Isaac Almendros, Núria Farré   +8 more
doaj   +1 more source

Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

BMC Cardiovascular Disorders, 2021
Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD.
Rachel T. Sullivan, Ngoc T. Lam, Margaret Haberman, Margaret J. Beatka, Muhammad Z. Afzal, Michael W. Lawlor, Jennifer L. Strande   +6 more
doaj   +1 more source

Transcriptional changes during isoproterenol-induced cardiac fibrosis in mice

Frontiers in Molecular Biosciences, 2023
Introduction: β-adrenergic stimulation using β-agonists such as isoproterenol has been routinely used to induce cardiac fibrosis in experimental animal models.
Disha Nanda, Disha Nanda, Priyanka Pant, Priyanka Pant, Pratheusa Machha, Pratheusa Machha, Divya Tej Sowpati, Divya Tej Sowpati, Regalla Kumarswamy, Regalla Kumarswamy   +9 more
doaj   +1 more source

Successful Isoproterenol Treatment for Ventricular Fibrillation Storm in Early Repolarization Syndrome With SCN5A Mutation. [PDF]

Ann Noninvasive Electrocardiol
Suppression of VF storm in ERS with SCN5A mutation using isoproterenol. ABSTRACT A 58‐year‐old man experienced a ventricular fibrillation storm with prominent inferolateral J waves and was diagnosed with early repolarization syndrome. Initial coronary angiography showed no significant stenosis and the other evaluations for ventricular fibrillation were
Kim SS, Byoun JT, Joo D, Ko JS, Kim NH, Jeong HK.   +5 more
europepmc   +2 more sources

Effects of Curcumin Nanoparticles in Isoproterenol-Induced Myocardial Infarction

Oxidative Medicine and Cellular Longevity, 2019
Curcumin has anti-inflammatory, antioxidative, anticarcinogenic, and cardiovascular protective effects. Our study is aimed at evaluating the effects of pretreatment with curcumin nanoparticles (CCNP) compared to conventional curcumin (CC) on ...
Paul-Mihai Boarescu, I. Chirilă, A. Bulboacă, I. Bocșan, R. Pop, D. Gheban, S. Bolboacă   +6 more
semanticscholar   +1 more source

Sex‐specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles [PDF]

, 2018
Sex has a large influence on cardiac electrophysiological properties. Whether sex differences exist in apamin‐sensitive small conductance Ca2+‐activated K+ (SK) current (IKAS) remains unknown.
Chen, Mu, Chen, Peng-Sheng, Chen, Zhenhui, Everett, Thomas H., IV, Guo, Shuai, Lin, Shien-Fong, Rubart-von der Lohe, Michael, Wang, Zhuo, Weiss, James N., Xu, Dong-Zhu, Yin, Dechun   +10 more
core   +1 more source