Results 11 to 20 of about 29,381 (199)

Cardioprotective effect of nicorandil on isoproterenol induced cardiomyopathy in the Mdx mouse model

open access: yesBMC Cardiovascular Disorders, 2021
Background Duchenne muscular dystrophy (DMD) associated cardiomyopathy is a major cause of morbidity and mortality. In an in vitro DMD cardiomyocyte model, nicorandil reversed stress-induced cell injury through multiple pathways implicated in DMD.
Rachel T. Sullivan   +6 more
doaj   +1 more source

Cardioprotective effect of Trichopus zeylanicus against myocardial ischemia induced by isoproterenol in rats

open access: yesBangladesh Journal of Pharmacology, 2009
The cardioprotective effects of Trichopus zeylanicus leaves against isoproterenol-induced myocardial ischemia was studied. Wister strain rats were pretreated with T.
Sivanandham Velavan   +2 more
doaj   +2 more sources

The beneficial effects of ivabradine against myocardial damage induced by isoproterenol in rats

open access: yesMedicine Science, 2023
We aimed to investigate the potential benefits of two doses of ivabradine (IVA)-an If sodium channel blocker against isoproterenol (ISO)-induced myocardial damage in rats.The rats were randomly divided into 4 groups: Control group (n=8); Saline was ...
Seyhan Polat   +10 more
doaj   +1 more source

Conjugated linoleic acid and betaine affect lipolysis in pig adipose tissue explants

open access: yesAnimal, 2019
Consumers’ demand of leaner meat products is a challenge. Although betaine and conjugated linoleic acid (CLA) have the potential to decrease porcine adipose tissue, their mode of action is poorly understood.
I. Fernández-Fígares   +3 more
doaj   +1 more source

Cardioprotective effect of Ginger in a rat model of myocardial damage and its possible intervention in PERK-ATF4-CHOP-PUMA apoptotic pathway [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2023
For today the exact mechanisms of myocardial infarction and ischemia/reperfusion injury are still not fully understood. ER stress and integrated stress response pathways are thought to play an essential role in myocardial damage. This includes activation
M. M. Mohammed   +3 more
doaj   +1 more source

Isoproterenol Induced Insulin Resistance Leading to Diabetic Ketoacidosis in Type 1 Diabetes Mellitus

open access: yesCase Reports in Endocrinology, 2018
Isoproterenol is known to cause insulin resistance and is often used to treat bradyarrhythmias from atrioventricular block. We report a case of isoproterenol induced diabetic ketoacidosis in a 77-year-old female patient treated with isoproterenol for ...
Ryan Hoff, Chung-Kay Koh
doaj   +1 more source

Isoproterenol-Dependent Activation of TRPM7 Protects Against Neurotoxin-Induced Loss of Neuroblastoma Cells

open access: yesFrontiers in Physiology, 2020
Neuronal function and their survival depend on the activation of ion channels. Loss of ion channel function is known to induce neurodegenerative diseases such as Parkinson’s that exhibit loss of dopaminergic neurons; however, mechanisms that could limit ...
Yuyang Sun   +5 more
doaj   +1 more source

Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction.

open access: yesPLoS ONE, 2020
Sex-related differences in cardiovascular diseases are highly complex in humans and model-dependent in experimental laboratory animals. The objective of this work was to comprehensively investigate key sex differences in the response to acute and ...
Marianne K O Grant   +4 more
doaj   +1 more source

Protective Effects of L-2-Oxothiazolidine-4-Carboxylate during Isoproterenol-Induced Myocardial Infarction in Rats: In Vivo Study

open access: yesLife, 2022
This study aimed to evaluate the cardioprotective effects of L-2-oxothiazolidine-4-carboxylate (OTC) against isoproterenol (ISO)-induced acute myocardial infarction (MI) in rats.
Marija Angelovski   +6 more
doaj   +1 more source

Assessment of evaluated pulmonary vascular resistance by isoproterenol infusion in patients with atrial septal defects

open access: yesJournal of Medicine in Scientific Research, 2018
Aim and Background Congenital heart diseases constitute a major category of disorders associated with pulmonary hypertension in atrial septal defect there is tendency to repair essentially all large defect except some of those with severe obstructive ...
Amir S Michael
doaj   +1 more source

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