Procoagulant Effects of Isothiazolinone Biocides, Benzisothiazolinone and Octylisothiazolinone in Platelets [PDF]
ToxicsIsothiazolinones are commonly used biocides that are extensively used in industrial areas and household products. The extensive usage of isothiazolinones raises concerns regarding their adverse human health effects.
Ju Hee Choi, Keunyoung Kim
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Trans- and Multigenerational Effects of Isothiazolinone Biocide CMIT/MIT on Genotoxicity and Epigenotoxicity in Daphnia magna [PDF]
Toxics, 2023 The mixture of 5-chloro-2-methylisothiazol-3(2H)-one and 2-methylisothiazol-3(2H)-one, CMIT/MIT, is an isothiazolinone biocide that is consistently detected in aquatic environments because of its broad-spectrum usage in industrial fields.
Jiwan Kim, Jinhee Choi
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Disposition of Aerosols of Isothiazolinone-Biocides: BIT, MIT and OIT [PDF]
Toxics, 2022 Biocides are widely used in everyday life, and accordingly, human exposure to them is inevitable. Especially, the inhalational exposure of humans to biocides and resultant respiratory toxicity are gaining public interest due to the recent catastrophe ...
Seungmi Lee +5 more
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Pharmacological targeting of the NLRP3 LRR domain with isothiazolinones overcomes CRID3-resistant inflammation [PDF]
EMBO Molecular MedicineThe NLRP3 inflammasome is a key driver in inflammatory, infectious, metabolic, and neurodegenerative diseases. Although the NLRP3 inhibitor CRID3 (also known as MCC950) exhibits potent activity, it cannot inhibit several hyperactive NLRP3 mutations ...
Hawon Woo +14 more
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Isothiazolinone dysregulates the pattern of miRNA secretion: Endocrine implications for neurogenesis
Environment International, 2023 Isothiazolinones are extensively used as preservatives and disinfectants in personal care products and household items. The unintended exposure of humans and animals to isothiazolinones has led to increasing concerns about their health hazards.
Paul K S Lam +2 more
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Analysis of Microbial Communities and Microbial Preservation of the Qilin Screen Wall and Text Brick Wall in the Jinshanling Great Wall [PDF]
MicroorganismsThe Jinshanling Great Wall is an important part of the Ming Great Wall, the most important material cultural heritage of China, and is currently facing a significant threat of microbial degradation due to the widespread biological weathering of open-air ...
Zhiqian Guan +6 more
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Ecotoxicology and Environmental SafetyIsothiazolinone disinfectants constitute a class of broad-spectrum antimicrobial agents due to the pandemic of COVID-19. The aim of this study was to assess the impacts of six distinct isothiazolinone disinfectants on the activity of 17β-hydroxysteroid ...
Ren-Shan Ge, Yunbing Tang, Xiaoheng Li
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Analysis and prevention of microbial degradation of shadow puppetry artifacts preserved in the National Shadow Puppetry Museum in Chengdu [PDF]
Frontiers in MicrobiologyShadow puppetry, an integral and crucial component of China’s intangible cultural heritage, currently faces the significant threat of microbial degradation. This is primarily due to the organic materials used in its artifacts.
Yu Wang +9 more
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Ecotoxicology and Environmental SafetyIsothiazolinone biocides have been widely used as disinfectants during the COVID-19 pandemic. However, their effects on gonadal steroidogenesis remain unclear.
Ren-Shan Ge, Rong Cui
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Marine antifouling biocide 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one disrupts sediment microbiome structure and function: insights from absolute quantification and enzyme activity dynamics [PDF]
Applied and Environmental MicrobiologyThe organic booster biocide DCOIT (4,5-dichloro-2-n-octyl-4-isothiazolin-3-one) is widely used in marine antifouling systems, yet its ecological impacts on sediment microbiomes remain poorly understood.
Jiaxin Zhang +6 more
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