Results 51 to 60 of about 648 (166)

Discovering the effects of octylisothiazolinone: analysis of physiological changes in the Mediterranean mussel (Mytilus galloprovincialis)

Ecotoxicology and Environmental Safety
Isothiazolinones represent a class of biocidal agents employed in industrial and medical formulations. Among this class, the 2-n-octyl-4-isothiazolin-3-one (OIT) is increasingly recognized as an emerging contaminant in aquatic systems.
Cristiana Roberta Multisanti, Federica Impellitteri, Giorgia Cannatà, Annalisa Cotugno, Monia Perugini, Giuseppe Piccione, Caterina Faggio, Maria Giovanna Rizzo   +7 more
doaj   +1 more source

Iso‐ and Benzisothiazolinone Inhibitors of Monoacylglycerol Lipase: Exploring On‐Target Activity Through Scaffold Decoration and In Situ Warhead Generation

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
We explore covalent allosteric targeting of MGL regulatory cysteines using iso‐ and benzisothiazolinone scaffolds. Combining mechanism‐based warhead release with structure‐guided scaffold decoration to improve molecular recognition, this study probes strategies to achieve selective on‐target engagement beyond the catalytic site. Monoacylglycerol lipase
Edoardo Rocca, Annalida Bedini, Laura Scalvini, Francesca Galvani, Riccardo Castelli, Lorenzo Sarcone, Adriano Recchia, Fabiola Fanini, Adren Tran, Silvia Rivara, Gilberto Spadoni, Daniele Piomelli, Marco Mor   +12 more
wiley   +1 more source

Impact of isothiazolinone biocides on gonadal steroid production: Focus on 3β-hydroxysteroid dehydrogenase inhibition

Ecotoxicology and Environmental Safety
Isothiazolinone biocides have been widely used as disinfectants during the COVID-19 pandemic. However, their effects on gonadal steroidogenesis remain unclear.
Ke Zheng, Shufang Qi, Fangzheng Shan, Rong Cui, Shaowei Wang, Wanyu Li, Jin Yang, Ren-shan Ge, Yiyan Wang   +8 more
doaj   +1 more source

Methylisothiazolinone and Methylchloroisothiazolinone New Insights [PDF]

European Medical Journal Dermatology, 2013
Methylisothiazolinone (MI), along with Kathon™ CG (methylchloroisothiazolinone/MI), are widely used preservatives to prevent bacterial overgrowth in aqueous solutions of various types of cosmetic, household, and industrial products. Because of its high
Ana Rita Rodrigues-Barata, Luis Conde-Salazar   +1 more
doaj  

Evaluation of physiological changes in Mytilus galloprovincialis exposed to an isothiazolinone-based compound: A multi-marker approach

Ecotoxicology and Environmental Safety
The present study aims to assess, through a multi-marker analysis, the changes in physiological parameters in the Mediterranean mussel, Mytilus galloprovincialis, due to exposure to methylchloroisothiazolinone (CMIT). The CMIT is an isothiazolinone-based
Cristiana Roberta Multisanti, Maria Giovanna Rizzo, Federica Impellitteri, Kateryna Yunko, Lesya Gnatyshyna, Monia Perugini, Oksana Stoliar, Caterina Faggio   +7 more
doaj   +1 more source

Microbial Community Analyses of the Deteriorated Storeroom Objects in the Tianjin Museum Using Culture-Independent and Culture-Dependent Approaches

Frontiers in Microbiology, 2018
In the storeroom C7 of the Tianjin Museum, one wooden desk and two leather luggages dated back to Qing dynasty (1644-1912 AD) presented viable microbial contamination.
Zijun Liu, Yanhong Zhang, Fengyu Zhang, Cuiting Hu, Genliang Liu, Jiao Pan   +5 more
doaj   +1 more source

Microbial community analysis and biodeterioration of waterlogged archaeological wood from the Nanhai No. 1 shipwreck during storage

Scientific Reports, 2018
Wooden shipwrecks are a significant part of the underwater cultural heritage. In 2007, the Nanhai No. 1 shipwreck was salvaged from the seabed and moved into the Marine Silk Road Museum, where it is still stored in a water tank. We analysed the microbial
Zijun Liu, Tongtong Fu, Cuiting Hu, Dawa Shen, Nicola Macchioni, Lorena Sozzi, Yue Chen, Jie Liu, Xingling Tian, Qinya Ge, Zhengteng Feng, Huiru Liu, Zhiguo Zhang, Jiao Pan   +13 more
doaj   +1 more source

Preservatives as important etiologic factors of allergic contact dermatitis

Medycyna Pracy, 2015
Background: Preservatives present in cosmetics and other industrial products can cause allergic contact dermatitis. The aim of the study was to assess the frequency of allergy to selected preservatives in consecutive patients examined due to contact ...
Beata Kręcisz, Dorota Chomiczewska-Skóra, Marta Kieć-Świerczyńska   +2 more
doaj   +1 more source

Occupations at risk of developing contact allergy to isothiazolinones in Danish contact dermatitis patients:results from a Danish multicentre study (2009-2012)

, 2014
BACKGROUND: In recent years, the prevalence of contact allergy to isothiazolinones has reached epidemic levels. Few studies have presented data on occupations at risk of developing contact allergy to isothiazolinones.OBJECTIVES: To present demographics ...
Schwensen, Jakob F, Jakob F. Schwensen, Menné, Torkil, Mette Sommerlund, Andersen, Klaus Ejner; id_orcid, Klaus E. Andersen, Sommerlund, Mette, Jeanne D. Johansen, Schwensen, Jakob Ferløv, Andersen, Klaus E, Torkil Menné, Johansen, Jeanne D   +11 more
core   +1 more source

Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products

Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman, Mathieu Frenette, Sylvain Canesi   +2 more
wiley   +1 more source