Results 21 to 30 of about 89,475 (303)

Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

BMC Cardiovascular Disorders, 2021
Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD.
Rachel T. Sullivan, Ngoc T. Lam, Margaret Haberman, Margaret J. Beatka, Muhammad Z. Afzal, Michael W. Lawlor, Jennifer L. Strande   +6 more
doaj   +1 more source

Effects of Curcumin Nanoparticles in Isoproterenol-Induced Myocardial Infarction

Oxidative Medicine and Cellular Longevity, 2019
Curcumin has anti-inflammatory, antioxidative, anticarcinogenic, and cardiovascular protective effects. Our study is aimed at evaluating the effects of pretreatment with curcumin nanoparticles (CCNP) compared to conventional curcumin (CC) on ...
Paul-Mihai Boarescu, I. Chirilă, A. Bulboacă, I. Bocșan, R. Pop, D. Gheban, S. Bolboacă   +6 more
semanticscholar   +1 more source

Cardioprotective effect of Trichopus zeylanicus against myocardial ischemia induced by isoproterenol in rats

Bangladesh Journal of Pharmacology, 2009
The cardioprotective effects of Trichopus zeylanicus leaves against isoproterenol-induced myocardial ischemia was studied. Wister strain rats were pretreated with T.
Sivanandham Velavan, S. Selvarani, A. Adhithan   +2 more
doaj   +2 more sources

Sex‐specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles [PDF]

, 2018
Sex has a large influence on cardiac electrophysiological properties. Whether sex differences exist in apamin‐sensitive small conductance Ca2+‐activated K+ (SK) current (IKAS) remains unknown.
Chen, Mu, Chen, Peng-Sheng, Chen, Zhenhui, Everett, Thomas H., IV, Guo, Shuai, Lin, Shien-Fong, Rubart-von der Lohe, Michael, Wang, Zhuo, Weiss, James N., Xu, Dong-Zhu, Yin, Dechun   +10 more
core   +1 more source

Ginsenoside Re Improves Isoproterenol-Induced Myocardial Fibrosis and Heart Failure in Rats

Evidence-Based Complementary and Alternative Medicine, 2019
Objective. Panax ginseng is used widely for treatment of cardiovascular disorders in China. Ginsenoside Re is the main chemical component of P. ginseng.
Quanwei Wang, Xiaofeng Yu, Huali Xu, Xue-Zhong Zhao, D. Sui   +4 more
semanticscholar   +1 more source

Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation [PDF]

, 1986
This study was done to investigate aspects of control of extrarenal erythropoietin (Ep) production. To this end we studied the effects of three stimuli of renal Ep production in the adult, i.e.
Bauer, Christian, Jelkmann, W., Kurtz, Armin, Malmström, K., Pfuhl, A.   +4 more
core   +1 more source

In preeclampsia, maternal third trimester subcutaneous adipocyte lipolysis is more resistant to suppression by insulin than in healthy pregnancy [PDF]

, 2014
Obesity increases preeclampsia risk, and maternal dyslipidemia may result from exaggerated adipocyte lipolysis. We compared adipocyte function in preeclampsia with healthy pregnancy to establish whether there is increased lipolysis.
Forrest, Rachel., Freeman, Dilys J., Huda, Shahzya S., Jordan, Fiona, Paterson, Nicole, Sattar, Naveed   +5 more
core   +1 more source

Quercetin with lycopene modulates enzymic antioxidant genes pathway in isoproterenol cardiotoxicity in rats: Cardioprotection by quercetin & lycopene

Libyan Journal of Medicine, 2021
Quercetin (QN) is a naturally occurring phenolic compound found largely in vegetables and fruits. Lycopene (LY) is yet another natural phytocompound, found abundantly in red-colored fruits and vegetables.
LIJUAN Chen, XIAOLI Wu, WEIWEI Wang, XIA Wang, Jianhua Ma   +4 more
doaj   +1 more source

Isoproterenol-Dependent Activation of TRPM7 Protects Against Neurotoxin-Induced Loss of Neuroblastoma Cells

Frontiers in Physiology, 2020
Neuronal function and their survival depend on the activation of ion channels. Loss of ion channel function is known to induce neurodegenerative diseases such as Parkinson’s that exhibit loss of dopaminergic neurons; however, mechanisms that could limit ...
Yuyang Sun, Yuyang Sun, Amrita Kamat, Amrita Kamat, Brij B. Singh, Brij B. Singh   +5 more
doaj   +1 more source

Impairment of β-adrenergic regulation and exacerbation of pressure-induced heart failure in mice with mutations in phosphoregulatory sites in the cardiac CaV1.2 calcium channel

Frontiers in Physiology, 2023
The cardiac calcium channel CaV1.2 conducts L-type calcium currents that initiate excitation-contraction coupling and serves as a crucial mediator of β-adrenergic regulation of the heart.
Liam Hovey, Liam Hovey, Xiaoyun Guo, Yi Chen, Qinghang Liu, William A. Catterall   +5 more
doaj   +1 more source