Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model
Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD.
Rachel T. Sullivan +6 more
doaj +1 more source
Evaluation of Antioxidant and Immunity Activities of Quercetin in Isoproterenol-Treated Rats
The present study was designed to evaluate the effect of quercetin on myocardial oxidative stress and immunity function impairment induced by isoproterenol in rats.
Shaoping Lu, Lei Zhang, Hui Liu
doaj +1 more source
Sex‐specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles [PDF]
Sex has a large influence on cardiac electrophysiological properties. Whether sex differences exist in apamin‐sensitive small conductance Ca2+‐activated K+ (SK) current (IKAS) remains unknown.
Chen, Mu +10 more
core +1 more source
The cardioprotective effects of Trichopus zeylanicus leaves against isoproterenol-induced myocardial ischemia was studied. Wister strain rats were pretreated with T.
Sivanandham Velavan +2 more
doaj +2 more sources
Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure [PDF]
RATIONALE: In heart failure, myofilament proteins display abnormal phosphorylation, which contributes to contractile dysfunction. The mechanisms underlying the dysregulation of protein phosphorylation on myofilaments is not clear.
Barbagallo, Federica +15 more
core +1 more source
The beneficial effects of ivabradine against myocardial damage induced by isoproterenol in rats
We aimed to investigate the potential benefits of two doses of ivabradine (IVA)-an If sodium channel blocker against isoproterenol (ISO)-induced myocardial damage in rats.The rats were randomly divided into 4 groups: Control group (n=8); Saline was ...
Seyhan Polat +10 more
doaj +1 more source
Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells. [PDF]
The culture of human limbal epithelial stem/progenitor cells (LSCs) in the presence of animal components poses the risk of cross-species contamination in clinical applications.
Chen, Luxia +2 more
core +1 more source
Conjugated linoleic acid and betaine affect lipolysis in pig adipose tissue explants
Consumers’ demand of leaner meat products is a challenge. Although betaine and conjugated linoleic acid (CLA) have the potential to decrease porcine adipose tissue, their mode of action is poorly understood.
I. Fernández-Fígares +3 more
doaj +1 more source
Model of murine ventricular cardiac tissue for in vitro kinematic-dynamic studies of electromagnetic and beta2-adrenergic stimulation [PDF]
In a model of murine ventricular cardiac tissue in vitro, we have studied the inotropic effects of electromagnetic stimulation (frequency, 75 Hz), isoproterenol administration (10 μM), and their combination.
Cornacchione, Marisa +8 more
core +2 more sources
Isoproterenol is known to cause insulin resistance and is often used to treat bradyarrhythmias from atrioventricular block. We report a case of isoproterenol induced diabetic ketoacidosis in a 77-year-old female patient treated with isoproterenol for ...
Ryan Hoff, Chung-Kay Koh
doaj +1 more source

