Isothiazolinones in Disposable Rubber Gloves-Results of Chemical Analysis. [PDF]
Contact DermatitisChemical analysis revealed benzisothiazolinone (BIT) in 30/54 disposable rubber gloves (27 nitrile rubber gloves, 2 neoprene rubber gloves and 1 natural rubber glove) in concentrations of 0.3–73.7 ppm. Methylisothiazolinone (MI) was found in six nitrile rubber gloves in small concentrations.
Suuronen K +3 more
europepmc +3 more sources
Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles [PDF]
Molecules, 2020 The importance of isothiazole and of compounds containing the isothiazole nucleus has been growing over the last few years. Isothiazolinones are used in cosmetic and as chemical additives for occupational and industrial usage due to their bacteriostatic ...
Vânia Silva +5 more
doaj +2 more sources
Skin sensitization risk assessment: A comparative evaluation of 3 isothiazolinone biocides
, 1999 Many of the chemicals in common use possess, to some degree, a capacity to cause skin sensitization. Consequently, it is important to conduct a thorough and accurate risk assessment when it can be anticipated that such chemicals are likely to come into ...
Wahlberg, Jan E. +4 more
core +11 more sources
High VoltageThe authors explore the limitations of silicone rubber (SR) in tropical environments due to its lack of antimicrobial activity. The use of a 2‐methylisothiazol‐3(2H)‐one compound with 5‐chloro‐2‐methylisothiazol‐3(2H)‐one is proposed as an efficient and ...
Shifang Yang +4 more
doaj +2 more sources
Development of a Generic Analysis Method for Isothiazolinones in Consumer Products Prompted by Increased Sensitisation to Benzisothiazolinone. [PDF]
Contact DermatitisAn analysis method using simple instrumentation was developed to investigate isothiazolinones in cosmetic and household products in patch test investigations. Analysis showed that concentrations of benzisothiazolinone can be several orders of magnitude higher than those of chloromethylisothiazolinone/methylisothiazolinone in products to which skin ...
Farbrot A +8 more
europepmc +2 more sources
Ecotoxicology and Environmental SafetyThe present study aims to assess, through a multi-marker analysis, the changes in physiological parameters in the Mediterranean mussel, Mytilus galloprovincialis, due to exposure to methylchloroisothiazolinone (CMIT). The CMIT is an isothiazolinone-based
Cristiana Roberta Multisanti +7 more
doaj +2 more sources
An Unexpected Culprit: Allergic Contact Dermatitis Caused by Benzyl Alcohol in Moist Toilet Paper. [PDF]
Contact DermatitisContact Dermatitis, Volume 95, Issue 1, Page 113-115, July 2026.
Rozas LM +3 more
europepmc +2 more sources
Iso- and Benzisothiazolinone Inhibitors of Monoacylglycerol Lipase: Exploring On-Target Activity Through Scaffold Decoration and In Situ Warhead Generation. [PDF]
ChemMedChemWe explore covalent allosteric targeting of MGL regulatory cysteines using iso‐ and benzisothiazolinone scaffolds. Combining mechanism‐based warhead release with structure‐guided scaffold decoration to improve molecular recognition, this study probes strategies to achieve selective on‐target engagement beyond the catalytic site. Monoacylglycerol lipase
Rocca E +12 more
europepmc +2 more sources
Study on Quantitative Structure - Activity Relationship of Substituted - 2 - Phenylisothiazolinones Compounds [PDF]
Cailiao Baohu, 2022 Quantitative structure - activity relationship studies the relationship between molecular structure and antibacterial activity, which can provide a theoretical basis for predicting the molecular structure of new compounds, synthesizing and designing new ...
YANG Xing, YAN Ying, ZHOU Hao, WU Laiming, CAI Lankun
doaj +1 more source
Isothiazolinones as Novel Candidate Insecticides for the Control of Hemipteran Insects
Antibiotics, 2021 Hemipteran insects, such as whiteflies, aphids and planthoppers, resemble one of the most important pest groups threating food security. While many insecticides have been used to control these pests, many issues such as insecticide resistance have been ...
Wenze He +3 more
doaj +1 more source