Results 21 to 30 of about 56,897 (225)

Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

open access: yesBMC Cardiovascular Disorders, 2021
Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD.
Rachel T. Sullivan   +6 more
doaj   +1 more source

Evaluation of Antioxidant and Immunity Activities of Quercetin in Isoproterenol-Treated Rats

open access: yesMolecules, 2012
The present study was designed to evaluate the effect of quercetin on myocardial oxidative stress and immunity function impairment induced by isoproterenol in rats.
Shaoping Lu, Lei Zhang, Hui Liu
doaj   +1 more source

Cardioprotective Effect of Flibanserin against Isoproterenol-Induced Myocardial Infarction in Female Rats: Role of Cardiac 5-HT2A Receptor Gene/5-HT/Ca2+ Pathway

open access: yesPharmaceuticals, 2023
Myocardial infarction (MI) is a life-threatening ischemic disease and is one of the leading causes of morbidity and mortality worldwide. Serotonin (5-HT) release during myocardial ischemia plays an important role in the progression of myocardial cellular
Mohamed I. Ahmed   +7 more
doaj   +1 more source

Cardioprotective effect of Trichopus zeylanicus against myocardial ischemia induced by isoproterenol in rats

open access: yesBangladesh Journal of Pharmacology, 2009
The cardioprotective effects of Trichopus zeylanicus leaves against isoproterenol-induced myocardial ischemia was studied. Wister strain rats were pretreated with T.
Sivanandham Velavan   +2 more
doaj   +2 more sources

Conjugated linoleic acid and betaine affect lipolysis in pig adipose tissue explants

open access: yesAnimal, 2019
Consumers’ demand of leaner meat products is a challenge. Although betaine and conjugated linoleic acid (CLA) have the potential to decrease porcine adipose tissue, their mode of action is poorly understood.
I. Fernández-Fígares   +3 more
doaj   +1 more source

Peroxiredoxin 3 Inhibits Cardiac Fibrosis in Mice via NOX4-P38 Signalling [PDF]

open access: yesCell Journal, 2023
Objective: Peroxiredoxin-3 (Prx-3) is widely acknowledged as an antioxidant that protects against mitochondrialreactive oxygen species. Nonetheless, its role in cardiac fibrosis has not been elucidated. We aim to explore the roleand mechanism of Prx-3 in
Xiaoqi Xiong   +9 more
doaj   +1 more source

Isoproterenol Induced Insulin Resistance Leading to Diabetic Ketoacidosis in Type 1 Diabetes Mellitus

open access: yesCase Reports in Endocrinology, 2018
Isoproterenol is known to cause insulin resistance and is often used to treat bradyarrhythmias from atrioventricular block. We report a case of isoproterenol induced diabetic ketoacidosis in a 77-year-old female patient treated with isoproterenol for ...
Ryan Hoff, Chung-Kay Koh
doaj   +1 more source

Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction.

open access: yesPLoS ONE, 2020
Sex-related differences in cardiovascular diseases are highly complex in humans and model-dependent in experimental laboratory animals. The objective of this work was to comprehensively investigate key sex differences in the response to acute and ...
Marianne K O Grant   +4 more
doaj   +1 more source

Sulfur Dioxide Derivative Prevents the Prolongation of Action Potential During the Isoproterenol-Induced Hypertrophy of Rat Cardiomyocytes

open access: yesAnais da Academia Brasileira de Ciências, 2021
Exogenous SO2 is toxic especially to the pulmonary and cardiovascular system, similar to nitric-oxide, carbon-monoxide, and hydrogen-sulfide. Endogenous SO2 is produced in many cell types.
UĞUR DALAMAN   +4 more
doaj   +1 more source

Isoproterenol-Dependent Activation of TRPM7 Protects Against Neurotoxin-Induced Loss of Neuroblastoma Cells

open access: yesFrontiers in Physiology, 2020
Neuronal function and their survival depend on the activation of ion channels. Loss of ion channel function is known to induce neurodegenerative diseases such as Parkinson’s that exhibit loss of dopaminergic neurons; however, mechanisms that could limit ...
Yuyang Sun   +5 more
doaj   +1 more source

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